Jingyu Hou – Författare

New Approaches of Protein Function Prediction from Protein Interaction Networks contains the critical aspects of PPI network based protein function prediction, including semantically assessing the reliability of PPI data, measuring the functional similarity between proteins, dynamically selecting prediction domains, predicting functions, and establishing corresponding prediction frameworks.

Functional annotation of proteins is vital to biological and clinical research and other applications due to the important roles proteins play in various biological processes. Although the functions of some proteins have been annotated via biological experiments, there are still many proteins whose functions are yet to be annotated due to the limitations of existing methods and the high cost of experiments. To overcome experimental limitations, this book helps users understand the computational approaches that have been rapidly developed for protein function prediction.

Provides innovative approaches and new developments targeting key issues in protein function prediction Presents heuristic ideas for further research in this challenging area

Due to the lack of a uniform schema for Web documents and the sheer amount and dynamics of Web data, both the effectiveness and the efficiency of information management and retrieval of Web data is often unsatisfactory when using conventional data management techniques.Web community, defined as a set of Web-based documents with its own logical structure, is a flexible and efficient approach to support information retrieval and to implement various applications. Zhang and his co-authors explain how to construct and analyse Web communities based on information like Web document contents, hyperlinks, or user access logs. Their approaches combine results from Web search algorithms, Web clustering methods, and Web usage mining. They also detail the necessary preliminaries needed to understand the algorithms presented, and they discuss several successful existing applications.Researchers and students in information retrieval and Web search find in this all the necessary basics and methods to create and understand Web communities. Professionals developing Web applications will additionally benefit from the samples presented for their own designs and implementations.