George J. Brewer – författare

Essential and Toxic Trace Elements and Vitamins in Human Health is a comprehensive guide to the wide variety of micronutrients that affect human health, including fat-soluble and water-soluble vitamins that support diverse biochemical functions, trace elements with established and suggested links to health maintenance, and elements with known human toxicity such as arsenic, cadmium, and lead.

An essential reference text for nutritionists working in academia and functional food and supplement industries, dieticians, and clinicians, Essential and Toxic Trace Elements and Vitamins in Human Health provides an in-depth look at toxic trace elements and essential vitamins and minerals and their direct influence on the body's overall health with expert research from renowned scientists.

Presents a balanced scientific view of essential and nonessential micronutrients with an in-depth analysis of the biochemical functions each plays in human health Examines particular micronutrients in detail with coverage of clinical aspects, interaction with other micronutrients, immunological effects, cognitive functions and epigenetics Focuses on effective management of micronutrient deficiencies and on toxicity implications of overexposure

Essential and Toxic Trace Elements and Vitamins in Human Health is a comprehensive guide to the wide variety of micronutrients that affect human health, including fat-soluble and water-soluble vitamins that support diverse biochemical functions, trace elements with established and suggested links to health maintenance, and elements with known human toxicity such as arsenic, cadmium, and lead.An essential reference text for nutritionists working in academia and functional food and supplement industries, dieticians, and clinicians, Essential and Toxic Trace Elements and Vitamins in Human Health provides an in-depth look at toxic trace elements and essential vitamins and minerals and their direct influence on the body''s overall health with expert research from renowned scientists.- Presents a balanced scientific view of essential and nonessential micronutrients with an in-depth analysis of the biochemical functions each plays in human health- Examines particular micronutrients in detail with coverage of clinical aspects, interaction with other micronutrients, immunological effects, cognitive functions and epigenetics- Focuses on effective management of micronutrient deficiencies and on toxicity implications of overexposure

Environmental Causes and Prevention Measures for Alzheimer's Disease examines the increased incidence of the disease in developed countries and aims to educate neuroscientists, medical practitioners and other educated individuals on new insights into environmental causation, primarily metals. This book looks into the web of evidence around the hypothesis of copper toxicity and the additional role that a high fat diet plays in disease progression and cognition loss. The data and its implications are discussed, along with potential prevention measures. This book will generate excitement and interest among neuroscientists, medical practitioners and other biomedical researchers.

Emphasizes the history and epidemiology of Alzheimer's disease, highlighting its epidemic proportions in developed countries Discusses data on new environmental factors in developed countries Provides prevention measures to potentially reduce Alzheimer's rates through diet

Environmental Causes and Prevention Measures for Alzheimer''s Disease examines the increased incidence of the disease in developed countries and aims to educate neuroscientists, medical practitioners and other educated individuals on new insights into environmental causation, primarily metals. This book looks into the web of evidence around the hypothesis of copper toxicity and the additional role that a high fat diet plays in disease progression and cognition loss. The data and its implications are discussed, along with potential prevention measures. This book will generate excitement and interest among neuroscientists, medical practitioners and other biomedical researchers.- Emphasizes the history and epidemiology of Alzheimer''s disease, highlighting its epidemic proportions in developed countries- Discusses data on new environmental factors in developed countries- Provides prevention measures to potentially reduce Alzheimer''s rates through diet

Movement disorder specialists, general neurologists, hepatologists, general gastroenterologists, and psychiatrists are the specialists who will most likely see some Wilson's disease patients during their careers. See them - yes. Recognize and diagnose them - maybe. If you are in one of these specialties, and a patient with tremor, hepatitis, cirrhosis, apparent Parkinsonism, or mood disorder, is referred to you, will you appropriately recognize the possibility that the underlying diagnosis may be Wilson's disease? Wilson's disease is both treatable and reversible, and commonly misdiagnosed. This book aims to change this with comprehensive coverage of every aspect of Wilson's disease, from well-catalogued, easy-to-use clinical diagnostic tools to treatment methods to molecular biology. Dr. Brewer is the world's leading expert on Wilson's disease, seeing and caring for over 300 patients with the disease during the last 20 years. He is a professor of human genetics at the University of Michigan.

Movement disorder specialists, general neurologists, hepatologists, general gastroenterologists, and psychiatrists are the specialists who will most likely see some Wilson's disease patients during their careers. See them - yes. Recognize and diagnose them - maybe. If you are in one of these specialties, and a patient with tremor, hepatitis, cirrhosis, apparent Parkinsonism, or mood disorder, is referred to you, will you appropriately recognize the possibility that the underlying diagnosis may be Wilson's disease? Wilson's disease is both treatable and reversible, and commonly misdiagnosed. This book aims to change this with comprehensive coverage of every aspect of Wilson's disease, from well-catalogued, easy-to-use clinical diagnostic tools to treatment methods to molecular biology. Dr. Brewer is the world's leading expert on Wilson's disease, seeing and caring for over 300 patients with the disease during the last 20 years. He is a professor of human genetics at the University of Michigan.

Movement disorder specialists, general neurologists, hepatologists, general gastroenterologists, and psychiatrists are the specialists who will most likely see some Wilson''s disease patients during their careers. See them - yes. Recognize and diagnose them - maybe. If you are in one of these specialties, and a patient with tremor, hepatitis, cirrhosis, apparent Parkinsonism, or mood disorder, is referred to you, will you appropriately recognize the possibility that the underlying diagnosis may be Wilson''s disease? Wilson''s disease is both treatable and reversible, and commonly misdiagnosed. This book aims to change this with comprehensive coverage of every aspect of Wilson''s disease, from well-catalogued, easy-to-use clinical diagnostic tools to treatment methods to molecular biology. Dr. Brewer is the world''s leading expert on Wilson''s disease, seeing and caring for over 300 patients with the disease during the last 20 years. He is a professor of human genetics at the University of Michigan.

Wilsons Disease for the Patient and Family: A Patients Guide to Wilsons disease and Frequently asked Questions about Copper, is an essential reference book for patients with Wilsons disease and their families. In easy-to-understand language, Dr. Brewer, a world authority on Wilsons disease and copper, explains everything about Wilsons disease, from its genetic cause and mechanism of transmission, to effective treatment plans. A comprehensive glossary provides readers with definitions and explanations for many of the scientific words and phrases used in the text.Major reasons why this book is important to patients relate to the rarity of the disease, variation in its manner of presentation, and the likelihood that doctors consulted about the medical problems will know very little about Wilsons disease. Most doctors, even specialists in liver disease or neurology, will see at most one or two cases during their entire medical careers. If patients hope for rapid and early diagnosis, and that is important to preserve as much function as possible, they may need to help the doctor think of the disease in the first place, and help in sorting out what constitutes proper diagnosis. And then, if there is a diagnosis, comes treatment. The days are gone when one drug, penicillamine (the only anticopper drug most doctors have heard of), is prescribed as soon as the diagnosis is made. Now we have different therapies for different stages. In fact, we no longer recommend penicillamine for Wilsons disease at all. This book will guide the patient and family through all of these various aspects of Wilsons disease.Dr. Brewer begins by describing Wilsons disease, what causes it, how it is inherited, and what symptoms people with Wilsons disease exhibit. It is an inherited disorder of copper accumulation and toxicity, affecting one in 40,000 people worldwide. After basic coverage of Wilsons disease, Dr. Brewer devotes an entire chapter to answering some of the most commonly asked questions about copper. Many of these questions are unrelated to Wilsons disease, but are questions frequently asked by other types of patients as they are informed that there is something wrong with their copper. After that, Dr. Brewer explores the symptoms which should trigger the suspicion of Wilsons disease, and what screening tests can be done to explore this possibility. He then covers testing which will give a definitive diagnosis, what the results of different tests mean, and some of the possible problems with various tests which might be performed. Once a reliable diagnosis of Wilsons disease is made, anticopper therapy is essential to the survival of Wilsons disease patients. Dr. Brewer explains what drugs are available for treatment of Wilsons disease, and offers a comparison of their benefits and side effects. He elaborates on variations in treatment, first discussing the initial stage of treatment, and then long-term maintenance therapy. Included in the discussion are tips for treatment of children and pregnant women. The risks and long-term outlook for a person diagnosed with Wilsons disease are discussed in some detail. After these information-packed chapters, Dr. Brewer devotes a chapter to answering some frequently asked questions about Wilsons disease, and presents resources available to Wilsons disease patients and their families. The book concludes as Dr. Brewer examines the current shortcomings in Wilsons disease therapy, and points to areas which might be improved upon in the future.

As most everyone who reads the newspapers these days will be aware, DNA technology and cloning genes (isolating and obtaining the DNA for a specific gene) is on the cutting edge of science. Almost every week a new gene is cloned, its DNA sequence determined, and its function discovered. Discoveries of genes that cause specific diseases, even some cancers (such as breast cancer), are being made on a regular basis. The gene that is discovered in the present story is, at present, fictional. It is a gene that promotes the aging process, and therefore, it promotes death. The flip side of the gene is that if its action is turned off by a new drug, as it is in the story, it stops aging and allows an unlimited life-span. Neither the discovery of such a gene, or its manipulation by a drug, are at all far-fetched. In fact, it can be anticipated that such a gene probably will be discovered sooner or later. This is a story about what happens when such a gene, and a way to turn it off, are discovered.Story LineIt all started with something seemingly trivial, the interruption of the usual behavior of the pet mice in Dr. Al Grogans laboratory. A world-class physician-scientist in his mid-fifties, Grogan has been spending long evenings in his lab and office trying to solve a riddle. Why had one of his discoveries, a promising new long-acting contraceptive called DNA-C129, quit working? The unusual squeaks and sounds of protest from the mice interrupted Grogans concentration.The reason the mice are disturbed is obvious. Maria, Grogans new lab assistant, an attractive lady in her late thirties, has disturbed the mice by peering closely at them. Initially disgruntled at the interruption, Grogan nevertheless demonstrates to Maria a trick he had taught the mice. Maria asks about the age of the mice and Grogan says theyre maybe four years old, since they were part of the original DNA-C129 experiments. Maria, who has had considerable experience studying mouse aging, contradicts her boss, saying that mice of this strain simply dont live that long. In human terms, they would be the equivalent of two-hundred years old!Grogan, who now realizes he isnt very well-informed about mouse life-span, tells Maria he was probably mistaken about the age of the mice. But he knows they are really about four years old, and his mind starts churning excitedly about some of the possible effects of DNA-C129, and about the reason it may have stopped working. With this new clue, things begin to snap into place in Grogans mind. DNA-C129 had quit working when he had lost his junior partner, a younger man named Bowdler, who had been carrying out the actual experiments under Grogans general supervision. Bowdler had been killed in an auto accident. Grogan now realizes that DNA-C129 has antiaging properties, and probably owes its long-lasting effects to Bowdler doing an outlaw experiment, namely using an illegal vector (the viral-like particle that delivers the therapy DNA), one that had not been authorized by Grogan. The keys to DNA-C129 effects, including its antiaging effects, no doubt lay not only in its own innate properties, but in the vector Bowdler had used. With Bowdlers death, and with Grogan now using the standard vector, DNA-C129 had lost its properties in Grogans experiments.During the next four months the Grogan lab becomes a beehive of activity as Grogan sets out to test these ideas. As the work goes on, a romance develops between Grogan and Maria. However, Grogan is very secretive about the purpose of the experiments, even with Maria. He works for a modest-sized biotech company, in Madison, Wisconsin, called DNA Unlimited, and he doesnt trust management. He codes all the results, and mixes up the experiments in such a manner that no single technician has a complete picture of the studies and the results.During this time Grogan places regular calls to a former student, and current best friend, Kirk Starge

Peter Faulkner, a graduate student in microbiology, called his wife to tell her hed be late, and made the mistake of calling from his mentors office. Catching Peter in his presumably locked office when he returned unexpectedly, Professor Jergens was enraged, mistakenly thinking Peter had seen secret material. The Professors suspicions set in motion a series of events that, before they had run their course, led to numerous deaths that seemed to be due to some mysterious poison or infection. Peter found himself in the middle, accused of the murders, and fighting for his life to try to solve the mystery of what was causing the deaths. The agent was extremely mysterious, killing but leaving no trace of itself. Could Peter solve the mystery of this deadly agent, while being hounded by powerful and sinister forces that didnt want this secret exposed?

George Brewer is a physician and Professor of Human Genetics and Internal Medicine at the University of Michigan Medical School. His research has touched on many diverse fields of medicine and genetics, and led to extensive publications in the medical literature. Recently, he has turned his attention to writing medical thrillers, such as The Bloodcicle Agent, which push a scientific idea a little beyond the envelope of current capability, and then builds a story around these new developments. Besides The Bloodcicle Agent, Dr. Brewer has written two other medical thriller novels, The Death Gene and I.D., and an autobiography, From Start to Finish, which are also published by Xlibris.