Igor Adameyko – författare

Vertebrates possess lineage-specific characteristics. These include paired anterior sense organs and a robust, modular head skeleton built of cellular cartilage and bone. All of these structures are derived, at least partly, from an embryonic tissue unique vertebrates - the neural crest. The evolutionary history of the neural crest, and neural crest cells, has been difficult to reconstruct. This volume will use a comparative approach to survey the development of the neural crest in vertebrates, and neural crest-like cells, across the metazoa. This information will be used to reveal neural crest evolution and identify the genomic, genetic, and gene-regulatory changes that drove them.Key selling features:Summarizes the data regarding neural crest cells and nerural crest derivativesUses a broad-based comparative approachSuggests hypothesis that the origin of neural crest cells involved the novel co-activation of ancient metazoan gene programs in neural border cellsIllustrates how the emergences of neural crest made possible the diversification of vertebrate heads

This book explores the enduring and emerging questions in developmental biology, offering a comprehensive overview that bridges traditional concepts with the innovative inquiries shaping future research. Each chapter delves into a fundamental unresolved questions reflecting the insights of past and the likely vibrancy of future inquiry. These discussions are followed by reviews of novel areas, including mechanobiology, the role of membrane potentials, and the post-transcriptional control mechanisms guiding fate selection and cell differentiation.