Frank W Putnam – författare

The Plasma Proteins: Structure, Function, and Genetic Control, Second Edition, Volume I is a systematic account of the structure, function, and genetic control of plasma proteins. Clinical relevance is introduced in terms of principles, with emphasis on human proteins. Animal proteins are also used as examples in some cases.Comprised of nine chapters, this volume begins with a historical background on plasma proteins, along with their nomenclature, characterization, and genetic markers. The primary structure and three-dimensional conformation of plasma proteins are also considered. The discussion then turns to the chemical, physical, and biological properties of various plasma proteins such as serum albumin, lipoproteins, and immunoglobulins. Subsequent chapters deal with protease inhibitors in plasma; purification, physical properties, chemical composition, and molecular structure of transferrin; biosynthesis and metabolism of serum lipoproteins; and physical, chemical, and functional properties of the proteins of the complement system. The final chapter is devoted to ?2-microglobulin, with particular reference to its purification and physical properties; chemical composition and structure; physiological function, biosynthesis, and catabolism; and presence and function in cell membranes.This monograph will be of interest to molecular biologists and biochemists.

Geared to the needs of mental health practitioners unfamiliar with dissociative disorders, this volume presents a comprehensive and integrated approach to diagnosis and treatment. Each step--from first interview to final post-integrative treatment--is systematically reviewed, with detailed instructions on specific diagnostic and therapeutic techniques and examples of their clinical applications. Concise yet thorough, the volume offers expert advice on such topics as how to foster a strong therapeutic alliance, how to manage crises, and what basic errors to avoid.

Old Before Their Time is the deeply personal story of a 35-year scientific investigation of the effects of childhood sexual abuse on child development and adult outcomes. The startling conclusion is that early childhood trauma accelerates biological aging of the body and the mind.The reader will gain a comprehensive perspective on the many ways in which maltreatment embeds itself in a child’s mind, body, and behavior and is expressed across generations. It concludes that the prevention of child maltreatment is the single most powerful target for the prevention of mental illness, and for reducing premature death from common illnesses.One in five women and one in eight men report a history of child sexual abuse. As adults, victims often have questions about how it has affected them. Old Before Their Time provides answers as well as recommendations to improve child protection and treatment services which impact millions of children and families every year. Written for a general science reader, this engaging book is well-referenced for professionals who work with children or adults with histories of child maltreatment.

Old Before Their Time is the deeply personal story of a 35-year scientific investigation of the effects of childhood sexual abuse on child development and adult outcomes. The startling conclusion is that early childhood trauma accelerates biological aging of the body and the mind.The reader will gain a comprehensive perspective on the many ways in which maltreatment embeds itself in a child’s mind, body, and behavior and is expressed across generations. It concludes that the prevention of child maltreatment is the single most powerful target for the prevention of mental illness, and for reducing premature death from common illnesses.One in five women and one in eight men report a history of child sexual abuse. As adults, victims often have questions about how it has affected them. Old Before Their Time provides answers as well as recommendations to improve child protection and treatment services which impact millions of children and families every year. Written for a general science reader, this engaging book is well-referenced for professionals who work with children or adults with histories of child maltreatment.

Old Before Their Time is the deeply personal story of a 35-year scientific investigation of the effects of childhood sexual abuse on child development and adult outcomes. The startling conclusion is that early childhood trauma accelerates biological aging of the body and the mind.The reader will gain a comprehensive perspective on the many ways in which maltreatment embeds itself in a child's mind, body, and behavior and is expressed across generations. It concludes that the prevention of child maltreatment is the single most powerful target for the prevention of mental illness, and for reducing premature death from common illnesses.One in five women and one in eight men report a history of child sexual abuse. As adults, victims often have questions about how it has affected them. Old Before Their Time provides answers as well as recommendations to improve child protection and treatment services which impact millions of children and families every year. Written for a general science reader, this engaging book is well-referenced for professionals who work with children or adults with histories of child maltreatment.

Old Before Their Time is the deeply personal story of a 35-year scientific investigation of the effects of childhood sexual abuse on child development and adult outcomes. The startling conclusion is that early childhood trauma accelerates biological aging of the body and the mind.The reader will gain a comprehensive perspective on the many ways in which maltreatment embeds itself in a child's mind, body, and behavior and is expressed across generations. It concludes that the prevention of child maltreatment is the single most powerful target for the prevention of mental illness, and for reducing premature death from common illnesses.One in five women and one in eight men report a history of child sexual abuse. As adults, victims often have questions about how it has affected them. Old Before Their Time provides answers as well as recommendations to improve child protection and treatment services which impact millions of children and families every year. Written for a general science reader, this engaging book is well-referenced for professionals who work with children or adults with histories of child maltreatment.

The Plasma Proteins: Structure, Function, and Genetic Control, Second Edition, Volume II describes the plasma proteins in a systematic and integrated way, with emphasis on structure, function, and genetic control. The text presents the perspectives and a global look at plasma proteins; well-characterized major proteins; and integrated systems of plasma proteins. The emphasis of the studies is mainly on human proteins. Clinical relevance is introduced in terms of principles rather than detail. Biochemists, molecular biologists, physiologists, and laboratory researchers in the field of medicine will find the book useful.

The Plasma Proteins, Volume I: Isolation, Characterization, and Function focuses on the reactions, properties, characteristics, and transformations of plasma proteins. The selection first offers information on the fractionation and isolation of purified components by precipitation methods and electrophoretic and ultracentrifugal analysis of normal human serum. Discussions focus on correlation of electrophoretic and ultracentrifugal results, electrophoretic analytical methodology and results, parameters influencing protein solubility, and techniques for the separation of proteins by precipitation methods. The text then ponders on the chromatography of plasma proteins and chemical composition and molecular parameters of purified plasma proteins. The manuscript elaborates on plasma albumin and macroglobulins and high molecular weight antibodies. Topics include immunological properties, physical and chemical properties of normal and pathological macroglobulins, purity, homogeneity, and variability, denaturation behavior, and sulfhydryl groups, mercaptalbumin, and the mercury dimer. The book then examines glycoproteins and metal-binding plasma proteins and cation transport. The selection is a highly recommended reference for biochemists and clinicians interested in plasma proteins.

Presenting a comprehensive developmental approach, this book examines the origins and course of normal and pathological dissociation in children and adolescents. The volume illustrates the critical connection between pathological dissociation and trauma, and provides a clear synthesis of what is known about the psychobiology of dissociative disorders and the effects of pathological dissociation on cognition, memory, and behavior. Amply illustrated with clinical vignettes, the book describes an array of diagnostic and treatment techniques and includes reproducible copies of validated dissociation scales for all age groups.