J. Marie Hardwick – författare
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2 produkter
2 produkter
Functions, Disease-Related Dysfunctions, and Therapeutic Targeting of Neuronal Mitochondria
Inbunden, Engelska, 2015
2 293 kr
Skickas inom 5-8 vardagar
This book presents advances in the field of neuronal mitochondria – functions, relation to therapeutics, and pharmacology. For scientists and researchers in both industry and academia, this book provides detailed discussion, examples, and approaches, to illustrate the potential of mitochondria as therapeutic targets for neuronal diseases.• Helps readers understand the regulation of mitochondrial cellular processes, such as substrate metabolism, energy production, and programmed versus sporadic cell death• Offers insights on the development of strategies for targeted therapeutic approaches and potential personalized treatments• Includes examples of mitochondrial drugs, development, and mitochondria-targeted approaches for more efficient treatment methods and further developments in the field• Covers the model systems and approaches needed for the development of new drugs for the central nervous system to provide potential modern therapeutics for neurodegenerative disorders
2 902 kr
Kommande
This edited volume discusses the evolution of cell death in microorganisms by providing new theoretical models and experimental studies of microorganisms, both prokaryotes and eukaryotes. It incorporates the latest findings and evidence for bacterial self-destruction, cell-death in multicellular fungi, and potential cell-death mechanisms in unicellular species of algae, parasites, and pathogenic yeast.Mechanisms of self-destruction by individual cells were assumed to arise during evolution with multicellular organisms, which require cell death to generate the complex structures of plants and animals. Current opinion, however, supports an alternative evolutionary history. Arguments from biologists and theorists suggest that programmed cell death likely pre-dates the evolution of multicellular organisms.This volume will prove valuable for microbiologists and cell biologists working in the field of molecular evolution and apoptosis research and might spark new ideas for future applications in science and medicine.