Graham L. Patrick – författare

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6 produkter

Antimalarial Agents

Design and Mechanism of Action

AvGraham L. Patrick

Häftad, Engelska, 2020

1 948 kr

Skickas inom 10-15 vardagar

Antimalarial Agents: Design and Mechanism of Action seeks to support medicinal chemists in their work toward antimalarial solutions, providing practical guidance on past and current developments and highlighting promising leads for the future.

Malaria is a deadly disease which threatens half of the world's population. Advances over several decades have seen vast improvements in the eff ectiveness of both preventative measures and treatments, but the rapid adaptability of the disease means that the ongoing search for improved and novel antimalarial drugs is essential.

Beginning with a historical overview of malaria and antimalarial research, this book goes on to describe the biological aspects of malaria, highlighting the lifecycle of the parasite responsible for malaria, the problem of resistance, genetic mapping of the parasite's genome, established drug targets, and potential drug targets for the future. This sets the scene for the following chapters which provide a detailed study of the medicinal chemistry of antimalarial agents, with a focus on the design of antimalarial drugs.

Drawing on the knowledge of its experienced authors, and coupling historic research with current fi ndings to provide a full picture of both past and current milestones, Antimalarial Agents: Design and Mechanism of Action is a comprehensive yet accessible guide for all those involved in the design, development, and administration of antimalarial drugs, including student academic researchers, medicinal chemists, malaria researchers, and pharmaceutical scientists.

Consolidates both past and current developments in the discovery and design of antimalarial drugs Presents content in a style that is both thorough and engaging, providing a supportive and guiding reference to students and researchers from interdisciplinary backgrounds Highlights drug targets currently considered to be the most promising for future therapies, and the classes of compounds that are currently being studied and perfected

Introduction to Medicinal Chemistry

AvGraham L. Patrick

Inbunden, Engelska, 1995

1 052 kr

Tillfälligt slut

This illustrated text provides undergraduate and postgraduate students with an accessible introduction to medicinal chemistry. It covers basic principles and background, and then describes the general tactics and strategies employed in developing an effective drug. Through the use of numerous examples, it highlights both the difficulties faced by the medicinal chemist and the great power and potential of rational drug design. This book is suitable for undergraduates on courses in chemistry (2nd and 3rd year) and medicinal chemistry (1st and 2nd year), and postgraduate chemists beginning work in pharmaceutical research.

Beginning Organic Chemistry 1

AvGraham L. Patrick

Häftad, Engelska, 1997

535 kr

Skickas inom 5-8 vardagar

The first of two workbooks through which students entering first year university courses can gain confidence in organic chemistry, this text will also be of use in A-level courses, and Higher and Sixth Year Study Courses in Chemistry. Designed to challenge the student to test his or her knowledge, each section leads the student through the subject matter by giving a short piece of theory, followed by a question. Space is then provided for the student's answer and the full model answer is given - encouraging thought about what is being read at all times. Areas covered include drawing structures, functional groups and formulae and molecular weights. Later sections covering such aspects as isomers, non equivalent carbon and hydrogen atoms, and stereochemistry will be relevant to most parts of University courses in organic chemistry and are necessary pre-requisites before effective progress can be made to Beginning Organic Chemistry 2 - Workbook.

Beginning Organic Chemistry 2

AvGraham L. Patrick

Häftad, Engelska, 1997

535 kr

Skickas inom 5-8 vardagar

Following on from Patrick's Beginning Organic Chemistry 1, this workbook developes the concepts raised in the first Workbook and will be complimentary to most organic chemistry textbooks.

An Introduction to Drug Synthesis

AvGraham L. Patrick

Häftad, Engelska, 2015

774 kr

Skickas inom 5-8 vardagar

An Introduction to Drug Synthesis explores the central role played by organic synthesis in the process of drug design and development.Written by an experienced and talented author to complement his existing An Introduction to Medicinal Chemistry, the book illustrates how organic synthesis makes important contributions throughout the drug design and discovery process - from the generation of novel drug structures to the improved efficiency of large scale synthesis.Avoiding excessively detailed descriptions of the underlying synthetic pathways, the book focuses on how synthesis can be used in a strategic way - how and why different synthetic approaches are adopted, and the pros and cons of each. With examples used extensively to illustrate the concepts presented, An Introduction to Drug Synthesis> is the ideal resource for any pharmaceutical or medicinal chemistry student who needs a thorough understanding of how the concepts of organic synthesis are applied to the development of therapeutic drugs.Online ResourcesAn Introduction to Drug Synthesis is supported by online resources featuring:For registered adopters:- Figures from the book in electronic format;For students:- A suite of multiple-choice questions to support the learning process;- Additional case studies- More detailed descriptions of key synthetic reactions, as a source of further reference.

An Introduction to Medicinal Chemistry

AvGraham L. Patrick

Häftad, Engelska, 2023

797 kr

Skickas inom 5-8 vardagar

Medication is widely used to support the human body to fight against infection and pain. In an era of pharmaceutical and medicinal challenges, we have all become more familiar with drug production and distribution. However, do we really know what happens before those drugs are distributed? What's the process behind drug discovery? How do our bodies interact with those chemicals? An Introduction to Medicinal Chemistry, 7th edition, offers a complete and accessible approach to this multidisciplinary field. Its student-friendly writing style makes this text an ideal tool for those coming to the subject for first time, but also for students looking to deepen their understanding.The book guides students through understanding the principles of drug action targets in Part A, to how drugs interact at a molecular level with our organs to offer therapeutic value in Part B, and exploring drug design and discovery, as well as regulatory procedures in Part C. Offering a practical approach, Part D provides a deeper look at specific tools and techniques of medicinal chemistry, concluding with emerging topics including antibodies and anticancer agents in Part E. From principles to practice, accompanied by examples and case studies emerging from current biomedical research, the book will equip students with a robust understanding of medicinal chemistry, to prepare them for future success.

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Graham L. Patrick – författare

Antimalarial Agents

Introduction to Medicinal Chemistry

Beginning Organic Chemistry 1

Beginning Organic Chemistry 2

An Introduction to Drug Synthesis

An Introduction to Medicinal Chemistry

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