Joo L. Ong - Böcker

Translating Biomaterials for Bone Graft: Bench-top to Clinical Applications brings together the current translational research in bone tissue engineering, from design to application – from materials, drugs and biologic delivery used for bone graft applications to pre-clinical and clinical considerations. The book also discusses the regulatory approval pathways, which involves consideration of the class of devices; whether they are similar to existing solutions, minimal manipulation of donor tissue or completely novel materials, drugs and biologics. These considerations drive the ability to successfully transition the latest generations of bone graft materials into the clinics. Chapters come from materials scientists, clinicians, researchers, and consultants and provide a holistic understanding of the field. As such, the book is a state-of-the-art reference to bone therapies and should appeal to clinicians, scientists, as well as students interested in the current research and/or practices in the field of bone regeneration and restoration.

Revised and updated throughout, the second edition of this succinct textbook provides the perfect introduction to biomaterials, linking the fundamental properties of metals, polymers, ceramics and natural biomaterials to the unique advantages and limitations surrounding their biomedical applications. New chapters on protein chemistry and interactions, immunology and tissue response, and biocompatibility round out student understanding. Clinical concerns such as sterilization, surface modification, cell-biomaterial interactions, drug delivery systems and tissue engineering are discussed, giving students insight into real-world challenges associated with biomaterials engineering. Key concepts are summarized alongside the text, allowing students to identify the most vital information. The final chapter discusses clinical applications, challenging students to consider future industrial possibilities. Concise enough to be taught in one semester, requiring only a basic understanding of biology, accompanied by over 180 end-of-chapter problems, and featuring color figures throughout, this accessible textbook continues to be ideal for students of engineering, materials science and medicine.