Joe Siple – författare

PATIENT CENTRIC BLOOD SAMPLING AND QUANTITATIVE ANALYSIS Authoritative resource providing a complete overview of patient centric blood sampling, as well as its benefits and challenges Patient Centric Blood Sampling and Quantitative Analysis focuses on the growing interest in alternative means to standard phlebotomy and analytical workflows for the collection and analysis of high-quality human biological samples for the quantitative determination of circulating drugs, their metabolites, and endogenous substances for clinical trials, routine healthcare and neonatal screening. The book clearly explains the benefits and constraints of having patients collect small volumes of blood in locations outside of a clinic (e.g at home), including: patient convenience; less invasive procedures; increased frequency of sampling; applicability to collecting samples from the young, elderly, and those in remote locations; greater frequency; and lower cost per sample. Readers will learn about approaches for successfully implementing patient centric sampling workflows in a number of scenarios, including the clinical setting and in the analytical laboratory. Edited by four recognized experts in this field, with additional specialists in the discipline enlisted to write the component chapters, enabling greater depth and detail to be added and further raising the scientific standing of the publication, Patient Centric Blood Sampling and Quantitative Analysis includes information on: Basics of patient centric blood sampling and techniques and approaches that are available and in development for the collection and analysis of the samplesScience behind patient centric blood sampling and its implications regarding human healthcare and wellbeingApplication areas of patient centric sampling, including drug development, clinical chemistry/pathology, therapeutic drug monitoring, and morePractical approaches to successful implementation for existing and developing purposes and workflows, and case studies to support implementation within an organizationGiving the reader a broad understanding of what patient centric sampling is and where it might be applied for existing and potential future areas, Patient Centric Blood Sampling and Quantitative Analysis is an essential resource on the subject for many different types of laboratories, areas of clinical research and healthcare, including those in pharmaceutical, clinical, and research functions.

The international bestselling novel about Murray McBride, a lonely 100-year-old man who’s outlived just about everyone he's ever loved. But when he meets a boy awaiting a heart transplant, Murray may learn something about finding meaning in life again . . . With all his family and friends gone except an estranged grandson, retired Major League ballplayer Murray McBride is looking for a reason to live. He finds it in Jason Cashman, a spirited 10-year-old boy with a terminal heart defect and a list of five things he wants to do before he dies. Murray is determined to help Jason fulfill his dreams. Together, they race against the limited time each has left, ticking off Jason’s wishes one by one. Along the way, Murray remembers what it’s like to be young, and Jason fights for the opportunity to grow old. But when tragedy strikes, their worlds are turned upside-down, and an unexpected gift is the only thing that can make Jason’s final wish come true. This heartwarming coming-of-old-age novel is perfect for fans of Fredrik Backman’s A Man Called Ove and Mike Gayle’s All the Lonely People.

In the second book in the international bestselling Mr. Murray McBride series, the path to finding future happiness might just be paved in the lessons of the past . . . Jason Cashman has reached the goal he spent the last twenty years seeking: raising a million dollars for charity. But instead of feeling content, he now feels empty. What comes next? When he meets Alexandra Lopez—a determined ten-year-old girl facing deportation and uncertainty—he is inspired by his old friend, Murray McBride, to help her fulfill five wishes before she must leave. Jason and Alexandra set out to check off as many of her wishes as possible, but when his transplanted heart begins to fail, he must choose between his obligations to the past and his hope for a future. This heartwarming coming-of-age novel is perfect for fans of Fredrik Backman’s A Man Called Ove and Robert Dugoni's The Extraordinary Life of Sam Hell.

The prequel to the Murray McBride series—by the author of the beloved USA Today international bestselling novel The Five Wishes of Mr. Murray McBride. The day before Murray McBride moves Jenny, his beloved wife of eighty years, into a memory care center, she convinces him to search for a case her grandfather buried long ago, said to contain “a treasure worth more than gold.” With the help of some new friends, Murray and Jenny retrace their steps from years before. Over the course of the day, Murray tenderly retells their love story—how they met, the challenges they faced and overcame, and their initial attempt at the quest. But the closer they get to the treasure, the more clearly Murray remembers why they abandoned the search the first time. With the exhilarating discovery at hand, Murray must decide whether to unearth the treasure, even if it means bringing up painful events from the past.This heartwarming novel is perfect for fans of Fredrik Backman’s A Man Called Ove and Lisa Wingate’s The Prayer Box.