Jonathan Kessler – författare

This is a bold new text on image-guided cancer therapy bringing together the expertise and experience of interventional radiologists, surgeons, pulmonologists, gastroenterologists, radiation oncologists and diagnostic imagers in treating patients with cancer. This multidisciplinary guide provides detailed description of cutting-edge techniques that have transformed how tumors are diagnosed, targeted, palliated, and treated. Whether learning the basics of patient evaluation or refining procedural skills, this book is an essential reference for clinicians of all specialties pushing the frontier of personalized image-guided cancer treatment.The growth in this field has been greatly aided by technological improvements in ablative tools, imaging, and image-guided navigation. Practitioners of IO are a large workforce in most modern hospitals, responsible for a large number of patients daily. Understanding concepts underlying IO procedures, as well as devices and procedures available, is essential for all who participate in the care of the cancer patient.This book is a state-of-the-art overview of IO and is authored by the scientists and clinicians who have pioneered the field. Overall, it summarizes the history, current technology, common procedures, and future prospects in the field.  It includes procedures from many surgical and interventional radiologic disciplines because 1) it aims to be definitive, and 2) often procedures are performed partly in interventional radiology and partly in the surgical suite. This new edition includes 20 new chapters and delves deeper into specific treatment methods and practice guidelines.The book is separated into three main sections with multiple parts. In the first, the history and technical principles that underlie tumor ablation are presented. The second part discusses current imaging modalities used for guidance of these procedures and monitoring of their effectiveness. Included in this section are considerations of workflow, OR/IR architecture, and financial issues revolving around IO.  The book then moves on to organ-specific applications of IO, including 1) primary liver cancer, 2) metastatic tumors to the liver, 3) lung tumors, 4) renal tumors, 5) prostate tumors, 6) bone tumors, and 7) miscellaneous tumors. The currently available equipment and equipment anticipated in the near future, special populations, and illustrations of the most common procedures are also included.This book is intended to summarize the field for cancer interventionalists and surgeons at all levels. This field being highly collaborative, the authors of chapters in this book are from many disciplines, making this a definitive text on the theory and practice of IO relevant to all clinicians interested in cancer therapy.

Book 1 of the Basilosaurus Rising series Thirty million years ago, it ruled the seas.Now it hunts again.When an Antarctic ice shelf collapses, something long buried is unleashed.Basilosaurus, a sixty-foot carnivorous whale once thought extinct.At first, it is only a disturbance in the deep.Then ships vanish.Coastal waters turn deadly.Something vast begins moving toward the surface.As scientists race to understand what they have awakened, a terrifying truth emerges.This is not a rediscovery.It is the return of an apex predator the modern world is not prepared to face.The terror begins here.Continue the Basilosaurus saga in Basilosaurus Rising (Book 2).

Something ancient has awakened beneath the Pacific. Entombed for nearly two years in a man-made shell of liquid oxygen, the female Basilosaurus was never meant to wake again. But deep beneath the Kermadec Trench, rising hydrothermal vents crack her frozen prison—and heat does what pressure could not. She rises. As the ancient apex predator stirs from stasis, two living calves are born in the abyss. One cautious. One aggressive. And as they ascend into a modern ocean filled with ships, submarines, and fragile ecosystems, the balance of the deep begins to fracture. Marine paleontologist Dr. Laura Keating and cetacean expert Dr. Evan Holt are drawn back into a nightmare they believed had ended—while a U.S. Navy submarine encounters something no sonar profile can explain. What emerges from the darkness is not a relic, not a monster, but a living intelligence shaped by pressure, hunger, and instinct older than humanity itself. Basilosaurus Rising is a chilling sequel that blends hard science, deep-sea terror, and relentless suspense. Told from both human and inhuman perspectives, it explores what happens when an extinction-era predator reclaims a world that no longer belongs to it—and what modern civilization risks when the ocean's oldest ruler rises again. Perfect for fans of scientific horror, underwater thrillers, and prehistoric survival tales.

Some places are older than memory, and the land remembers every trespass. Three friends reunite for a quiet weekend at a remote manor deep in the Scottish Highlands. The plan is simple: escape the city, reconnect, and enjoy the solitude. But when one of them unknowingly disturbs a sacred grove hidden in the ancient forest beyond the estate, something awakens, something that has slept for centuries. From the moment they arrive, the woods around the manor feel watchful and wrong. Strange figures begin emerging from the forest, and the house itself seems disturbingly alive. Each of them is targeted by terrifying visions and invasive compulsions, twisted reflections of their deepest fears and unspoken flaws. Nature turns against them. Desperate and unraveling, they seek help from a reclusive local hermit who alone understands the ancient rites still binding the land. But the forces that have been disturbed are older than language, and they will not be appeased easily. THE WINDING is a chilling descent into folklore and psychological horror, a story about trespass, transformation, and the terrible price of waking what should have been left to rot.

The enemy was Rome. The real battle was the Alps. The Last Elephant is a harrowing and lyrical historical novel told through the eyes of Dios, a Greek military engineer swept into one of the most audacious campaigns in ancient history. When a Carthaginian army attempts the impossible by crossing the Alps with thousands of men, mules, and elephants, Dios finds himself pushed to the edge of endurance, sanity, and belief.As frostbite sets in, men mutiny, and the mountain itself turns hostile, Dios must navigate not only collapsing trails and failing maps, but also the dark interior terrain of trauma, superstition, and leadership under pressure. Each step forward comes at a staggering cost.Spare, immersive, and brutal in its beauty, The Last Elephant captures the vast indifference of nature and the fragile defiance of the human spirit.