Johannes Schmidt – författare

Today, the pressure on healthcare costs and resources is increasing, and especially for biopharmaceuticals that require parenteral administration, the inherent complex and invasive dosing procedure adds to the demand for efficient medical management. In light of the COVID-19 pandemic the value of drug delivery technologies in enabling a flexible care setting is broadly recognized. In such a setting, patients and their caregivers can choose the place of drug administration based on individual preferences and capabilities. This includes not only dosing in the clinic but also supervised at-home dosing and self-administration for eligible patients.

Formulation and Device Lifecycle Management of Biotherapeutics: A Guidance for Researchers and Drug Developers covers the various aspects of improving drug delivery of biological medicines with the ultimate goal to reduce dosing complexity associated with parenteral administration and, thus, enhance patient experience and drug administration-related healthcare capacity. The target audience are multidisciplinary researchers and drug developers in the pharmaceutical industry, biotech companies, and academia involved in formulation and device development. This includes pharmacology and medical experts in charge of generating nonclinical and clinical data to support approval of novel dosing regimens, and drug delivery scientists and engineers responsible for technical particulars of product optimizations. Moreover, professionals in market access and commercial functions are expected to benefit from the discussions about the impact of patient and healthcare provider needs and country-specific reimbursement models on realizing a truly convenient and cost and resource efficient drug delivery solution.

Summarizes formulation and device lifecycle management activities that enable customer-centric and sustainable drug delivery for biotherapeutics Describes the pharmacokinetic-based clinical development pathway for subcutaneous dosing alternatives to established intravenous formulations for monoclonal antibodies Details established clinical development pathways supporting the approval of automated subcutaneous injection devices and proposes novel concepts Discusses how to realize home- and self-administration of biotherapeutics in cancer care Highlights aspects of multidisciplinary formulation and device lifecycle management that can be leveraged across different disease areas and introduces a decision architecture on when and how drug developers should embark into related development activities

This edited collection is the first volume solely dedicated to research on Johann Gottfried Herder’s understanding of history, time, and temporalities.Although his ideas on time mark an important transition period that advanced the emergence of the modern world, scholars have rarely addressed Herder’s temporalities. In eight chapters, the volume examines and illuminates Herder’s conception of human freedom in connection with time; the importance of the concept of forces (Kräfte) for a dynamic ontology; human beings’ sensuous experience of inner and external temporality; Herder’s conception of Bildung, speculations on extra-terrestrial beings and on different perceptions of time; the mythological figure Nemesis and Herder’s view of the past and the future; the temporal dimension in Herder’s aesthetics; and Herder’s biblical studies in relationship to divine infinitude and human temporality. The volume concludes by outlining the influence of Herder’s understanding of time on following generations of thinkers.Forms of Temporality and Historical Time in the Work of Johann Gottfried Herder is ideal for scholars, graduates, and postgraduates interested in Herder’s metaphysics, epistemology, and philosophy of history, as well as any scholar concerned with eighteenth-century concepts of time and the emergence of the modern world at the beginning of the nineteenth century.

This edited collection is the first volume solely dedicated to research on Johann Gottfried Herder’s understanding of history, time, and temporalities.Although his ideas on time mark an important transition period that advanced the emergence of the modern world, scholars have rarely addressed Herder’s temporalities. In eight chapters, the volume examines and illuminates Herder’s conception of human freedom in connection with time; the importance of the concept of forces (Kräfte) for a dynamic ontology; human beings’ sensuous experience of inner and external temporality; Herder’s conception of Bildung, speculations on extra-terrestrial beings and on different perceptions of time; the mythological figure Nemesis and Herder’s view of the past and the future; the temporal dimension in Herder’s aesthetics; and Herder’s biblical studies in relationship to divine infinitude and human temporality. The volume concludes by outlining the influence of Herder’s understanding of time on following generations of thinkers.Forms of Temporality and Historical Time in the Work of Johann Gottfried Herder is ideal for scholars, graduates, and postgraduates interested in Herder’s metaphysics, epistemology, and philosophy of history, as well as any scholar concerned with eighteenth-century concepts of time and the emergence of the modern world at the beginning of the nineteenth century.

The German linguists Johannes Schmidt (1843-1901) and Hugo Schuchardt (1842-1927) sought to answer many questions relating to the development of Indo-European languages, which are all believed to be descended from a single common ancestor. Schmidt's Verwantschaftsverhältnisse was originally published in 1872 and Schuchardt's Über die Lautgesetze followed in 1885; here they are reissued together in one volume. Schmidt's work developed the 'wave model' of language change, to which Schuchardt also subscribed. According to this theory, linguistic innovations spread outwards concentrically like waves, which become progressively weaker as time elapses and the distance from their point of origin increases. Since later changes may not cover the same area, there may be no sharp boundaries between neighbouring languages or dialects. This theory stood in opposition to the tree model and the doctrine of sound laws propounded by the Neogrammarian school of linguists, which is roundly critiqued in Schuchardt's contribution.

Zum siebzehnten Mal bietet das Herder Jahrbuch eine Auswahl aktueller Forschung zu Johann Gottfried Herder. Die diesjährige Ausgabe versammelt Forschungsbeiträge zu Herders Gedanken zum "Buch der Natur", zum Journal meiner Reise und zu Herders Rezeption der Briten Locke, Hutcheson, Home und Burke sowie zu seiner Auseinandersetzung mit Swift (einschließlich der Transkription zweier unveröffentlichter Handschriften Herders). Auch in diesem Jahr präsentiert das Herder Jahrbuch die Fortführung der umfassenden Herder-Bibliographie von Primär- und Sekundärliteratur inklusive Register. Vier Rezensionen zu aktueller Herder-Literatur beschließen den Band. Das Herder Jahrbuch erscheint im Auftrag der Internationalen Herder-Gesellschaft im 2-Jahres-Rhythmus und bietet disziplinübergreifend Forschungsbeiträge in deutscher und englischer Sprache zu allen Aspekten von Herders Werk sowie zu dessen entstehungs- und wirkungsgeschichtlichen Kontexten.

Franz Lenk ( 898– 9 8) was one of the most well-known painters of Neue Sachlichkeit. The publication offers a current perspective on his oeuvre and artistic career. It poses questions not only about his artistic role models, but also about his worldview and how it is manifested in his painting. For instance, Lenk's ambivalent position during the years from 933 to 945 is analyzed and assessed within the context of the events of the time. Biographical and art-historical insights, including about the group " Die Sieben" (The Seven) and his participation in the exhibitions of the Carnegie Institute in Pittsburgh in the 93 s, are incorporated into the presentation. The exhibition and catalogue present numerous works from twenty-four private and public collections in Germany and Switzerland. Look inside

„Employer Branding“ wird betrieben, um sowohl von potenziellen als auch bereits beschäftigten Arbeitnehmern als attraktiver und glaubwürdiger Arbeitgeber wahrgenommen zu werden. Gerade im immer heftigeren „War for Talents“ können sich Organisationen dadurch einen bedeutenden Wettbewerbsvorteil verschaffen. Aber wie sieht es in Krisenzeiten aus?Dieses essential vermittelt anhand einer eigens durchgeführten qualitativen Studie, welche Auswirkungen die Corona-Pandemie auf ein krisengerechtes Employer Branding hat und wie die betroffenen Organisationen mit den bestehenden Herausforderungen professionell umgehen können.