John Saunders – författare
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83 produkter
83 produkter
449 kr
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Today's top selling drugs have been uncovered from two major sources: natural products and laboratory synthesis. Those synthesised directly by medicinal chemists usually have been the result of a protracted discovery programme using a natural product (e.g. a hormone or an enzyme substrate) or a screening lead as a starting point. Many of the major categories of human disease cardiovascular, gastrointestinal, central nervous system, inflammatory and infectious diseases are included. After a short introduction to the discovery and mechanism of action of each drug, the syntheses of the best selling drugs are reviewed. Where the information exists in the literature, the original research method to each drug is compared with more recent approaches which aim either at improving the route or at validating newer methodologies or reagents in the context of drug synthesis. Since, for many drugs, the marketed product was originally prepared as a racemic mixture, perhaps the most important comparison is between that route and alternatives which involve some element of asymmetric synthesis.
1 921 kr
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Originally published in 1986, this volume deals with both population growth in Latin America and the possible consequences of this growth for the security of the USA. The text analyses the demographic dimensions of the phenomenon and then considers the consequences for US security. It was the first time that the interrelations between national security and population growth were systematically analyzed. The book predicts the raid population growth would have serious economic, social and strategic implications for the USA and rightly predicts the adoption of draconian measures to stem the flow of illegal migrants. Although some aspects of the political landscape have changed since original publication the issue of migration to the USA from Latin America has lost none of its relevance.
Rural Electrification And Development
Social And Economic Impact In Costa Rica And Colombia
Inbunden, Engelska, 2019
2 126 kr
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Financing distribution of electric energy to rural areas in developing countries is a relatively recent activity. The United States Agency for International Development (AID) was the first to loan funds for this purpose. In 1963 it authorized $400, 000 to establish an electric cooperative in Nicaragua. Since then 15 loans have been made by AID for establishing or expanding electric service in nonurban areas of nine countries in Latin America. In this book, the emphasis has been placed on identifying benefits and, within the time and resources available, developing social indicators to place beside economic measurements. The authors have attempted to write this report in as nontechnical a style as possible and to provide a full exposition of all variables and methods employed so as to make it accessible to a general audience.
540 kr
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Originally published in 1986, this volume deals with both population growth in Latin America and the possible consequences of this growth for the security of the USA. The text analyses the demographic dimensions of the phenomenon and then considers the consequences for US security. It was the first time that the interrelations between national security and population growth were systematically analyzed. The book predicts the raid population growth would have serious economic, social and strategic implications for the USA and rightly predicts the adoption of draconian measures to stem the flow of illegal migrants. Although some aspects of the political landscape have changed since original publication the issue of migration to the USA from Latin America has lost none of its relevance.
Rural Electrification And Development
Social And Economic Impact In Costa Rica And Colombia
Häftad, Engelska, 2021
622 kr
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"This assessment of the consequences of rural electrification in developing areas, covers projects in two Latin American countries. In one of these electricity is supplied by a cooperative, in the other by a state-owned company. The authors examine a wide range of variables and find that only living standard and occupational status had a consistent positive association with electricity use. The cooperative had little, if any, significance for its members, aside from its function as an energy supplier. Household electricity consumption levels were low, rarely exceeding 100 kilowatts per month and largely limited to use for lighting and ironing. Farm consumption was minimal. The authors discuss energy costs at the household level and look at alternative energy sources, such as privately operated diesel generators, for businesses and industries. Consideration is given to the relationship between electricity and infrastructure development. The study is unique in that it focuses on both social and economic impacts of rural electrification and examines policy implications from both social-benefits and economic-benefits approaches."
188 kr
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A comprehensive, practical guide to playing chess from beginner to more advanced play with over 700 colour photographs and artworks.
How to Play and Win at Chess
Rules, skills and strategy, from beginner to expert, demonstrated in over 700 step-by-step illustrations
Inbunden, Engelska, 2022
167 kr
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This expertly presented book, updated in 2021/2 edition, tells you everything you need to know about chess. All the pieces and modern rules and terminology of chess are explained in an accessible and structured way, together with an evocative history of the game and its greatest players. The different strategies are explained along with how to manage the game as it progresses from opening through the middle game to the end game. Analysis and teaching commences at the most basic level, before moving on to intermediate and more advanced levels. Some of the historic chess masterpiece games are also explored in detail as inspiration for tactical play. Then the book offers ideas about where to play chess and who to play against. Options are outlined such as rapid play or blitz chess, which have timed finishes, and slow methods, such as correspondence chess, which involves long distance play. Understand the rules of the game, pieces and the chess board; includes the basics: how to practise, strategies for attack and defence and how to win the game; teaches chess opening strategies, middle games and good end game techniques at different levels of skill and experience; includes different ways of playing chess such as online chess, fast (rapid play and blitz) and slow games (correspondence chess); offers advice for becoming a more advanced player and playing in competition and even at a Chess Congress.
People's & Howitt's Journal
Of Literature, Art, And Popular Progress; Volume 3
Inbunden, Engelska, 2022
431 kr
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308 kr
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435 kr
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450 kr
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People's & Howitt's Journal
Of Literature, Art, And Popular Progress; Volume 2
Inbunden, Engelska, 2023
484 kr
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358 kr
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311 kr
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328 kr
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342 kr
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187 kr
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311 kr
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329 kr
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327 kr
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296 kr
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297 kr
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311 kr
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296 kr
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358 kr
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311 kr
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265 kr
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311 kr
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311 kr
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249 kr
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