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4 produkter
4 produkter
2 180 kr
Skickas inom 10-15 vardagar
2 180 kr
Skickas inom 10-15 vardagar
2 180 kr
Skickas inom 10-15 vardagar
Written by experts in the field, Biomarkers in Breast Cancer presents an updated view on the prognostic and predictive biomarkers in breast cancer covering the major advancements in the application of the novel sophisticated molecular methods as well as the conventional state-of-the art prognostic and predictive indicators. This text offers a critical view on the modern approach to the development of surrogate biomarkers of prognosis and responsiveness to selective treatments in breast cancer.
2 180 kr
Skickas inom 10-15 vardagar
Expert laboratory and clinical researchers from around the world review how to design and evaluate studies of tumor markers and examine their use in breast cancer patients. The authors cover both the major advances in sophisticated molecular methods and the state-of-the-art in conventional prognostic and predictive indicators. Among the topics discussed are the relevance of rigorous study design and guidelines for the validation studies of new biomarkers, gene expression profiling by tissue microarrays, adjuvant systemic therapy, and the use of estrogen, progesterone, and epidermal growth factor receptors as both prognostic and predictive indicators. Highlights include the evaluation of HER2 and EGFR family members, of p53, and of UPA/PAI-1; the detection of rare cells in blood and marrow; and the detection and analysis of soluble, circulating markers.