George M. Baer – författare

The Natural History of Rabies, Volume I explores the fundamental aspects of the rabies virus, including its growth, latency, morphology, chemistry, physical characteristics, and relationships with other viruses. It looks at the virus'' in vivo pathogenesis and pathology, from entrance to transmission in the central nervous system (CNS) and subsequent exit. It also reviews current diagnostic methods including those used for antibody titration and for determination of virus presence.Organized into three sections encompassing 21 chapters, this volume begins with an overview of the history of rabies as well as its morphology and morphogenesis. It then discusses the virus'' antigenic composition and relationships, hemagglutinin and the optimal conditions for its preparation and demonstration, advantages and disadvantages of the passive hemagglutination test, methods for concentration and purification of the virus, and growth in cell culture. It explains the virus'' pathogenesis to and spread within and from the CNS, electron microscopy of CNS and extraneural rabies infection, lipotropism in rabies virus infection, use of exogenous and endogenous interferon to inhibit rabies virus infection, mouse inoculation and Negri body diagnosis, and fluorescent antibody test in rabies. The book concludes with an assessment of the serum neutralization, indirect fluorescent antibody, and rapid fluorescent focus inhibition tests.This book is a valuable resource for virologists, pathologists, epidemiologists, and students.

This book provides essential worldwide reference information regarding rabies for public health officials, veterinarians, physicians, virologists, epidemiologists, infectious disease specialists, laboratory diagnosticians, and wildlife biologists. The book is divided into six main sections, covering topics such as the rabies virus, including antigenic and biochemical characteristics; pathogenesis, including the immune response to the infection, pathology, and latency; diagnostic techniques; rabies epidemiology in a variety of wild and domestic animals; rabies control, including vaccination of wild and domestic animals, as well as control on the international level; and finally a discussion of rabies in humans, local wound and serum treatment, and human post-exposure vaccination. Natural History of Rabies, First Edition has been the principal worldwide reference since 1975. The new Second Edition has been completely updated, providing current information on this historically deadly disease.

This book provides essential worldwide reference information regarding rabies for public health officials, veterinarians, physicians, virologists, epidemiologists, infectious disease specialists, laboratory diagnosticians, and wildlife biologists. The book is divided into six main sections, covering topics such as the rabies virus, including antigenic and biochemical characteristics; pathogenesis, including the immune response to the infection, pathology, and latency; diagnostic techniques; rabies epidemiology in a variety of wild and domestic animals; rabies control, including vaccination of wild and domestic animals, as well as control on the international level; and finally a discussion of rabies in humans, local wound and serum treatment, and human post-exposure vaccination. Natural History of Rabies, First Edition has been the principal worldwide reference since 1975. The new Second Edition has been completely updated, providing current information on this historically deadly disease.