Hans E. Kaiser – författare
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Childhood brain tumors are a diverse group of diseases characterized by the abnormal growth of tissue contained within the skull. Other than leukemia and lymphoma, brain tumors are the most common type of neoplasms that occur in children. The leading cause of death from childhood neoplasms among persons up to 19 years is brain tumors. As such, this book is a review of the most recent molecular biological research concerning brain tumors with references and comparisons to a variety of neoplastic disorders. The book then uses this information to foreshadow the direction that future anti-neoplastic therapies will take. Because of the wide spectrum of the objectives of the book, any individual involved in cancer research will greatly benefit from the work. Histopathologists, neuropathologists, clinical and research oncologists, and medical students will find this book to be an invaluable resource as a reference guide. Patients and their families will also find the book useful as it offers a comprehensive update on new, non-classical therapeutic modality options and contains a detailed description and analysis of brain tumors. Such an endeavor has yet to be undertaken by any other book and may prove to be the most comprehensive book on brain tumors thus far.
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The processes of tumor metastasis, apoptosis and anti-tumor immune response are among the most complex yet rapidly advancing fields in the area of cancer research. This monograph presents a comprehensive coverage of the recent advances in the various key concepts in these fundamental aspects of human cancer. It would be of particular interest to members of the cancer research community, especially those who are actively involved in the study of basic and translational aspects of human cancer. Specifically, this volume includes authentic subject reviews by leading experts on the following aspects:
Control of tumor cell motilityRole of tumor-cell adhesion and migration in organ-selective metastasis-formationTumor heterogeneity in relation to invasion and metastasis and its clinical implicationsTumor angiogenesis, angioprevention, anti-angiogenic therapies and responseRole of apoptosis in the development, progression and therapy of cancerRole of macrophages in tumor development and metastasisPathways of macrophage-mediated tumor progressionAbnormal variation of immune response against cancerImmunological aspects of Marek’s disease virus (MDV)-induced lymphoma progressionA biodynamical model of human T-cell proliferative disordersCurrent methodologies for characterization of tumor directed immune response.1 681 kr
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Comparative Aspects of Tumor Development
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