James G. Fujimoto – författare

Biomedical optical imaging is a rapidly emerging research area with widespread fundamental research and clinical applications. This book gives an overview of biomedical optical imaging with contributions from leading international research groups who have pioneered many of these techniques and applications. A unique research field spanning the microscopic to the macroscopic, biomedical optical imaging allows both structural and functional imaging. Techniques such as confocal and multiphoton microscopy provide cellular level resolution imaging in biological systems. The integration of this technology with exogenous chromophores can selectively enhance contrast for molecular targets as well as supply functional information on processes such as nerve transduction. Novel techniques integrate microscopy with state-of-the-art optics technology, and these include spectral imaging, two photon fluorescence correlation, nonlinear nanoscopy; optical coherence tomography techniques allow functional, dynamic, nanoscale, and cross-sectional visualization. Moving to the macroscopic scale, spectroscopic assessment and imaging methods such as fluorescence and light scattering can provide diagnostics of tissue pathology including neoplastic changes. Techniques using light diffusion and photon migration are a means to explore processes which occur deep inside biological tissues and organs. The integration of these techniques with exogenous probes enables molecular specific sensitivity.

Biomedical optical imaging is a rapidly emerging research area with widespread fundamental research and clinical applications. This book gives an overview of biomedical optical imaging with contributions from leading international research groups who have pioneered many of these techniques and applications. A unique research field spanning the microscopic to the macroscopic, biomedical optical imaging allows both structural and functional imaging. Techniques such as confocal and multiphoton microscopy provide cellular level resolution imaging in biological systems. The integration of this technology with exogenous chromophores can selectively enhance contrast for molecular targets as well as supply functional information on processes such as nerve transduction. Novel techniques integrate microscopy with state-of-the-art optics technology, and these include spectral imaging, two photon fluorescence correlation, nonlinear nanoscopy; optical coherence tomography techniques allow functional, dynamic, nanoscale, and cross-sectional visualization. Moving to the macroscopic scale, spectroscopic assessment and imaging methods such as fluorescence and light scattering can provide diagnostics of tissue pathology including neoplastic changes. Techniques using light diffusion and photon migration are a means to explore processes which occur deep inside biological tissues and organs. The integration of these techniques with exogenous probes enables molecular specific sensitivity.

Optical coherence tomography has become a part of clinical routine in everyday eye practice, allowing objective, quantitative structural assessment and driving clinical decision making in retinal diseases, glaucoma and cataract surgery. To guide the eyecare professionals who rely on this technology, Everyday OCT: A Handbook for Clinicians and Technicians, Second Edition is a user-friendly, practical reference that provides all of the information they need to know about current OCT technologies and their clinical utilities. Drs. Joel S. Schuman, Carmen A. Puliafito, James G. Fujimoto, and Jay S. Duker represent the cutting edge of OCT applications and, together with their expert contributing authors, they have created a clear and concise guide designed to provide clinicians and technicians with the knowledge and tips to best utilize OCT technology. This Second Edition is split into three parts: an operational guide with in-depth guidance and tips on the six major OCT devices from six different manufacturers, an interpretation guide featuring all the major pathologies OCT can visualize, and a technical guide containing detailed technical aspects of the SD-OCT and the future of OCT technologies.Everyday OCT, Second Edition explains how to: Set up and employ OCT technology Select and facilitate scans Ensure and assess the quality of scans Accurately interpret OCT images Everyday OCT: A Handbook for Clinicians and Technicians, Second Edition covers the diversity of new devices and applications in the field of OCT in a succinct and easy-to-read format, making it the ideal resource for clinicians and technicians to have by their side when performing or interpreting OCTs.

The most comprehensive text and definitive guide for nearly 30 years about optical coherence tomography (OCT) imaging in ophthalmology, Optical Coherence Tomography of Ocular Diseases, Fourth Edition covers a range of subjects, from principles and operation techniques to clinical interpretation and the latest innovations in OCT. Written by the pioneers of OCT technologies and the world-renowned OCT researchers Drs. Joel S. Schuman, James G. Fujimoto, Jay S. Duker, Hiroshi Ishikawa, and Gadi Wollstein, Optical Coherence Tomography of Ocular Diseases, Fourth Edition is an essential text for imaging technology.OCT now occupies a dominant role as a diagnostic tool for retinal conditions and glaucoma. At the same time, the technology continues to show potential for emerging clinical and research applications across all the ophthalmological subspecialties. To reflect these rapid advances, this new edition of Optical Coherence Tomography of Ocular Diseases features a complete and thorough revision of the existing text as well as the addition of cutting-edge content to bring this classic resource completely up to date.New content in the Fourth Edition includes:* OCT angiography* Swept-source OCT* OCT in multimodal imaging* Clinical utility of OCT in glaucoma prediction and progression detection * OCT for neuro-ophthalmology Optical Coherence Tomography of Ocular Diseases, Fourth Edition is the one and only book needed by practitioners who use OCT for clinical eye care.

Optical coherence tomography has become a part of clinical routine in everyday eye practice, allowing objective, quantitative structural assessment and driving clinical decision making in retinal diseases, glaucoma and cataract surgery. To guide the eyecare professionals who rely on this technology, Everyday OCT: A Handbook for Clinicians and Technicians, Second Edition is a user-friendly, practical reference that provides all of the information they need to know about current OCT technologies and their clinical utilities. Drs. Joel S. Schuman, Carmen A. Puliafito, James G. Fujimoto, and Jay S. Duker represent the cutting edge of OCT applications and, together with their expert contributing authors, they have created a clear and concise guide designed to provide clinicians and technicians with the knowledge and tips to best utilize OCT technology. This Second Edition is split into three parts: an operational guide with in-depth guidance and tips on the six major OCT devices from six different manufacturers, an interpretation guide featuring all the major pathologies OCT can visualize, and a technical guide containing detailed technical aspects of the SD-OCT and the future of OCT technologies.Everyday OCT, Second Edition explains how to: Set up and employ OCT technology Select and facilitate scans Ensure and assess the quality of scans Accurately interpret OCT images Everyday OCT: A Handbook for Clinicians and Technicians, Second Edition covers the diversity of new devices and applications in the field of OCT in a succinct and easy-to-read format, making it the ideal resource for clinicians and technicians to have by their side when performing or interpreting OCTs.

The most comprehensive text and definitive guide for nearly 30 years about optical coherence tomography (OCT) imaging in ophthalmology, Optical Coherence Tomography of Ocular Diseases, Fourth Edition covers a range of subjects, from principles and operation techniques to clinical interpretation and the latest innovations in OCT. Written by the pioneers of OCT technologies and the world-renowned OCT researchers Drs. Joel S. Schuman, James G. Fujimoto, Jay S. Duker, Hiroshi Ishikawa, and Gadi Wollstein, Optical Coherence Tomography of Ocular Diseases, Fourth Edition is an essential text for imaging technology.OCT now occupies a dominant role as a diagnostic tool for retinal conditions and glaucoma. At the same time, the technology continues to show potential for emerging clinical and research applications across all the ophthalmological subspecialties. To reflect these rapid advances, this new edition of Optical Coherence Tomography of Ocular Diseases features a complete and thorough revision of the existing text as well as the addition of cutting-edge content to bring this classic resource completely up to date.New content in the Fourth Edition includes:* OCT angiography* Swept-source OCT* OCT in multimodal imaging* Clinical utility of OCT in glaucoma prediction and progression detection * OCT for neuro-ophthalmology Optical Coherence Tomography of Ocular Diseases, Fourth Edition is the one and only book needed by practitioners who use OCT for clinical eye care.

The most comprehensive text and definitive guide for nearly 30 years about optical coherence tomography (OCT) imaging in ophthalmology, Optical Coherence Tomography of Ocular Diseases, Fourth Edition covers a range of subjects, from principles and operation techniques to clinical interpretation and the latest innovations in OCT. Written by the pioneers of OCT technologies and the world-renowned OCT researchers Drs. Joel S. Schuman, James G. Fujimoto, Jay S. Duker, Hiroshi Ishikawa, and Gadi Wollstein, Optical Coherence Tomography of Ocular Diseases, Fourth Edition is an essential text for imaging technology.OCT now occupies a dominant role as a diagnostic tool for retinal conditions and glaucoma. At the same time, the technology continues to show potential for emerging clinical and research applications across all the ophthalmological subspecialties. To reflect these rapid advances, this new edition of Optical Coherence Tomography of Ocular Diseases features a complete and thorough revision of the existing text as well as the addition of cutting-edge content to bring this classic resource completely up to date.New content in the Fourth Edition includes:• OCT angiography• Swept-source OCT• OCT in multimodal imaging• Clinical utility of OCT in glaucoma prediction and progression detection • OCT for neuro-ophthalmology Optical Coherence Tomography of Ocular Diseases, Fourth Edition is the one and only book needed by practitioners who use OCT for clinical eye care.

Optical coherence tomography (OCT) is the optical analog of ultrasound imaging and is a powerful imaging technique that enables non-invasive, in vivo, high resolution, cross-sectional imaging in biological tissue. Between 30 to 40 Million OCT imaging procedures are performed per year in ophthalmology. The overall market is estimated at more than 0.5 Billion USD.A new generation OCT technology was developed, dramatically increasing resolution and speed, achieving in vivo optical biopsy, i.e. the visualization of tissue architectural morphology in situ and in real time.  Functional extensions of OCT technology enable non-invasive, depth resolved functional assessment and imaging of tissue.The book introduces OCT technology and applications not only from an optical and technological viewpoint, but also from the biomedical and clinical perspective. This second edition is widely extended and covers significantly more topics then the first edition of this book. The chapters are written by leading international research groups, in a style comprehensible to a broad audience. It will be of interest not only to physicists, scientists and engineers, but also to biomedical and clinical researchers from different medical specialties.

Optical coherence tomography (OCT) is the optical analog of ultrasound imaging and is a powerful imaging technique that enables non-invasive, in vivo, high resolution, cross-sectional imaging in biological tissue. Between 30 to 40 Million OCT imaging procedures are performed per year in ophthalmology. The overall market is estimated at more than 0.5 Billion USD.A new generation OCT technology was developed, dramatically increasing resolution and speed, achieving in vivo optical biopsy, i.e. the visualization of tissue architectural morphology in situ and in real time.  Functional extensions of OCT technology enable non-invasive, depth resolved functional assessment and imaging of tissue.The book introduces OCT technology and applications not only from an optical and technological viewpoint, but also from the biomedical and clinical perspective. This second edition is widely extended and covers significantly more topics then the first edition of this book. The chapters are written by leading international research groups, in a style comprehensible to a broad audience. It will be of interest not only to physicists, scientists and engineers, but also to biomedical and clinical researchers from different medical specialties.

This volume contains papers presented at the Eleventh International Conference on Ultrafast Phenomena held at Garmisch-Partenkirchen, Germany, from July 12 to 17, 1998. The biannual Ultrafast Phenomena Conferences provide a forum for dis­ cussion of the latest advances in ultrafast optics and their applications in science and engineering. The Garmisch conference brought together a multidisciplinary group of 440 participants from 27 countries, including 127 students. The enthu­ siasm of this large number of Participants, the high quality of the papers they presented and the magnificent conference site resulted in a successful and pleasant conference. Progress was reported in the technology of generating ultrashort pulses, in­ cluding new techniques for improving laser-pulse duration, tunability over broad wavelength ranges, output power and peak intensity. Ultrafast spectroscopy con­ tinues to provide new insight into fundamental processes in physics, chemistry, biology, and engineering. In addition to analyzing ultrafast phenomena, control of ultrafast dynamics now represents an important topic. Ultrafast concepts and tech­ niques are being applied in imaging and microscopy, high speed optoelectronics, mat~rial diagnostics and processing, reflecting the maturing of the field. Acknowledgements. Many people contributed to the success of the conference.

This volume contains papers presented at the Eleventh International Conference on Ultrafast Phenomena held at Garmisch-Partenkirchen, Germany, from July 12 to 17, 1998. The biannual Ultrafast Phenomena Conferences provide a forum for dis­ cussion of the latest advances in ultrafast optics and their applications in science and engineering. The Garmisch conference brought together a multidisciplinary group of 440 participants from 27 countries, including 127 students. The enthu­ siasm of this large number of Participants, the high quality of the papers they presented and the magnificent conference site resulted in a successful and pleasant conference. Progress was reported in the technology of generating ultrashort pulses, in­ cluding new techniques for improving laser-pulse duration, tunability over broad wavelength ranges, output power and peak intensity. Ultrafast spectroscopy con­ tinues to provide new insight into fundamental processes in physics, chemistry, biology, and engineering. In addition to analyzing ultrafast phenomena, control of ultrafast dynamics now represents an important topic. Ultrafast concepts and tech­ niques are being applied in imaging and microscopy, high speed optoelectronics, mat~rial diagnostics and processing, reflecting the maturing of the field. Acknowledgements. Many people contributed to the success of the conference.

This volume contains papers presented at the Tenth International Conference on Ultrafast Phenomena held at Del Coronado, California, from May 28 to June 1, 1996. The biannual Ultrafast Phenomena Conferences provide a forum for the discussion of the latest advances in ultrafast optics and their applications in science and engineering. The Ultrafast Phenomena Conference maintains a broad international representation with 391 participants from 18 countries, including 94 students attending the conference. The multidisciplinary character of this meeting provides a cross-fertilization of ultrafast concepts and techniques among various scientific and engineering disciplines. The enthusiasm of the paticipants, the originality and quality of the papers that they presented, and the beautiful conference site combined to produce a very successful and enjoyable meeting. Progress was reported in the technology of generating ultrashort pulses, in­ cluding new techniques for improving laser-pulse duration, output power, wave­ length range, and compactness. Ultrafast spectroscopy continues to impact on and expand the knowledge base of fundamental processes in physics, chemistry, biol­ ogy and engineering. In addition ultrafast phenomena now extends to real-world applications in biology, high-speed communication, and material diagnostics. The Tenth Ultrafast Phenomena Conference was highlighted by a ''special event'' in which the developments of the previous conferences were reviewed in a panel discussion by G. Mourou, E. Ippen, A. Migus, A. Laubereau and R. Hochstrasser.

This volume contains papers presented at the Tenth International Conference on Ultrafast Phenomena held at Del Coronado, California, from May 28 to June 1, 1996. The biannual Ultrafast Phenomena Conferences provide a forum for the discussion of the latest advances in ultrafast optics and their applications in science and engineering. The Ultrafast Phenomena Conference maintains a broad international representation with 391 participants from 18 countries, including 94 students attending the conference. The multidisciplinary character of this meeting provides a cross-fertilization of ultrafast concepts and techniques among various scientific and engineering disciplines. The enthusiasm of the paticipants, the originality and quality of the papers that they presented, and the beautiful conference site combined to produce a very successful and enjoyable meeting. Progress was reported in the technology of generating ultrashort pulses, in­ cluding new techniques for improving laser-pulse duration, output power, wave­ length range, and compactness. Ultrafast spectroscopy continues to impact on and expand the knowledge base of fundamental processes in physics, chemistry, biol­ ogy and engineering. In addition ultrafast phenomena now extends to real-world applications in biology, high-speed communication, and material diagnostics. The Tenth Ultrafast Phenomena Conference was highlighted by a 'special event' in which the developments of the previous conferences were reviewed in a panel discussion by G. Mourou, E. Ippen, A. Migus, A. Laubereau and R. Hochstrasser.