Jagat Narula – författare

Heart transplantation remains one of the major scientific achievements of twentieth century medicine. During the past four decades, it has evolved from an unproven experimental surgical technique to the most effective form of therapy for refractory end-stage heart disease. It has captured the public's imagination and expanded our understanding of fundamental immunologic mechanisms that are responsible for cellular and humorally-mediated immunity. Despite its successes, many clinical and scientific problems remain. One or more bouts of acute cellular or humoral (vascular) rejection will occur in over 75% of transplant recipients despite current immunosuppressive strategies. Further, rejection directly results in approximately 20% of post-transplant deaths and is believed to play a major role in the development of late allograft dysfunction and coronary vasculopathy. This book by international experts in the fields of transplantation medicine, immunobiology and cardiac imaging provides the reader with an up-to-date, consise summary of the latest developments in the diagnosis and treatment of acute cardiac rejection. It is axiomatic that a more complete understanding of the pathogenic processes involved in rejection will ultimately lead to its prevention. This volume will be useful to transplant cardiologists, cardiovascular surgeons, cardiac pathologists and transplant scientists who seek to prolong the lifespan and improve the quality of life of their transplant recipients.

The landmark text that belongs in the hands of every cardiologist―fully updated and reorganized to make it more patient-centric than ever

A Doody's Core Title for 2024 & 2023!

World-famous for its authority and clinical relevance, Fuster and Hurst’s The Heart is cardiology’s longest continuously published reference book. Written to meet the ever-changing needs of cardiologists, fellows, and interns, this trusted classic offers a solid foundation in cardiovascular medicine and complete coverage of all major cardiovascular topics.

This fifteenth edition presents a greater focus on the practicalities of patient care. Additionally, the content is ordered in a more methodical pattern, from mechanism to management. Reflecting the latest technical, therapeutic, and clinical advances, Fuster and Hurst’s The Heart provides invaluable concise summaries of major new trials and guidelines.

Authoritative Coverage and Unmatched Utility:

Central IllustrationsNew section on cardiovascular critical careNew chapter "Cardiovascular Disease and COVID-19"Chapter summariesACC/AHA/ESC guidelines in all chapters1,200+ photos and illustrations

Sections Include:

Risk Factors for Cardiovascular DiseaseAtherosclerosis and Coronary Heart DiseaseDiseases of the Great Vessels and Peripheral VesselsValvular Heart DiseaseRhythm and Conduction AbnormalitiesHeart FailureDiseases of the PericardiumCardiopulmonary DiseaseCritical Cardiovascular CareAdult Congenital Heart DiseaseSpecial Populations and Topics in Cardiovascular Disease

A Doody's Core Title for 2022!

This atlas is a comprehensive visual reference for the use of cardiovascular computed tomography (CT) containing photomicrographs, anatomic illustrations, tables, and charts paired with extensive legends and explanations that are supplemented by extensive research, peer-reviewed articles, and textbooks.In addition to providing historical perspective and current direction for CT, this new edition of ​Atlas of Cardiovascular Computed Tomography 2e focuses on research involving coronary artery diseases and anomalies, congestive heart failure, atherosclerotic plaques and asymptomatic disease, as well as imaging techniques, including preparation, acquisition, and processing, involving the great vessels and carotids, the peripheral vasculature, and coronary and pulmonary veins. The increasing role of CT in the emergency room and in private cardiology practice is also reviewed thoroughly, making this an essential read for all involved in cardiac imaging, cardiology and emergency medicine.​

This atlas is a comprehensive visual reference for the use of cardiovascular computed tomography (CT) containing photomicrographs, anatomic illustrations, tables, and charts paired with extensive legends and explanations that are supplemented by extensive research, peer-reviewed articles, and textbooks.In addition to providing historical perspective and current direction for CT, this new edition of ​Atlas of Cardiovascular Computed Tomography 2e focuses on research involving coronary artery diseases and anomalies, congestive heart failure, atherosclerotic plaques and asymptomatic disease, as well as imaging techniques, including preparation, acquisition, and processing, involving the great vessels and carotids, the peripheral vasculature, and coronary and pulmonary veins. The increasing role of CT in the emergency room and in private cardiology practice is also reviewed thoroughly, making this an essential read for all involved in cardiac imaging, cardiology and emergency medicine.​

Cardiac CT obtains information about coronary arteries, great arteries and veins, and heart valves.� It shows the location and extent of calcified plaque in the coronary arteries and helps detect coronary artery disease at an early stage, which neither traditional imaging techniques nor cardiac testing� can do. Over the last decade technologic advances in CT angiography have been made at a rapid rate, and the new applications and refinements of existing technology continue to be made.� This issue will help practicing cardiologists to keep up with the latest technology in this important and swiftly moving field.

This issue of Medical Clinics of North America provides the latest essential updates on coronary risk factors. The following key questions are answered. Are new biomarkers informative? LDL: the lower the better? How important is HDL? How much credit does triglyceride deserve? How important is family history of coronary disease? How important is age in determining coronary risk factors? Endothelial progenitor cells, menopause, and coronary risk factors? What is the role of imaging in prevention of coronary artery disease? Is genomics ready for primetime? Pediatric statinization? Individualized statinization? Polypill for some, polypill for all?

This volume will be useful to transplant cardiologists, cardiovascular surgeons, cardiac pathologists and transplant scientists who seek to prolong the lifespan and improve the quality of life of their transplant recipients.

The aim of the 4th edition of the Atlas of Nuclear Cardiology is to provide physicians and students in cardiology, radiology, and nuclear medicine who want the latest information in the field of cardiovascular nuclear medicine up-to-date and comprehensive information on advances in instrumentation, radiotracers, protocols, and clinical studies.

This atlas comprehensively covers the use of basic ultrasound (US) scanning technologies to recognize both normal and pathologic states. It covers how to use US for soft tissue diagnosis, assessing cardiac function, pericardial effusion, tamponade, peripheral veins, gallbladder, bowel, kidneys, skull, sinuses, eye, pleura, scrotum and testes. Atlas of Handheld Ultrasound provides detailed clinically relevant examples of how US can be used to aid diagnosis across a wide range of medical disciplines. Chapters are formatted in a clear and easy-to-follow format, with a range of interactive material to aid the reader in developing a deep understanding of how to use and interpret US correctly. It therefore provides a critical resource on how to use the modality for both specialist and non-specialist practitioners.

This atlas provides a detailed visual resource of how sophisticated non-invasive imaging relates to the anatomy observed in a variety of cardiovascular pathologies. It includes investigation of a wide range of defects in numerous cardiac structures. Mitral valve commissures, atrioventricular septal junction and right ventricular outflow tract plus a wealth of other structures are covered, offering readers a comprehensive integrative experience to understand how anatomic subtleties are revealed by modern imaging modalities.Atlas of Non-Invasive Imaging in Cardiac Anatomy provides a detailed set of visual instructions that is of use to any cardiovascular professional needing to understand the orientation of a patient’s imaging. Therefore this is an essential guide for all trainee and practicing cardiologists, cardiac imagers, cardiac surgeons and interventionists.

This atlas provides a detailed visual resource of how sophisticated non-invasive imaging relates to the anatomy observed in a variety of cardiovascular pathologies. It includes investigation of a wide range of defects in numerous cardiac structures. Mitral valve commissures, atrioventricular septal junction and right ventricular outflow tract plus a wealth of other structures are covered, offering readers a comprehensive integrative experience to understand how anatomic subtleties are revealed by modern imaging modalities.Atlas of Non-Invasive Imaging in Cardiac Anatomy provides a detailed set of visual instructions that is of use to any cardiovascular professional needing to understand the orientation of a patient’s imaging. Therefore this is an essential guide for all trainee and practicing cardiologists, cardiac imagers, cardiac surgeons and interventionists.

The fifth edition of this book presents clinical data, image acquisition, and interpretation of nuclear cardiology procedures through high quality illustrative image examples. It includes up-to-date and comprehensive coverage of advances in instrumentation, radiotracers, protocols, and clinical studies. New content includes indications in imaging cardiac sarcoidosis, amyloidosis, and device infections as well as recent advances in instrumentation (Hybrid PET/MR). It also provides fresh chapters on the history of nuclear cardiology imaging, radionuclide handling techniques and radiation safety, PET-based myocardial perfusion imaging, and vascular imaging. The entire field is presented in pictographic form that is visually pleasing and conforming to current trends of medical education. The fifth edition of the Atlas of Nuclear Cardiology is an essential reference for cardiologists, radiologists, and nuclear medicine physicians interested in thelatest approaches to noninvasive diagnostic cardiovascular nuclear imaging techniques.  It also serves as a ready reference textbook for medical students and residents as well as nuclear physicists, nuclear medicine technologists, and radiopharmacists.

The fifth edition of this book presents clinical data, image acquisition, and interpretation of nuclear cardiology procedures through high quality illustrative image examples. It includes up-to-date and comprehensive coverage of advances in instrumentation, radiotracers, protocols, and clinical studies. New content includes indications in imaging cardiac sarcoidosis, amyloidosis, and device infections as well as recent advances in instrumentation (Hybrid PET/MR). It also provides fresh chapters on the history of nuclear cardiology imaging, radionuclide handling techniques and radiation safety, PET-based myocardial perfusion imaging, and vascular imaging. The entire field is presented in pictographic form that is visually pleasing and conforming to current trends of medical education. The fifth edition of the Atlas of Nuclear Cardiology is an essential reference for cardiologists, radiologists, and nuclear medicine physicians interested in thelatest approaches to noninvasive diagnostic cardiovascular nuclear imaging techniques.  It also serves as a ready reference textbook for medical students and residents as well as nuclear physicists, nuclear medicine technologists, and radiopharmacists.

This atlas elucidates the role of the neuronal component in normal cardiovascular function and cardiac disorders and discusses the currently available imaging targets and probes. It provides a foundation in cardiac neuronal imaging and image processing and serves as a guide in the effective utilization of these techniques in clinical and research settings. The atlas discusses the principles of autonomic control in the regulation of cardiac function and disease; chemistry and biology of radiotracers designed to target changes in the myocardial sympathetic and parasympathetic innervation as a function of disease or treatment; neuronal imaging in heart failure and reverse remodeling and the use of PET imaging in quantification of cardiac innervation; cardiac sympathetic innervation in ventricular arrhythmias and device therapy; conditions that affect the autonomic nervous system; and the role of myocardial blood flow and cardiac neuronal imaging in denervation and reinnervation in cardiactransplant recipients. Featuring full-color illustrations, schematic diagrams, and diagnostic algorithms, Atlas of Cardiac Innervation is a valuable resource for cardiologists, radiologists, nuclear medicine physicians, and electrophysiologists.

This atlas is a practical and fully illustrated guide to the use of intravascular OCT in diagnosis and treatment of coronary artery disease. It consists of two parts. The first part of the book provides a systematic introduction to coronary imaging with OCT. It describes how to interpret images and describes abnormal findings seen in atherosclerosis, complications after intervention, and stent assessment. The second part of the book presents real-life case studies that show how OCT is used in clinical practice in Mount Sinai to assess the disease, select appropriate treatment, and evaluate complications and results. Each case includes a brief clinical history, procedure summary, angiography and OCT images, including video material, and a discussion of how OCT affected the clinical decision-making process.

Chapters are formatted in a clear and easy-to-follow format, with a range of interactive material to aid the reader in developing a deep understanding of how to use and interpret US correctly.

This atlas elucidates the role of the neuronal component in normal cardiovascular function and cardiac disorders and discusses the currently available imaging targets and probes. neuronal imaging in heart failure and reverse remodeling and the use of PET imaging in quantification of cardiac innervation;

This atlas is a practical and fully illustrated guide to the use of intravascular OCT in diagnosis and treatment of coronary artery disease. Each case includes a brief clinical history, procedure summary, angiography and OCT images, including video material, and a discussion of how OCT affected the clinical decision-making process.

The book comprises of 142 chapters grouped in 35 sections and exhaustively discusses the role of various imaging modalities in the context of specific diseases, and comparative roles for each modality. The role of echocardiography in the assessment of different types of cardiomyopathy, such as dilated, restrictive and hypertrophic cardiomyopathy, cardiac dyssynchrony, pericardial effusion, oncology, cardiac tamponade and pericardial constriction find good coverage in the book. Advances in echocardiographic assessment of all types of congenital heart disease, including neonatal heart failure are fully discussed.

CVD, or cardiovascular disease, is a general term that describes a disease of the heart or blood vessels. It is one of the most common causes of death.Statins are a group of medicines that can help lower the level of low-density lipoprotein (LDL) cholesterol in the blood. LDL cholesterol of often referred to as ‘bad cholesterol’, and statins reduce its production in the liver. Having a high level of LDL is potentially dangerous as it can lead to  hardening and narrowing of the arteries (NHS).Comprising nearly 1000 pages, this book is a comprehensive guide to the latest advances in statin therapy and its clinical application for cardiovascular disease.Divided into 29 sections, the text begins with clinical aspects of CVD, dyslipidemia (the imbalance of lipids such as cholesterol), and the use of statins for treatment.The next sections provide detailed discussion on the use of statins for different types of CVD, including coronary artery disease, hypertension, heart failure, arrhythmia, stroke, and more.The following chapters cover statin use for other systemic diseases such as obesity, kidney disease, diabetes, ocular disorders, skin conditions and many more.The book concludes with an insight into future therapies, with emphasis on PCSK9 inhibitors, a new treatment for lowering cholesterol in the blood.

HFpEF, or Heart Failure with preserved ejection fraction, is a type of heart failure where the heart's main pumping chamber (the left ventricle) becomes too stiff to fill properly with blood, even though it can still contract normally. This leads to symptoms like breathlessness, fatigue, and swelling due to blood and fluid backing up in the lungs and body. HFpEF is often associated with other conditions such as high blood pressure, diabetes, obesity, and heart disease, and treatment focuses on managing these underlying factors and relieving symptoms.Based on the experience of more than 300 contributors, this book is a comprehensive guide to the diagnosis and management of HFpEF, explaining advances in clinical approach, imaging including echocardiography, and multimodality imaging; and drug, mechanical and surgical interventions.Comprising 21 sections and169 chapters, as many as 28 chapters in this book deal with echocardiography and HFpEF. Assessment of HFpEF using echocardiographic techniques such as three-dimensional echocardiography and more recent advances such as speckle tracking of echocardiography for assessment of left ventricular, left atrial, right ventricular, and right atrial strain, are covered in depth.Discussion on echocardiographic ventricular and atrial remodeling reversal with various therapeutic agents, including sodium‐glucose cotransporter‐2 (SGLT2) inhibitors, angiotensin receptor–neprilysin inhibitor (ARNI), and bisoprolol, is included.Exercise-induced left atrial hypertension in HFpEF and the effect of various therapeutic agents on left atrial stiffness index, left atrial function, and other left ventricular diastolic parameters are also examined.

Heart failure is a serious condition caused by the heart failing to pump enough blood around the body at the right pressure. It usually occurs because the heart muscle has become too weak or stiff to work properly, most commonly caused by heart attack, high blood pressure or cardiomyopathy (heart disease).This textbook is a comprehensive guide to the latest advances in the diagnosis and management of heart failure.Comprising nearly 1000 pages, the book features 15 sections, beginning with discussion on clinical issues of heart failure, followed by imaging techniques.Each of the following sections covers a different disorder or disease that subsequently may lead to heart failure. Topics include coronary artery disease, stroke, arrhythmia, hypertension, nutritional aspects, cardio-oncology, and much more.The book concludes with rehabilitation, legal aspects, and future directions.Authored by internationally recognised experts in the field, the text is further enhanced by clinical photographs, diagrams and tables.Key pointsComprehensive guide to latest advances in diagnosis and management of heart failureExtensive text comprising nearly 1000 pages covering numerous associated disorders and diseasesInternationally recognised editor and author teamHighly illustrated with clinical photographs, diagrams and tables