Juan C. Cruz – författare

Antimicrobial Peptides: A Roadmap for Accelerating Discovery and Development covers the most important efforts of scientists and engineers worldwide to accelerate the process of discovery, production, and eventual market penetration of more potent antimicrobial peptides. These efforts have been fueled by emerging technologies such as artificial intelligence and data science, molecular and CFD simulations, easy-to-use process simulation packages, microfluidics, 3D-printing, among many others. Such technologies can now be implemented and scaled up quickly and at relatively low cost in low-budget production facilities, critical to moving to sustainable and marketable products worldwide.Discovering novel antimicrobial peptides rationally and cost-effectively has emerged as one of the significant challenges of modern biotechnology. Thus far, this process has been tedious and costly, resulting in molecules with activities far below those needed to address the current challenge of microbial resistance to antibiotics that takes the lives of thousands of people around the world every year. Finally, the book also highlights how multidisciplinary teams have assembled to address the challenges of manufacturing, biological testing, and clinical trials to finally reach complete translation.

Covers computational tools (including emerging artificial intelligence algorithms) and microfluidic systems for discovery and high-throughput screening of AMPsDiscusses the application of bioprocess engineering scale-up approaches for AMPs' production and purification with the aid of process simulation tools and rapid prototypingHighlights user-centered design and formulation of products with AMPsDescribes the whole pipeline for AMPs production

Enzyme Kinetics: Fundamentals, Applications, and Reactor Design is a comprehensive guide that provides readers with a solid grounding in the principles of enzyme kinetics and bioreactor design while also illuminating their practical applications. The book takes a step-by-step approach, starting from basic concepts and gradually moving to advanced topics, to ensure that readers develop a strong understanding and are well-equipped to apply this knowledge in real-world scenarios. “Enzyme Kinetics: Fundamentals, Applications, and Reactor Design” covers crucial areas including safety regulations and future trends, making it an all-in-one resource for anyone interested in these fields. It also provides foundational information, explains methods and computational approaches, and presents case studies and applications. This book is designed to serve as a valuable resource for a broad range of readers, including undergraduate and graduate students studying biochemistry, biotechnology, and chemical engineering, as well as professionals and researchers looking to deepen their knowledge and stay at the forefront of their field. Enzyme Kinetics: Fundamentals, Applications, and Reactor Design offers an integrative and up-to-date perspective on enzyme kinetics and bioreactor design, with an emphasis on real-world applications, cutting-edge developments, and safety regulations.Offers a complete and up-to-date overview of enzyme kinetics and bioreactor design, moving from fundamental concepts to advanced topics and covering crucial areas like safety regulations and future trends, making it an all-in-one resource for anyone interested in these fieldsUniquely bridges the gap between theory and practice, with real-world applications and case studies integrated throughout the content, enabling readers to directly apply what they learn to their work or researchPresents information in a clear and accessible manner, with concepts broken down step-by-step to ensure they are easy to grasp, making this book an invaluable tool for both beginners and experienced professionals alike