James D. Cox - Böcker

The animal care and use facility support - or cage wash - area has evolved tremendously in the past fifty years. It is now recognized as a critical component in programs of animal care and use throughout the world, yet there has previously been no single, comprehensive resource to support it. This much-needed book describes facility support operations that have a direct, substantial effect on the program’s ability to provide quality animal care. Editors James D. Cox and Bruce W. Kennedy, practitioners with more than 80 years of experience in laboratory animal facilities between them, show how cage wash serves as the hub of the entire research animal enterprise. After all, when cage wash comes to a halt, there are no clean cages or equipment, and research struggles to continue. There is a significant volume of knowledge necessary to work in facility support roles, spread across many different resources, many of which are unpublished and/or at a highly skilled technical level. This book brings all the relevant information together in an accessible, highly practical guide. By increasing staff knowledge and skills in the operation, maintenance, and troubleshooting of equipment, the book shows that cage wash can be a viable career path, especially as facilities increasingly depend on different types of automation.

Lung cancer is the leading cause of cancer death in the United States, but IGRT (image guided radiation therapy) offers the possibility of more aggressive and enhanced treatments. The only available source on the subject that emphasizes new imaging techniques, and provides step-by-step treatment guidelines for lung cancer, this source helps clinicians locate and target tumors with enhanced speed, improve the accuracy of radiation delivery, and correctly target cancerous masses while avoiding surrounding structures.Edited by radiation oncology experts from the renowned M.D. Anderson Cancer Center, this guide: focuses on novel approaches using IGRT, particularly PET/CT, SPECT, 4-D CT, stereotactic body radiation therapy, IMRT and proton radiotherapy, and offers expert guidance on the dose, fractionation, target volume delineation (including recommended margins with and without respiratory gating based on our new 4-D CT study), and normal tissue tolerancesstands as the first step-by-step guide for radiation oncologists to implement new image-guided techniques into their day-to-day clinical practice, and considers the practical issues of implementing these approaches into their routinehelps clinicians use imaging technologies to detect changes in tumor size, shape, position, or metabolism over a course of radiotherapy treatmentprovides disease stage-specific treatment guidelines and clearly lays out imaging techniquesserves as roadmap for future research and development