John Rossi - Böcker

Arguably the most influential political writer of the twentieth century, George Orwell remains a crucial voice for our times. Known world-wide for his two best-selling masterpieces Nineteen Eighty-Four, a gripping portrait of a dystopian future, and Animal Farm, a brilliant satire on the Russian Revolution, Orwell has been revered as an essayist, journalist and literary-political intellectual, and his works have exerted a powerful international impact on the post-World War Two era. This Introduction examines Orwell's life, work and legacy, addressing his towering achievement and his ongoing appeal. Combining important biographical detail with close analysis of his writings, the book considers the various genres in which Orwell wrote: the realistic novel, the essay, journalism and the anti-utopia. Ideally suited for readers approaching Orwell's work for the first time, the book concludes with an extended reflection on why George Orwell has enjoyed a literary afterlife unprecedented among modern authors in any language.

Arguably the most influential political writer of the twentieth century, George Orwell remains a crucial voice for our times. Known world-wide for his two best-selling masterpieces Nineteen Eighty-Four, a gripping portrait of a dystopian future, and Animal Farm, a brilliant satire on the Russian Revolution, Orwell has been revered as an essayist, journalist and literary-political intellectual, and his works have exerted a powerful international impact on the post-World War Two era. This Introduction examines Orwell's life, work and legacy, addressing his towering achievement and his ongoing appeal. Combining important biographical detail with close analysis of his writings, the book considers the various genres in which Orwell wrote: the realistic novel, the essay, journalism and the anti-utopia. Ideally suited for readers approaching Orwell's work for the first time, the book concludes with an extended reflection on why George Orwell has enjoyed a literary afterlife unprecedented among modern authors in any language.

This volume provides a collection of cutting-edge strategies in siRNA delivery that were developed and refined over the years with tried-and-true methods. Written by a team of internationally renowned authors, this book describes, in detail, a variety of successful siRNA delivery methods, including peptide-based nanoparticles, liposomes, exosomes, polymers, aptamers, and viral vehicles. Written in the highly successful Methods in Molecular Biology series format, each proven protocol includes brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Comprehensive and authoritative, SiRNA Delivery Methods: Methods and Protocols, will provide researchers, educators, clinicians, and biotechnology specialists with a broad understanding of the issues in siRNA delivery and how they can be overcome strategically.

This volume provides a collection of cutting-edge strategies in siRNA delivery that were developed and refined over the years with tried-and-true methods. Written by a team of internationally renowned authors, this book describes, in detail, a variety of successful siRNA delivery methods, including peptide-based nanoparticles, liposomes, exosomes, polymers, aptamers, and viral vehicles. Written in the highly successful Methods in Molecular Biology series format, each proven protocol includes brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Comprehensive and authoritative, SiRNA Delivery Methods: Methods and Protocols, will provide researchers, educators, clinicians, and biotechnology specialists with a broad understanding of the issues in siRNA delivery and how they can be overcome strategically.