Hermann Ehrlich – författare

Das Buch

Das Werk ist eine Quelle für modernes Wissen über Biomineralisation, Biomimetik und bioinspirierte Materialwissenschaft in Bezug auf wirbellose Meerestiere. Der Autor liefert die kohärenteste Analyse der Natur, des Ursprungs und der Entwicklung von Biokompositen und Biopolymeren, die aus der großen Vielfalt der wirbellosen Meeresorganismen isoliert und in deren ungewöhnlichen Strukturformationen beobachtet wurden. Das grundlegende Format ist das eines großen Übersichtsartikels, mit großzügiger Verwendung von Verweisen auf die Originalliteratur. Das Buch enthält eine Fülle neuer und neu zusammengestellter Informationen, darunter Dutzende von bisher unveröffentlichten Bildern einzigartiger mariner Lebewesen und Strukturen vom Nano- bis zum Mikrobereich, einschließlich hochauflösender Raster- und Transmissionselektronenmikroskopaufnahmen. Das Material ist sowohl nach biologischen (Phyla) als auch nach funktionellen Gesichtspunkten geordnet. Es wird eine Klassifizierung der biologischen Materialien marinen Ursprungs vorgeschlagen und diskutiert. Ein Großteil der einschlägigen Daten ist in Tabellen organisiert, und es wird ausgiebig Gebrauch von elektronenmikroskopischen Aufnahmen und Strichzeichnungen gemacht. Mehrere moderne Themen, wie z.B. "Biomineralisierungs-, Demineralisierungs- und Remineralisierungsphänomene" oder "Phänomene der mehrphasigen Biomineralisation", werden ausführlich diskutiert. Traditionell werden aktuelle Konzepte wie die hierarchische Organisation von Biokompositen und Skelettstrukturen, strukturelle Biogerüste, Bioskulpturierung, Biomimetismus und Bioinspiration als Werkzeuge für das Design innovativer Materialien sowohl aus biologischer als auch aus materialwissenschaftlicher Sicht anhand zahlreicher einzigartiger Beispiele marinen Ursprungs kritisch analysiert. Diese Monographie gibt einen Überblick über die wichtigsten Fortschritte auf dem Gebiet der marinen Biomaterialien und zeigt mehrere Ansätze auf, die von verschiedenen Labors eingeführt und erforscht werden."

This book discusses the current direction of the research approach to extreme biomimetics through biological materials-inspired chemistry and its applications in modern technology and medicine. It  is a resource covering topics of extreme (psychrophilic and thermopilic) biomineralization, solvothermal and hydrothermal chemistry of metal oxides and nanostructured composites, and bioinspired materials science in a diverse areas. The authors review the current advances in the extreme biomimetics research field and describe various approaches introduced and explored by their respective laboratories.

• Details the basic principles of extreme biomimetics approach for design of new materials and applications;

• Includes numerous examples of the hierarchical organization of hydrothermally or psychrophilically obtained biocomposites, structural bioscaffolds, biosculpturing, biomimetism, and bioinspiration as tools for the design of innovative materials;

• Describes and details the principles of extreme biomimetics with respect to metallization of chemically and thermally stable biopolymers.

The work is a source of modern knowledge on biomineralization, biomimetics and bioinspired materials science with respect to marine invertebrates. The author gives the most coherent analysis of the nature, origin and evolution of biocomposites and biopolymers isolated from and observed in the broad diversity of marine invertebrate organisms and within their unusual structural formations. The basic format is that of a major review article, with liberal use of references to original literature. There is a wealth of new and newly synthesized information, including dozens of previously unpublished images of unique marine creatures and structures from nano- to microscale including high-resolution scanning and transmission electron micrographs. The material is organized effectively along both biological (phyla) and functional lines. The classification of biological materials of marine origin is proposed and discussed. Much of the pertinent data is organized into tables, and extensive useis made of electron micrographs and line drawings. Several modern topics e.g. “biomineralization- demineralization-remineralization phenomena”, or “phenomenon of multiphase biomineralization”, are discussed in details. Traditionally, such current concepts as hierarchical organization of biocomposites and skeletal structures, structural bioscaffolds, biosculpturing, biomimetism and bioinspiration as tools for the design of innovative materials  are critically analyzed from both biological and materials science point of view using numerous unique examples of marine origin. This monograph reviews the most relevant advances in the marine biomaterials research field, pointing out several approaches being introduced and explored by distinct laboratories.

The main focus of this book entitled is to provide an up-to-date coverage of marine sponges and their significance in the current era. This book is an attempt to compile an outline of marine sponge research to date, with specific detail on these bioactive compounds, and their pharmacological and biomedical applications.

The book encompasses twenty chapters covering various topics related to Marine Sponges. Initial couple of chapters deal about the worldwide status of marine sponge research, the recent findings regarding dynamics of sponges, and several interesting research areas, that are believed to be deserving of increased attention. Variety of sponges, their toxicology, metagenomics, pharmaceutical significance and their possible applications in biomedicine has been discussed in detail. The second half of this part includes chapters on chemical ecology of marine sponges followed by the discussion on importance of bioeroding sponges in aquaculture systems. The following four chapters of the book deal majorly with the chemical molecules of marine sponges. In the fifth chapter, marine sponge-associated actinobacteria and their pysicochemical properties have been discussed followed by their bioactive potential. The biological application of marine sponges has been presented in later chapters with the classification of biologically active compounds being explored in detail.

The second half of the book presents the vast repertoire of secondary metabolites from marine sponges, which include terpenoids, heterocycles, acetylenic compounds, steroids and nucleosides. Further, the bioactive potential of these compounds has also been discussed.  One of the constituent chapter elaborates the bioactive alkaloids from marine sponges namely, pyridoacridine, indole, isoquinolene, piperidene, quinolizidine, steroidal and bromotyrosine alkaloids isolated from them. In the next couple of chapters, important sponge polymers and the anticancer effects of marine sponge compounds have been presented.

The most interesting aspect of sponge biology is their use in biomedical arena. An effort has been made in this book, to cover the major constituents of sponges and their biomedical potentials. The major portion of sponge body is composed of collagen and silica and used in tissue engineering as scaffold material. This part of the book compiles chapters delineating the isolation of sponge biomaterials including collagen and their use in medical diagnostics. Overall, this book would be an important read for novice and experts in the field of sponge biology.