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3 produkter
554 kr
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The majority of stroke syndromes are caused by thrombotic occlusion of the cerebral arteries. Timely dissolution of blood clots by intravenous or intra-arterial infusion therefore might be a logical treatment strategy for acute thrombotic or embolic stroke. This volume gives an account of the present diagnostic approaches in acute thrombotic and thrombembolic stroke and the rationale for the use of thrombolytic agents in acute stroke. The most dangerous possible side effect of this treatment strategy, haemorrhage, is carefully discussed. Particular attention is paid to the latest developments in thrombolytic drugs. The results of all major safety and efficacy trials on thrombolytic therapy in stroke are also presented.
1 101 kr
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Over the last decade, interest in the treatment of ischemic stroke has increased significantly. Perhaps the single most important feature of attempts to improve the outcome of stroke patients has been the interventions applied within the very early hours of stroke symptoms. This has spawned efforts to understand the vascular and neuronal responses to cerebral artery reperfusion experimentally. Important prospective clinical studies of thrombolysis in acute ischemic stroke have been completed, and large placebo-controlled, symptom-based studies are now underway worldwide. This book considers the central features of those studies, their experimental basis and the future importance of adjunctive therapies to brain ischemia. Risks and benefits are discussed.
1 101 kr
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On the threshold of an exciting new era for acute stroke diagnosis and treatment, the Third International Symposium on Thrombolytic Therapy in Acute Ischemic Stroke was held in Nara, Japan, in April 1994. The symposium brought together some 200 basic and clinical scientists for presentations and discussions of issues vital to the understanding of thrombolytic therapy. This volume compiles the major presentations of the symposium, with attention to applications of new diagnostic measures such as diffusion and perfusion MRI, contrast-enhanced transcranial Doppler and angioscopy. Other presentations examine the mechanisms of ischemia/reperfusion injury, hemorrhagic transformation, and reocclusion, with reviews of recent developments in thrombolytic agents. The proceedings of the symposium will be of special interest to researchers, physicians, and students in the fields of neurology, neurosurgery, and nuclear medicine, as well as those in pharmacology, critical care medicine, and related fields.