Guido N. J. Tytgat – författare

The explosion of information on Helicobacter pylori-related disease, both in the basic sciences and in clinical medicine, has continued to progress at an unprecedented pace. In many instances H. pylori infection, both in man and in the laboratory animal, has become a model to investigate fundamental biological issues such as micro-organism host interactions, intracellular signalling, development of mucosal atrophy, mechanism of microbial resistance, disease modifying factors etc. In view of this bewildering flood of information, another meeting on H. pylori in the successful series "Basic mechanisms to clinical cure" was organized in January 1998 in San Diego, California, to define the "state-of-affairs" in H. pylori research at this time. The main objective was to integrate this information in a series of presentations and discussions between investigators and clinicians addressing all aspects of H. pylori research and to review the current position and future research directions. The format included presentations by world experts heavily involved in H. pylori research followed by in-depth discussion on intriguing or controversial issues.The presentations were grouped according to the leading theme: characteristics of the organism, mode of transmission, mechanisms of H. pylori-induced inflammation, causation of disturbances of gastric secretory and motor function, aspects of clinical presentation and management, problems related to H. pylori-associated gastric adenocarcinoma and MALT-lymphoma, novel aspects of antimicrobial therapy and vaccination. The chapters published in these proceedings accurately reflect the content of the presentations. These proceedings are testimony to the impact on basic science and clinical medicine of the H. pylori discovery.

The book contains chapters by a multidisciplinary, international group of basic scientists and clinical investigators who focus on various microbiological aspects of Heliobacter pylori, its role in peptic ulcer and gastric cancer, and the current status of therapy.

Staging and grading are indispensable in reaching an adequate diagnosis, to determine disease severity, to choose an appropriate therapy, and to assure the best patient care and quality of life, but up to now no one source in gastroenterology has existed. Gastroenterologists, gastrointestinal surgeons, and fellows-in-training in gastroenterology will therefore immediately recognize the practical value of Grading and Staging in Gastroenterology - a comprehensive and systematic overview of all the current and most relevant information regarding grading and staging in gastroenterology - now selected and compiled for the first time in a single volume.

Organized into three sections - Instruments for Overall Patient and Disease Assessment ; Organ and Disease-related Staging and Grading Systems, and Quality of Life Patient Assessments - readers have the option of using as an overall reference, to refer to a specific organ or disease, or by virtue of the extensive subject index, to research according to specific instrument or other relevant topics.

The following timesaving and didactic features further enhance the usefulness, and whether you are a clinician or surgeon, responsible for training, involved in research including setting up research trials, or require deeper understanding of evidence-based studies you will find making this compendium a part of your gastroenterology library a smart investment.

Uniform presentation -- each of the grading and staging systems is anchored in a strict text structure which includes aims, comments, and exact reference Precise and unobtrusive explanatory notes (comments) -- especially useful for nurse practitioners Numerous supplementary, high-quality line drawings, and endoscopic, radiologic and histological images -- clarify and elucidate where appropriate Complete and accurate reference of all original sources respective to each instrument -- saves valuable research time

Grading and Staging in Gastroenterology is for all gastrointestinal professionals looking for an ideal guide into the myriad of staging and grading systems in gastroenterology.