Gary W. Caldwell – författare

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9 produkter

Cytochrome P450
In Vitro Methods and Protocols
Av Zhengyin Yan, Gary W. Caldwell
Inbunden, 2021
1889 kr
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This collection explores detailed experimental protocols necessary for setting up a variety of in vitro cytochrome P450 (CYP) assays that are vital in selecting drug candidates in a drug discovery pipeline. Major factors affecting drug metabolism include CYP expression levels, kinetic parameters …
Cytochrome P450
In Vitro Methods and Protocols
Av Gary W. Caldwell, Zhengyin Yan
E-bok, 2021
1838 kr
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This collection explores detailed experimental protocols necessary for setting up a variety of in vitro cytochrome P450 (CYP) assays that are vital in selecting drug candidates in a drug discovery pipeline. Major factors affecting drug metabolism include CYP expression levels, kinetic parameters …
Cytochrome P450
In Vitro Methods and Protocols
Av Zhengyin Yan, Gary W. Caldwell
Häftad, 2022
1336 kr
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This collection explores detailed experimental protocols necessary for setting up a variety of in vitro cytochrome P450 (CYP) assays that are vital in selecting drug candidates in a drug discovery pipeline. Major factors affecting drug metabolism include CYP expression levels, kinetic parameters …
Optimization in Drug Discovery
In Vitro Methods
Av Gary W. Caldwell, Zhengyin Yan
Häftad, 2016
1557 kr
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Thoroughly revised and updated, Optimization in Drug Discovery: In Vitro Methods, Second Edition presents a wide spectrum of in vitro assays including formulation, plasma binding, absorption and permeability, cytochrome P450 (CYP) and UDP-glucuronosyltransferases (UGT) metabolism, CYP inhibition …
Optimization in Drug Discovery
Av Zhengyin Yan, Gary W. Caldwell
Inbunden, 2004
1668 kr
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Recent analyses of drug attrition rates reveal that a significant number of drug candidates fail in the later stage of clinical development owing to absorption, distribution, metabolism, elimination (ADME), and toxicity issues. Lead optimization in drug discovery, a process attempting to uncover …
Optimization in Drug Discovery
Av Gary W. Caldwell, Zhengyin Yan
E-bok, 2008
2174 kr
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Recent analyses of drug attrition rates reveal that a significant number of drug candidates fail in the later stage of clinical development owing to absorption, distribution, metabolism, elimination (ADME), and toxicity issues. Lead optimization in drug discovery, a process attempting to uncover …
Optimization in Drug Discovery
Av Zhengyin Yan, Gary W. Caldwell
Häftad, 2010
1668 kr
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Recent analyses of drug attrition rates reveal that a significant number of drug candidates fail in the later stage of clinical development owing to absorption, distribution, metabolism, elimination (ADME), and toxicity issues. Lead optimization in drug discovery, a process attempting to uncover …
Optimization in Drug Discovery
In Vitro Methods
Av Gary W. Caldwell, Zhengyin Yan
Inbunden, 2013
2221 kr
Lägg i varukorg
Thoroughly revised and updated, Optimization in Drug Discovery: In Vitro Methods, Second Edition presents a wide spectrum of in vitro assays including formulation, plasma binding, absorption and permeability, cytochrome P450 (CYP) and UDP-glucuronosyltransferases (UGT) metabolism, CYP inhibition …
Optimization in Drug Discovery
In Vitro Methods
Av Zhengyin Yan, Gary W. Caldwell
E-bok, 2013
2020 kr
Lägg i varukorg
Thoroughly revised and updated, Optimization in Drug Discovery: In Vitro Methods, Second Edition presents a wide spectrum of in vitro assays including formulation, plasma binding, absorption and permeability, cytochrome P450 (CYP) and UDP-glucuronosyltransferases (UGT) metabolism, CYP inhibition …