Jack A. Tuszynski – författare

From quantum theory to statistical mechanics, the methodologies of physics are often used to explain some of life''s most complex biological problems. Exploring this challenging yet fascinating area of study, Molecular and Cellular Biophysics covers both molecular and cellular structures as well as the biophysical processes that occur in these structures. Designed for advanced undergraduate and beginning graduate students in biophysics courses, this textbook features a quantitative approach that avoids being too abstract in its presentation.Logically organized from small-scale (molecular) to large-scale (cellular) systems, the text first defines life, discussing the scientific controversies between mechanists and vitalists, the characteristics of living things, and the evolution of life. It then delves into molecular structures, including nucleic acids, DNA, RNA, interatomic interactions, and hydrogen bonds. After looking at these smaller systems, the author probes the larger cellular structures. He examines the cytoplasm, the cytoskeleton, chromosomes, mitochondria, motor proteins, and more. The book concludes with discussions on biophysical processes, including oxidative phosphorylation, diffusion, bioenergetics, conformational transitions in proteins, vesicle transport, subcellular structure formation, and cell division.

From quantum theory to statistical mechanics, the methodologies of physics are often used to explain some of life''s most complex biological problems. Exploring this challenging yet fascinating area of study, Molecular and Cellular Biophysics covers both molecular and cellular structures as well as the biophysical processes that occur in these structures. Designed for advanced undergraduate and beginning graduate students in biophysics courses, this textbook features a quantitative approach that avoids being too abstract in its presentation.Logically organized from small-scale (molecular) to large-scale (cellular) systems, the text first defines life, discussing the scientific controversies between mechanists and vitalists, the characteristics of living things, and the evolution of life. It then delves into molecular structures, including nucleic acids, DNA, RNA, interatomic interactions, and hydrogen bonds. After looking at these smaller systems, the author probes the larger cellular structures. He examines the cytoplasm, the cytoskeleton, chromosomes, mitochondria, motor proteins, and more. The book concludes with discussions on biophysical processes, including oxidative phosphorylation, diffusion, bioenergetics, conformational transitions in proteins, vesicle transport, subcellular structure formation, and cell division.

This book is a collection of stories, reflections and advice written by proficient scientists. They address the question of what doing science means to them, and describe attitudes and working practices that have proved effective and rewarding. The book is aimed in particular at young people who are attracted by science or already undertaking undergraduate studies, and who are considering making science their long-term profession. It will also be helpful and revealing to early-career scientists who are searching for their own best route to success. The book serves as a platform for experienced scientists to describe their original inclination, how that subjective disposition found its expression in their way of doing science, whether their expectations were met, and what achievements they can claim. But it is not restricted to success: contributors also share details of the limitations and failures they have encountered. Last but not least they describe how they see science now, howthey think it will be in the near future, and what advice they would give to the their much younger colleagues. Readers will appreciate the diversity of the individual paths shaped by different education, motivation, ambition, inclination, intuition, feeling, belief and eligibility. At the same time the stories confirm that science relies on a translation of this subjective level into an objective level, one that is shared and accepted by the international scientific community, and whose results are produced with a commonly accepted and fully rational scientific method of investigation.

Consciousness is one of the major unsolved problems in science. How do the feelings and sensations making up conscious experience arise from the concerted actions of nerve cells and their associated synaptic and molecular processes? Can such feelings be explained by modern science, or is there an entirely different kind of explanation needed? And how can this seemingly intractable problem be approached experimentally? How do the operations of the conscious mind emerge out of the specific interactions involving billions of neurons? This multi-authored book seeks answers to these questions within a range of physically based frameworks, i.e, the underlying assumption is that consciousness can be understood using the intellectual potential of modern physics and other sciences. There are a number of theories of consciousness in existence, some of which are based on classical physics while some others require the use of quantum concepts. The latter ones have drawn a lot of criticism from the present-day scientific establishment while simultaneously claiming that classical approaches are doomed to failure. This book presents the reader with a spectrum of opinions from both sides of this on-going scientific debate, letting him/her decide which of these approaches are most likely to succeed.