Jae Jun Song – författare

Nanotechnology in Human Health: Current Research and Future Trends details the various challenges faced in human healthcare settings and how nanotechnology can be used to target and improve outcomes. The book describes the application of nanoparticles in the diagnosis of human diseases, including metabolic diseases, cancer, bacterial infection, organ degeneration and the various targeted, nano-based treatments available. Several chapters look at how microbial biofilms - a key clinical concern - can be mitigated using nanomaterials and nanotechnology. In addition, the book covers how different nanoparticle types can be utilized as therapeutic agents.

This book combines materials science concepts and techniques with clinical insights and understanding to provide an interdisciplinary reference for materials scientists, microbiologists, biomedical engineers and clinicians with an interest in nanotechnology.

Microbial biofilms are serious problem in medical settings as they are associated with significant mortality and morbidity. Infection related to biofilms not only increases recovery time, but also escalates the cost of disease management. Biofilms are intrinsically resistant to antibiotics and evade human defense mechanisms. In addition, the close proximity of microbes within biofilms promotes genetic transformation, facilitating the acquisition of antibiotic-resistant genes and leading to an increased prevalence of diseases associated with resistance. Fortunately, with advances in science and technology, novel strategies are being utilized to mitigate the impact of biofilms on human health.Microbial Biofilms: Role in Human Infectious Diseases focuses on new and emerging concepts in microbial biofilm research. It explores topics such as the mechanisms of biofilm formation, biofilm-induced pathogenesis, biofilm detection and diagnosis, gene exchange within biofilms, strategies to control microbial biofilms, and the burden of biofilm-associated infections. Additionally, the book highlights the various antibiofilm strategies, such as surface coating, signal quenching, novel compounds that can be translated to curb biofilm-associated infections, and the escalation of antimicrobial resistance determinants.