Inbunden, Tyska, 2022
2 017 kr
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Frank Petersen – författare
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10 produkter
10 produkter
- Inbunden, Tyska, 2024
314 kr
Skickas inom 10-15 vardagar
Das Sachbuch bietet einen fesselnden Einblick in die Geschichte und die medizinische Bedeutung des gefürchteten Mutterkorns. Dabei wird der Bogen von frühen medizinischen Schriften Mesopotamiens, Griechenlands und Chinas bis zu den industriellen und akademischen Laboren der pharmazeutischen Forschung des 20. Jahrhunderts gespannt.Über 1000 Jahre hinweg lösten die hochaktiven Inhaltsstoffe des pflanzenpathogenen Pilzes entsetzliche Massenvergiftungen in Europa aus. Das Buch beleuchtet, wie sich zur ausschließlichen Versorgung der an Ergotismus leidenden Menschen der Antoniterorden formierte und wie Ärzte die Zusammenhänge zwischen dem Mutterkornpilz und der Vergiftung über roggenbasierte Nahrungsmittel aufklärten.Besonders faszinierend ist die Darstellung, wie es der pharmazeutischen Naturstoffforschung gelang, aus den isolierten Wirkstoffen des Mutterkorns schließlich Medikamente zu entwickeln, die für die Modernisierung der Medizin essenziell wurden. Dieser Teil der Geschichte zeigt, wie aus der Dunkelheit des Mittelalters heraus bedeutende Fortschritte für die menschliche Gesundheit erzielt wurden.Ein weiterer Höhepunkt des Buches ist die Erörterung, wie aus diesen Arbeiten das LSD hervorging, das für die Aufklärung der chemischen Grundlagen der Psyche und den Beginn der Psychopharmakologie so bedeutsam wurde.Für alle, die sich für Medizingeschichte, Pharmakologie und die Chemie der Psyche interessieren, ist dieses Buch ein absolutes Muss.Zudem bietet das Buch einen Einblick in die kulturellen, historischen und medizinischen Aspekte rund um das Mutterkorn und regt zum Nachdenken über die Bedeutung und die potenziellen Anwendungen des Mutterkorns in der modernen Medizin an. 367 kr
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Das Sachbuch bietet einen fesselnden Einblick in die Geschichte und die medizinische Bedeutung des gefürchteten Mutterkorns. Dabei wird der Bogen von frühen medizinischen Schriften Mesopotamiens, Griechenlands und Chinas bis zu den industriellen und akademischen Laboren der pharmazeutischen Forschung des 20. Jahrhunderts gespannt.
Über 1000 Jahre hinweg lösten die hochaktiven Inhaltsstoffe des pflanzenpathogenen Pilzes entsetzliche Massenvergiftungen in Europa aus. Das Buch beleuchtet, wie sich zur ausschließlichen Versorgung der an Ergotismus leidenden Menschen der Antoniterorden formierte und wie Ärzte die Zusammenhänge zwischen dem Mutterkornpilz und der Vergiftung über roggenbasierte Nahrungsmittel aufklärten.
Besonders faszinierend ist die Darstellung, wie es der pharmazeutischen Naturstoffforschung gelang, aus den isolierten Wirkstoffen des Mutterkorns schließlich Medikamente zu entwickeln, die für die Modernisierung der Medizin essenziell wurden. Dieser Teil der Geschichte zeigt, wie aus der Dunkelheit des Mittelalters heraus bedeutende Fortschritte für die menschliche Gesundheit erzielt wurden.
Ein weiterer Höhepunkt des Buches ist die Erörterung, wie aus diesen Arbeiten das LSD hervorging, das für die Aufklärung der chemischen Grundlagen der Psyche und den Beginn der Psychopharmakologie so bedeutsam wurde.
Für alle, die sich für Medizingeschichte, Pharmakologie und die Chemie der Psyche interessieren, ist dieses Buch ein absolutes Muss.
Zudem bietet das Buch einen Einblick in die kulturellen, historischen und medizinischen Aspekte rund um das Mutterkorn und regt zum Nachdenken über die Bedeutung und die potenziellen Anwendungen des Mutterkorns in der modernen Medizin an.
- E-bokEngelska, 2025
718 kr
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There are countless reports on microorganisms and their special abilities. The saga of the ergot fungus is perhaps the most unusual of them all. The unique history of this plant pathogenic microbe, which began with its infection of grasses, is told through a broad storyline that stretches from the early medical writings of Mesopotamia, Greece, and China, to the industrial and academic laboratories of pharmaceutical research in the 21st century....
Among cultivated grasses, the ergot fungus mainly infests rye. Its overwintering structure, the black-purple ergot kernel, grows out of the ears of the grain. The highly active substances it contains caused mass poisonings in Europe over a period of 1,000 years, in the course of which the victims suffered from terrible symptoms of illness. Only in the 17th century, doctors recognized ergot as the corpus delicti for the regularly recurring waves of mass poisoning. The development of drugs from pure ergot compounds is one of the fascinating contributions of pharmaceutical natural product and medicinal chemistry and was of great importance for the modernization of medicine. A straight line can be drawn from this research to the synthesis of LSD, whose accidentally observed psychotropic effect revealed the chemical basis of the psyche. In combination with other centrally active substances, the LSD studies opened the therapeutic research field of psychopharmacology.
The ergot fungus stands for legendary advances in pharmaceutical science and human therapy. At the same time, the people who investigated this unique microorganism scientifically, for a wide variety of reasons, became part of its cultural history. Throughout the centuries, they have kept the wheels turning - an innovative power which is still effective today.
- Häftad, Engelska, 2026
509 kr
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There are countless reports on microorganisms and their special abilities. The saga of the ergot fungus is perhaps the most unusual of them all. The unique history of this plant pathogenic microbe, which began with its infection of grasses, is told through a broad storyline that stretches from the early medical writings of Mesopotamia, Greece, and China, to the industrial and academic laboratories of pharmaceutical research in the 21st century....Among cultivated grasses, the ergot fungus mainly infests rye. Its overwintering structure, the black-purple ergot kernel, grows out of the ears of the grain. The highly active substances it contains caused mass poisonings in Europe over a period of 1,000 years, in the course of which the victims suffered from terrible symptoms of illness. Only in the 17th century, doctors recognized ergot as the corpus delicti for the regularly recurring waves of mass poisoning. The development of drugs from pure ergot compounds is one of the fascinating contributions of pharmaceutical natural product and medicinal chemistry and was of great importance for the modernization of medicine. A straight line can be drawn from this research to the synthesis of LSD, whose accidentally observed psychotropic effect revealed the chemical basis of the psyche. In combination with other centrally active substances, the LSD studies opened the therapeutic research field of psychopharmacology.The ergot fungus stands for legendary advances in pharmaceutical science and human therapy. At the same time, the people who investigated this unique microorganism scientifically, for a wide variety of reasons, became part of its cultural history. Throughout the centuries, they have kept the wheels turning - an innovative power which is still effective today. - Inbunden, Engelska, 2025
509 kr
Skickas inom 10-15 vardagar
There are countless reports on microorganisms and their special abilities. The saga of the ergot fungus is perhaps the most unusual of them all. The unique history of this plant pathogenic microbe, which began with its infection of grasses, is told through a broad storyline that stretches from the early medical writings of Mesopotamia, Greece, and China, to the industrial and academic laboratories of pharmaceutical research in the 21st century....Among cultivated grasses, the ergot fungus mainly infests rye. Its overwintering structure, the black-purple ergot kernel, grows out of the ears of the grain. The highly active substances it contains caused mass poisonings in Europe over a period of 1,000 years, in the course of which the victims suffered from terrible symptoms of illness. Only in the 17th century, doctors recognized ergot as the corpus delicti for the regularly recurring waves of mass poisoning. The development of drugs from pure ergot compounds is one of the fascinating contributions of pharmaceutical natural product and medicinal chemistry and was of great importance for the modernization of medicine. A straight line can be drawn from this research to the synthesis of LSD, whose accidentally observed psychotropic effect revealed the chemical basis of the psyche. In combination with other centrally active substances, the LSD studies opened the therapeutic research field of psychopharmacology.The ergot fungus stands for legendary advances in pharmaceutical science and human therapy. At the same time, the people who investigated this unique microorganism scientifically, for a wide variety of reasons, became part of its cultural history. Throughout the centuries, they have kept the wheels turning - an innovative power which is still effective today. - Del 65 - Progress in Drug Research
Natural Compounds as Drugs, Volume I
Inbunden, Engelska, 20071 698 kr
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The use of herbal medicines, their preparation and application in human therapy, was described for the first time in history by the Sumerians approximately 5000 years ago. Even earlier in India and China, a highly sophisticated medical system with plant-based therapies had been dev- oped. Along with the rise of the later empires, this knowledge was further expanded and institutionalized, while moving westwards to Egypt, Greece, and to the Arabic world, having a considerable influence on human th- apy – until today. Not all of these traditional medicines, although partially in medical practice still today, can be considered as efficacious or useful according to Western therapeutic standards, often due to the fact that the tra- tional disease categories cannot be easily translated into the “language” of Western medicine. The identification of active principles from plant preparations often failed, as the biological activity could not be enriched. However, there are numerous examples like morphine, quinine, salicylic acid, rivastigmine, digitalis glycosides, reserpine, or artemisinine, where the correlation between plant extract and the modern medicine, based on a single entity drug, was successfully established. All of these natural pr- ucts originated from traditional medical practice and opened the door to today’s medical indication areas, fundamentally enriching our knowledge of the pathophysiology and underlying biochemistry of diseases. - E-bokPDF, Engelska, 2007
2 127 kr
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The use of herbal medicines, their preparation and application in human therapy, was described for the first time in history by the Sumerians approximately 5000 years ago. Even earlier in India and China, a highly sophisticated medical system with plant-based therapies had been dev- oped. Along with the rise of the later empires, this knowledge was further expanded and institutionalized, while moving westwards to Egypt, Greece, and to the Arabic world, having a considerable influence on human th- apy – until today. Not all of these traditional medicines, although partially in medical practice still today, can be considered as efficacious or useful according to Western therapeutic standards, often due to the fact that the tra- tional disease categories cannot be easily translated into the “language” of Western medicine. The identification of active principles from plant preparations often failed, as the biological activity could not be enriched. However, there are numerous examples like morphine, quinine, salicylic acid, rivastigmine, digitalis glycosides, reserpine, or artemisinine, where the correlation between plant extract and the modern medicine, based on a single entity drug, was successfully established. All of these natural pr- ucts originated from traditional medical practice and opened the door to today’s medical indication areas, fundamentally enriching our knowledge of the pathophysiology and underlying biochemistry of diseases. - Del 66 - Progress in Drug Research
Natural Compounds as Drugs, Volume II
Inbunden, Engelska, 20081 698 kr
Skickas inom 10-15 vardagar
The use of substances derived from plants, fungi, bacteria and marine organisms has a long tradition in medicine. Together with their derivatives, and synthetic compounds deduced from natural product precursors, they represent a major part of today's pharmaceutical market. In molecular biological research, natural products also play an important role as tool compounds in pathway screening and validation of target identification concepts. They provide innovative opportunities in drug discovery, leading to a detailed understanding of biological pathways and revealing the functions of involved enzymes or receptors.This book highlights the biodiversity-driven approaches which are now of eminent importance in natural products research. It addresses the question why natural products display such a complex chemical information, what makes them often unique and what their characteristics are. Practical questions such as supply of natural substances and production optimization strategies are also covered. - E-bokPDF, Engelska, 2008
2 127 kr
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The use of substances derived from plants, fungi, bacteria and marine organisms has a long tradition in medicine. Together with their derivatives, and synthetic compounds deduced from natural product precursors, they represent a major part of today''s pharmaceutical market.
In molecular biological research, natural products also play an important role as tool compounds in pathway screening and validation of target identification concepts. They provide innovative opportunities in drug discovery, leading to a detailed understanding of biological pathways and revealing the functions of involved enzymes or receptors.
This book highlights the biodiversity-driven approaches which are now of eminent importance in natural products research. It addresses the question why natural products display such a complex chemical information, what makes them often unique and what their characteristics are. Practical questions such as supply of natural substances and production optimization strategies are also covered.
