Geoffrey H. Bourne – författare

Hearts and Heart-Like Organs, Volume 2: Physiology provides anatomical and physiological perspectives of the heart from invertebrates to humans. This book deals with the physiology of the heart, its evolution, and the effects of hormones, stress, exercise, hypoxia, bed rest, and the control of the coronary system. Organized into 11 chapters, this volume begins with an overview of the effects of hormones on the heart and the diversity of types of humoral agents that influence cardiac function. This text then examines the precursors in prostaglandin biosynthesis. Other chapters consider the synthesis of thyroid hormone that occurs within the follicles of the thyroid gland and proceeds through a series of steps. This book discusses as well the concepts of cardiac function, including the neural control of the heart and biochemical mechanisms of adrenergic and cholinergic regulation of myocardial contractility. The final chapter deals with the various factors of coronary resistance. This book is a valuable resource for cardiologists and physiologists.

Nonhuman Primates and Medical Research focuses on the contributions of nonhuman primates to biomedical research. The selection first elaborates on monkeys and yellow fever, cell cultures, and tuberculosis and bacterial infection. Discussions focus on bacterial diseases, tuberculosis, radiobiology, antibody formation and pharmacologic studies, cell-culture media and methods, the rhesus monkey and early history of yellow fever research, and monkeys and yellow fever in the future. The text then elaborates on virus research, models for investigation in parasitology, and primates as organ donors in transplantation studies in man. The manuscript examines the importance of monkeys for the study of malignant tumors in man; use of primates in cardiovascular research; and humanlike diseases in anthropoid apes. Topics include etiology of humanlike disease in anthropoid apes, atherosclerosis, historical aspects of primate research, selection of a suitable primate, and preeclampsia. The text also ponders on primate studies and human evolution and mental retardation. The selection is a valuable reference for researchers interested in the contributions of nonhuman primates to biomedical research.

The Biochemistry and Physiology of Bone focuses on the advancements of techniques, methodologies, and approaches involved in bone studies, including general anatomy, tissues, collagen fibers, and calcification. The selection first offers information on the general anatomy and histology of bone and bone as a mechanical engineering problem. Topics include strength of healing fractures, nervous influences on bone, growth of the skull, bone strength, primary constituents of bony tissue, and types and organization of bony tissue. The text then elaborates on the ground substance of connective tissue and cartilage, organic matrix of bone, and collagen fibers of connective tissue. The publication takes a look at the ultrastructure and distribution of mineral salts in bone tissue, osteoblast, and osteoclast. Discussions focus on microscopical appearances, integration of morphological and histochemical studies, cytochemistry, distribution of inorganic salts in bone tissue, relation of collagen to its environment, and structure of collagen fibers. The publication also examines pathological calcification, effects of radiation on bone, parathyroid glands and bone, and anterior pituitary regulation of skeletal development. The selection is a dependable source of data for researchers interested in the biochemistry and physiology of bone.

The Structure and Function of Muscle, Second Edition, Volume I, Structure Part 1 deals primarily with structure, considering muscles from the macroscopic, embryonic, histological, and molecular points of view. This book discusses the anatomy of muscles and their relation to movement and posture; how muscles are used in the body; development of striated muscle; and histochemistry of developing skeletal and cardiac muscle. The postembryonic growth and differentiation of striated muscle; skeletal muscle in culture; and molecular basis of contraction in cross-striated muscles are also elaborated. This volume likewise covers the obliquely striated muscle and crustacean and arthropod muscle. This publication is beneficial to biologists and medical students interested in the various aspects and structure of the muscles.

Medical and Biological Problems of Space Flight covers the proceedings of the conference held in Nassau, the Bahamas. The book focuses on the biological and medical problems of space flight, as well as advanced manned space systems, cardiovascular adaptability, weightlessness, and remote visual monitoring. The selection first offers information on the development of manned space vehicles and advanced manned space systems, including manned satellite and space stations, safety considerations, and man-machine aspects. The book also takes a look at Marsflight II space cabin simulator and device for simulating weightlessness. Discussions focus on the psychological aspects of real and simulated weightlessness; physiological effects of real and simulated weightlessness; and critique of simulation excellence. The publication examines maintenance of cardiovascular adaptability during prolonged weightlessness and the physical, biological, and medical aspects of weightlessness. The text then ponders on remote visual monitoring during extended space missions and cosmic ray shower production in manned space vehicles. Topics include electron-proton showers and limitations imposed by communications on transmission of pictorial information from a space vehicle. The selection is a valuable reference for readers interested in the medical and biological problems of space flight.

Division of Labor in Cells, Second Edition focuses on cytological techniques used in studies related to the complexities of cell structure and function. The publication first elaborates on the structure of cell membrane and cytoplasm, including the endoplasmic reticulum, nature of microsomes, differential centrifugation, and permeability of cell membranes. The book then takes a look at the mitochondria and Golgi apparatus. Topics include metabolic substances found in the mitochondria, plant cells, protein and fat metabolism, lysosomes, metabolism of carbohydrates, plastids and chloroplasts, and chemical nature of the mitochondria. The manuscript elaborates on gland cells, muscle fibers, and nerve fibers and the nucleus and nucleic acids. Discussions focus on the striated muscle fiber, nucleocytoplasmic relationships, nucleic acids of the nucleus, DNA, RNA, and genes, chromosomes, and spindle fibers. The publication is a vital reference for researchers interested in cell structure and function.

paper he discussed the results whim had been obtained from his studies of the adrenal gland. The results he obtained are probably best told in his own words:-"To see whether the adrenal cortex contains any such reducing agent the gland was cut with a knife into halves-which were immersed in a 0. 4% AgN0 solution. In a few minutes the cortical part 3 was seen to darken through the deposition of reduced metallic silver. In a quarter of an hour the cut surface of the cortex turned completely black while the medulla remained largely uncoloured. The black colouration ends towards the medulla with a sharp margin, which corresponds to the anatomical margin between the medulla and cortex. Like the medulla, other organs, such as brain, liver and muscle remain practically uncoloured. " When the gland was immersed in a mixture of potassium iodate and acetic acid-a reagent for adrenalin, the medulla became violet in colour and the cortex remained colourless. SZENT-GYORGYI therefore came to the conclusion that:-"The adrenal cortex therefore, contains some specific highly reducing agent which can be no arte fact, since its action is produced in the almost fresh material." Methyl alcohol extracts of the cortex reduced neutral silver nitrate almost instantaneously and when the portions of the interrenal glands of Elasmobranm fishes were treated with silver nitrate solutions they too went black-so that it appeared that this highly reducing factor was a funda- mental constituent of adrenal tissue.