Advances in the Biosciences 1: Schering Symposium on Endocrinology, Berlin, May 26 to 27, 1967 is a collection of papers presented at the Schering Symposium on Endocrinology held in Berlin, Germany, on May 26-27, 1967.Contributors explore a wide range of topics relating to endocrinology, including the radioimmunoassay of gonadotropins; steroid transformations in human and rat testes; hormonal control of sexual behavior in adult rats; and regulation of synthesis and release of anterior pituitary hormones both in vitro and in vivo.This book is comprised of 25 chapters and begins by analyzing a hormone, prepared from liquor folliculi and whole ovaries, that causes typical estrus in spayed rats, followed by a discussion on the preparation of a crystalline ovarian hormone from the urine of pregnant women. Subsequent chapters focus on hypothalamic control and pathways of release of neurohypophysial hormones; effect of amino acids and proteins on insulin secretion in human subjects; hormonal regulation of sexual behavior in adult rats; and some aspects of steroid transformations in the testes of human subjects and of rats with experimental cryptorchidism or feminization. Results of ultrastructural and subcellular studies of storage and release of neurohypophysial hormones are also presented.This monograph will be a useful resource for endocrinologists.

Advances in the Biosciences 13: Hormones and Embryonic Development investigates various aspects of hormones and embryonic development, including their physiological and pharmacological effects. More specifically, this volume considers which maternal hormones are essential for normal mammalian embryonic development, as well as the time course of the occurrence of endocrine systems during mammalian fetal development. In addition, it examines the role of maternal or fetal hormones in the induction and differentiation processes during embryonic or fetal development.Comprised of 13 chapters, this book begins with an analysis of the metabolic effects of insulin and glucagon in fetal and newborn rats, as well as their physiologic significance during the perinatal period in rat and other species. The next chapter deals with sexual differentiation in the rat fetus; how hormones regulate sexual development and disrupt sexual differentiation; the role of progesterone and estrone in pregnant rats fed a protein-free diet; and effects of brain implants of testosterone propionate in newborn hamsters on sexual differentiation. The link between diethylstilbestrol ingestion during pregnancy and development of clear-cell adenocarcinoma in the vagina and cervix of the female offspring is also examined.This monograph will be of interest to biologists, bioscientists, physiologists, and pharmacologists.

Advances in the Biosciences 1: Schering Symposium on Endocrinology, Berlin, May 26 to 27, 1967 is a collection of papers presented at the Schering Symposium on Endocrinology held in Berlin, Germany, on May 26-27, 1967.Contributors explore a wide range of topics relating to endocrinology, including the radioimmunoassay of gonadotropins; steroid transformations in human and rat testes; hormonal control of sexual behavior in adult rats; and regulation of synthesis and release of anterior pituitary hormones both in vitro and in vivo.This book is comprised of 25 chapters and begins by analyzing a hormone, prepared from liquor folliculi and whole ovaries, that causes typical estrus in spayed rats, followed by a discussion on the preparation of a crystalline ovarian hormone from the urine of pregnant women. Subsequent chapters focus on hypothalamic control and pathways of release of neurohypophysial hormones; effect of amino acids and proteins on insulin secretion in human subjects; hormonal regulation of sexual behavior in adult rats; and some aspects of steroid transformations in the testes of human subjects and of rats with experimental cryptorchidism or feminization. Results of ultrastructural and subcellular studies of storage and release of neurohypophysial hormones are also presented.This monograph will be a useful resource for endocrinologists.

Advances in the Biosciences 13: Hormones and Embryonic Development investigates various aspects of hormones and embryonic development, including their physiological and pharmacological effects. More specifically, this volume considers which maternal hormones are essential for normal mammalian embryonic development, as well as the time course of the occurrence of endocrine systems during mammalian fetal development. In addition, it examines the role of maternal or fetal hormones in the induction and differentiation processes during embryonic or fetal development.Comprised of 13 chapters, this book begins with an analysis of the metabolic effects of insulin and glucagon in fetal and newborn rats, as well as their physiologic significance during the perinatal period in rat and other species. The next chapter deals with sexual differentiation in the rat fetus; how hormones regulate sexual development and disrupt sexual differentiation; the role of progesterone and estrone in pregnant rats fed a protein-free diet; and effects of brain implants of testosterone propionate in newborn hamsters on sexual differentiation. The link between diethylstilbestrol ingestion during pregnancy and development of clear-cell adenocarcinoma in the vagina and cervix of the female offspring is also examined.This monograph will be of interest to biologists, bioscientists, physiologists, and pharmacologists.