Jon Marles-Wright - Böcker

This book follows on from Volume 83 in the SCBI series (“Macromolecular Protein Complexes”), and addresses several important topics (such as the Proteasome, Anaphase Promoting Complex, Ribosome and Apoptosome) that were not previously included, together with a number of additional exciting topics in this rapidly expanding field of study. Although the first SCBI Protein Complex book focused on soluble protein complexes, the second (Vol. 87)addressed Membrane Complexes, and the third (Vol. 88) put the spotlight on Viral Protein and Nucleoprotein Complexes, a number of membrane, virus and even fibrillar protein complexes have been be considered for inclusion in the present book.  A further book is also under preparation that follows the same pattern, in an attempt to provide a thorough coverage of the subject.Chapter 9 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

This book follows on from Volume 83 in the SCBI series (“Macromolecular Protein Complexes”), and addresses several important topics (such as the Proteasome, Anaphase Promoting Complex, Ribosome and Apoptosome) that were not previously included, together with a number of additional exciting topics in this rapidly expanding field of study.

This book covers important topics such as the dynamic structure and function of the 26S proteasome, the DNA replication machine: structure and dynamic function and the structural organization and protein–protein interactions in the human adenovirus capsid, to mention but a few.The 18 chapters included here, written by experts in their specific field, are at the forefront of scientific knowledge. The impressive integration of structural data from X-ray crystallography with that from cryo-electron microscopy is apparent throughout the book. In addition, functional aspects are also given a high priority. Chapter 1 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

This book covers important topics such as the dynamic structure and function of the 26S proteasome, the DNA replication machine: structure and dynamic function and the structural organization and protein–protein interactions in the human adenovirus capsid, to mention but a few.The 18 chapters included here, written by experts in their specific field, are at the forefront of scientific knowledge. The impressive integration of structural data from X-ray crystallography with that from cryo-electron microscopy is apparent throughout the book. In addition, functional aspects are also given a high priority. Chapter 1 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

The 17 interesting chapters included in this book have been organised into four sections: Soluble Protein Complexes, Membrane Protein Complexes, Fibrous Protein Complexes and Viral Protein Complexes.

This book covers the latest findings of a wide variety of viral, prokaryotic and eukaryotic macromolecular protein complexes and builds upon the solid macromolecular foundations established by previous volumes of the Subcellular Biochemistry series. Thus, an almost encyclopaedic coverage of the broad field of protein complex structure and function has been established. The 17 interesting chapters included in this book have been organised into four sections: Soluble Protein Complexes, Membrane Protein Complexes, Fibrous Protein Complexes and Viral Protein Complexes. Significant topics present here are: Fatty Acid Synthase, the Fork Protection Complex, Ribonucleotide Reductase, the Kinetochore, G proteins, the FtsEX Complex, the Kainate Receptor, the Photosystem I-antenna, the Mycobacterial Arabinofuranosyltransferases, the the Bacterial Flagellum, the Actomyosin Complex, Motile Cilia, SLS Collagen Polymorphic Structures, and the Reovirus Capsid and Polymerase. Up-dates/expansion of chapter topics present in earlier volumes are now included in chapters here, e.g., those on Ferritin-like proteins and the Multi-tRNA Synthetase. The book is richly illustrated throughout, the result of an impressive integration of structural data from X-ray crystallography and cryo-electron microscopy. The functional aspects of protein-protein interactions are also given a high priority.

This volume in the Subcellular Biochemistry (SCBI) series is a continuation of several previous volumes devoted to the structural and functional study of protein complexes. The expanding nature of this field of study, derived mainly from X-ray crystallography and electron cryomicroscopy, justifies the continuing expansion of coverage in an almost encyclopaedic manner within the SCBI series.Experienced and active researchers in the field shed light on the biology of protein complexes involved in important cellular functions from different perspectives, such as AcrAB-TolC, and CST. Other topics covered are: the Toxin-Antitoxin systems in cell survival, the role of the ATPases CueR and RUVBL1-RUVBL2 in the regulation of gene expression, complexes with multiple functions in the cell such as VCP/p97 or the Vault complex, FtsA and FtsZ in bacterial cell division, GATOR1 and GATOR2 in amino acid sensing, TRPA1 and the Serotonin Transporter in signaling, oligomeric structures in eukaryotic cells such as amyloids and invertases, among others.The book is richly illustrated, the result of an impressive integration of structural data from X-ray crystallography and cryo-electron microscopy. Functional aspects of protein-protein interactions are also featured prominently, providing a valuable contribution for researchers and scholars.Chapter 13 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

This volume in the Subcellular Biochemistry (SCBI) series is a continuation of several previous volumes devoted to the structural and functional study of protein complexes. The expanding nature of this field of study, derived mainly from X-ray crystallography and electron cryomicroscopy, justifies the continuing expansion of coverage in an almost encyclopaedic manner within the SCBI series.Experienced and active researchers in the field shed light on the biology of protein complexes involved in important cellular functions from different perspectives, such as AcrAB-TolC, and CST. Other topics covered are: the Toxin-Antitoxin systems in cell survival, the role of the ATPases CueR and RUVBL1-RUVBL2 in the regulation of gene expression, complexes with multiple functions in the cell such as VCP/p97 or the Vault complex, FtsA and FtsZ in bacterial cell division, GATOR1 and GATOR2 in amino acid sensing, TRPA1 and the Serotonin Transporter in signaling, oligomeric structures in eukaryotic cells such as amyloids and invertases, among others.The book is richly illustrated, the result of an impressive integration of structural data from X-ray crystallography and cryo-electron microscopy. Functional aspects of protein-protein interactions are also featured prominently, providing a valuable contribution for researchers and scholars.Chapter 13 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.