John M. Stewart - Böcker

The third edition of this practical introduction to Python has been thoroughly updated, with all code migrated to Jupyter notebooks. The notebooks are available online with executable versions of all of the book's content (and more). The text starts with a detailed introduction to the basics of the Python language, without assuming any prior knowledge. Building upon each other, the most important Python packages for numerical math (NumPy), symbolic math (SymPy), and plotting (Matplotlib) are introduced, with brand new chapters covering numerical methods (SciPy) and data handling (Pandas). Further new material includes guidelines for writing efficient Python code and publishing code for other users. Simple and concise code examples, revised for compatibility with Python 3, guide the reader and support the learning process throughout the book. Readers from all of the quantitative sciences, whatever their background, will be able to quickly acquire the skills needed for using Python effectively.

Molecular diagnostics are increasingly used to help guide targeted therapy in solid organ tumors and hematologic malignancies. A large proportion of molecular testing is performed on limited-volume samples obtained via minimally invasive techniques, such as fine needle aspiration. Increasingly, cytopathologists play an essential role in this process, both in the triage of specimens during rapid on-site evaluation and in the evaluation of archival samples to determine suitability for ancillary testing. Therefore, it is imperative that practicing cytopathologists stay abreast of up-to-date diagnostic, prognostic, and predictive ancillary tests that can be used on limited cytologic material. This is a challenge since the landscape of known genomic alterations is constantly evolving and the subsequent set of testing options is ever expanding.The proposed text will provide a user-friendly quick-reference handbook to serve as a useful resource for practicing pathologistsand laboratory personnel dealing with, and interested in, this evolving field of molecular cytopathology. Essential components to be presented include: 1) pre-analytic factors that affect sample selection and evaluation; 2) specimen preparation to maximize confidence in results; 3) interpretation of results; 4) potential limitations; and 5) workflow algorithms.  In addition, specific disease specific molecular testing details will be outlined to provide the reader with resources for quick reference. All chapters will be written by experts in their fields and will include the most up-to-date scientific and clinical information.Molecular Diagnostics in Cytopathology will be of value to Cytopathologists, Cytotechnologists, Cytotechnology students, Cytopathology fellows, Surgical pathologists, Pathology residents and fellows, Molecular Pathologists, Molecular pathology fellows, Molecular technologists, as well as  Translational researchers with an interest in molecular cytopathology.