G. Dallenbach-Hellweg – författare

Die Ovarialtumoren gehoren heute mit zu den haufigsten Tumoren des weiblichen Genitale. Ihre morphologische Differentialdiagnostik und die sich darauf aufbauende gezielte Therapie ist aufgrund der Vielfalt dieser Tumoren ungleich viel komplizierter als in anderen Organen. Dement- sprechend liegt der Schwerpunkt dieses Buches auf dem Gebiet der Histo- pathologie. Spezialkenntnisse insbesondere tiber die selteneren Formen der Ovarialtumoren hangen von groBen Fallzahlen abo Hier ist der inter- nationale Erfahrungsaustausch von vorrangiger Bedeutung. Die derzeit weltweit anerkannte histogenetische Klassifikation der WHO erfahrt an- hand der Erfahrungen an drei deutschen Frauenkliniken kleine Erganzun- gen und Variationen. Einige Lander, Z. B. Israel verfUgen tiber groBe epi- demiologische Untersuchungen, deren Ergebnisse korrelierend aufgenom- men sind. Zur klinischen Diagnostik wurden in den letzten lahren mo- dernste Untersuchungsmt;thoden neu eingefUhrt; ihre Anwendung setzt jedoch individuell anzupassende kritische Indikationsstellungen voraus.AbschlieBend werden die sich sehr differenziert auf der histologischen Diagnostik aufbauenden modernen Moglichkeiten einer gezielten Thera- pie der Ovarialtumoren ausfUhrlich diskutiert. Hier steht die Chemothera- pie im Vordergrund. 1m Hinblick auf die Frage einer Hormonbehandlung kommt neuerdings auch dem Rezeptornachweis im Tumorgewebe Bedeu- tung zu. Diese Zusammenstellung spricht somit gleichermaBen Pathologen, Onkologen und Gynakologen an und will versuchen, gegenseitige Infor- mationslticken der Fachexperten auf dem Gesamtgebiet der Problematik der Ovarialtumoren in zumutbarer Klirze zu schlieJ3en. Daher nehmen ge- rade die selteneren und bisher weniger bekannten Tumoren in Bild und Text einen verhaltnismaBig breiten Raum ein auf Kosten der hinlanglich bekannten haufigeren Formen, bei denen Spezia1fragen der Differenti- diagnostik aufgrund neuester Erkenntnisse im Vordergrund stehen.

Few subjects in gynecology, let alone in medicine in general, have provoked such inter­ est or study as cervical cancer. Although the wealth of monographs and books publish­ ed on the subject would seem to obviate the need for more, the great advances made in the medical sciences and in gynecological experience and techniques in recent years call for, if not require, a new book on cervical cancer to bring together the latest ideas and trends in its methods of study, diagnosis, and treatment. Although precancerous lesions have become more common, the number of women developing invasive cervical carcinomas has not increased, owing in part to programs of patient education, in part to screening examinations sponsored by the government. The gynecologist is now able to detect with well-tried and proved techniques precan­ cerous states of the cervix, and to treat these effectively before they become invasive cancer. Accordingly, recent interests in cervical cancer have shifted from the classic descrip­ tion of invasive carcinoma to newer studies of cause, diagnosis, therapy, and terminol­ ogy of its precursors. As the reader will learn, epidemiological studies as guides for the future account for, and justifiably so, an important part of this book. New knowledge about changes in the morphology of cervical carcinoma confirms its dependency on hormonal stimulation. Furthermore, modem experiences serve to explain which therapy is best. Overlapping of concepts and opinions between some chapters could not be avoided.

Few subjects in gynecology, let alone in medicine in general, have provoked such inter­ est or study as cervical cancer. Although the wealth of monographs and books publish­ ed on the subject would seem to obviate the need for more, the great advances made in the medical sciences and in gynecological experience and techniques in recent years call for, if not require, a new book on cervical cancer to bring together the latest ideas and trends in its methods of study, diagnosis, and treatment. Although precancerous lesions have become more common, the number of women developing invasive cervical carcinomas has not increased, owing in part to programs of patient education, in part to screening examinations sponsored by the government. The gynecologist is now able to detect with well-tried and proved techniques precan­ cerous states of the cervix, and to treat these effectively before they become invasive cancer. Accordingly, recent interests in cervical cancer have shifted from the classic descrip­ tion of invasive carcinoma to newer studies of cause, diagnosis, therapy, and terminol­ ogy of its precursors. As the reader will learn, epidemiological studies as guides for the future account for, and justifiably so, an important part of this book. New knowledge about changes in the morphology of cervical carcinoma confirms its dependency on hormonal stimulation. Furthermore, modem experiences serve to explain which therapy is best. Overlapping of concepts and opinions between some chapters could not be avoided.

The great advances in knowledge of endometrial physiology and pathology made since the first edition of this monograph have compelled me to revise it. Although I have maintained the general plan in this second edition, many sections, especially those dealing with endometrial tumors and with endometrial changes caused by hormonal treatment, contraceptive agents and devices have been in large part rewritten. The sections on procedures for obtaining endometrial tissue, on functional disturbances and spontaneous abortion have been changed or expanded to incorporate new facts from recent discoveries that now appear to be significant. Only time, however, will prove their true value. All chapters have been scrutinized to insure they comprise only precise and up-to-date information. To complement the revisions and to replace previous illustrations 36 new photographs have been added. In accordance with all these improvements, the bibliography has been amended, with pertinent new references included and those deemed obsolete omitted. The author acknowledges with gratitude the help from thoughtful correspon­ dents who have suggested valuable changes or brought to her attention omissions or errors that inadvertently appeared in the first edition. Every effort has been made to rectify such mistakes. Again, the Springer Verlag has earned my hearty thanks for their patience and proficiency in preparing this new edition. MannheimjHeidelberg, March 1975 GISELA DALLENBACH-HELLWEG Foreword to the German Edition During life form changes. From the form seen we can often interpret function.