Jun Shao - Böcker

Due to recent theoretical findings and advances in statistical computing, there has been a rapid development of techniques and applications in the area of missing data analysis. Statistical Methods for Handling Incomplete Data covers the most up-to-date statistical theories and computational methods for analyzing incomplete data.Features Uses the mean score equation as a building block for developing the theory for missing data analysis Provides comprehensive coverage of computational techniques for missing data analysis Presents a rigorous treatment of imputation techniques, including multiple imputation fractional imputation Explores the most recent advances of the propensity score method and estimation techniques for nonignorable missing data Describes a survey sampling application Updated with a new chapter on Data Integration Now includes a chapter on Advanced Topics, including kernel ridge regression imputation and neural network model imputation The book is primarily aimed at researchers and graduate students from statistics, and could be used as a reference by applied researchers with a good quantitative background. It includes many real data examples and simulated examples to help readers understand the methodologies.

Emphasizing the role of good statistical practices (GSP) in drug research and formulation, this book outlines important statistics applications for each stage of pharmaceutical development to ensure the valid design, analysis, and assessment of drug products under investigation and establish the safety and efficacy of pharmaceutical compounds. Coverage include statistical techniques for assay validation and evaluation of drug performance characteristics, testing population/individual bioequivalence and in vitro bioequivalence according to the most recent FDA guidelines, basic considerations for the design and analysis of therapeutic equivalence and noninferiority trials.

Praise for the Second Edition:"… this is a useful, comprehensive compendium of almost every possible sample size formula. The strong organization and carefully defined formulae will aid any researcher designing a study." -Biometrics"This impressive book contains formulae for computing sample size in a wide range of settings. One-sample studies and two-sample comparisons for quantitative, binary, and time-to-event outcomes are covered comprehensively, with separate sample size formulae for testing equality, non-inferiority, and equivalence. Many less familiar topics are also covered …" – Journal of the Royal Statistical SocietySample Size Calculations in Clinical Research, Third Edition presents statistical procedures for performing sample size calculations during various phases of clinical research and development. A comprehensive and unified presentation of statistical concepts and practical applications, this book includes a well-balanced summary of current and emerging clinical issues, regulatory requirements, and recently developed statistical methodologies for sample size calculation.Features: Compares the relative merits and disadvantages of statistical methods for sample size calculations Explains how the formulae and procedures for sample size calculations can be used in a variety of clinical research and development stages Presents real-world examples from several therapeutic areas, including cardiovascular medicine, the central nervous system, anti-infective medicine, oncology, and women’s health Provides sample size calculations for dose response studies, microarray studies, and Bayesian approaches This new edition is updated throughout, includes many new sections, and five new chapters on emerging topics: two stage seamless adaptive designs, cluster randomized trial design, zero-inflated Poisson distribution, clinical trials with extremely low incidence rates, and clinical trial simulation.

This book consists of solutions to four hundred exercises, over 95% of which are in the authors Mathematical Statistics. That textbook covers topics in statistical theory essential for graduate students preparing for work on a Ph. D. degree in statistics. On the other hand, this is a stand-alone book, since exercises and solutions are comprehensible independently of their source. Many solutions involve standard exercises that appear in other textbooks listed in the references. To help readers not using this book with Mathematical Statistics, lists of notation, terminology, and some probability distributions are given in the front of the book. Readers are assumed to have a good knowledge in advanced calculus. A course in real analysis or measure theory is highly recommended. If this book is used with a statistics textbook that does not include probability theory, then knowledge in measure-theoretic probability theory is required. The exercises are grouped into seven chapters with titles matching those in Mathematical Statistics. Jun Shao is Professor of Statistics at the University of Wisconsin, Madison.

The Jackknife and bootstrap are the most popular data-resampling methods used in statistical analysis. This book provides a systematic introduction to the theory of the jackknife, bootstrap and other resampling methods that have been developed in the last twenty years. It aims to provide a guide to using these methods which will enable applied statisticians to feel comfortable in applying them to data in their own research. The authors have included examples of applying these methods in various applications in both the independent and identically distributed (iid) case and in more complicated cases with non-iid data sets. Readers are assumed to have a reasonable knowledge of mathematical statistics and so this will be made suitable reading for graduate students, researchers and practitioners seeking a wide-ranging survey of this important area of statistical theory and application.

This graduate textbook covers topics in statistical theory essential for graduate students preparing for work on a Ph.D. degree in statistics. The first chapter provides a quick overview of concepts and results in measure-theoretic probability theory that are useful in statistics. The second chapter introduces some fundamental concepts in statistical decision theory and inference. Chapters 3-7 contain detailed studies on some important topics: unbiased estimation, parametric estimation, nonparametric estimation, hypothesis testing, and confidence sets. A large number of exercises in each chapter provide not only practice problems for students, but also many additional results. In addition to improving the presentation, the new edition makes Chapter 1 a self-contained chapter for probability theory with emphasis in statistics.Added topics include useful moment inequalities, more discussions of moment generating and characteristic functions, conditional independence, Markov chains, martingales, Edgeworth and Cornish-Fisher expansions, and proofs to many key theorems such as the dominated convergence theorem, monotone convergence theorem, uniqueness theorem, continuity theorem, law of large numbers, and central limit theorem. A new section in Chapter 5 introduces semiparametric models, and a number of new exercises were added to each chapter.

Emphasizing the role of good statistical practices (GSP) in drug research and formulation, this book outlines important statistics applications for each stage of pharmaceutical development to ensure the valid design, analysis, and assessment of drug products under investigation and establish the safety and efficacy of pharmaceutical compounds. Coverage include statistical techniques for assay validation and evaluation of drug performance characteristics, testing population/individual bioequivalence and in vitro bioequivalence according to the most recent FDA guidelines, basic considerations for the design and analysis of therapeutic equivalence and noninferiority trials.

Due to recent theoretical findings and advances in statistical computing, there has been a rapid development of techniques and applications in the area of missing data analysis. Statistical Methods for Handling Incomplete Data covers the most up-to-date statistical theories and computational methods for analyzing incomplete data.Features Uses the mean score equation as a building block for developing the theory for missing data analysis Provides comprehensive coverage of computational techniques for missing data analysis Presents a rigorous treatment of imputation techniques, including multiple imputation fractional imputation Explores the most recent advances of the propensity score method and estimation techniques for nonignorable missing data Describes a survey sampling application Updated with a new chapter on Data Integration Now includes a chapter on Advanced Topics, including kernel ridge regression imputation and neural network model imputation The book is primarily aimed at researchers and graduate students from statistics, and could be used as a reference by applied researchers with a good quantitative background. It includes many real data examples and simulated examples to help readers understand the methodologies.

Praise for the Second Edition:"… this is a useful, comprehensive compendium of almost every possible sample size formula. The strong organization and carefully defined formulae will aid any researcher designing a study." -Biometrics"This impressive book contains formulae for computing sample size in a wide range of settings. One-sample studies and two-sample comparisons for quantitative, binary, and time-to-event outcomes are covered comprehensively, with separate sample size formulae for testing equality, non-inferiority, and equivalence. Many less familiar topics are also covered …" – Journal of the Royal Statistical SocietySample Size Calculations in Clinical Research, Third Edition presents statistical procedures for performing sample size calculations during various phases of clinical research and development. A comprehensive and unified presentation of statistical concepts and practical applications, this book includes a well-balanced summary of current and emerging clinical issues, regulatory requirements, and recently developed statistical methodologies for sample size calculation.Features: Compares the relative merits and disadvantages of statistical methods for sample size calculations Explains how the formulae and procedures for sample size calculations can be used in a variety of clinical research and development stages Presents real-world examples from several therapeutic areas, including cardiovascular medicine, the central nervous system, anti-infective medicine, oncology, and women’s health Provides sample size calculations for dose response studies, microarray studies, and Bayesian approachesThis new edition is updated throughout, includes many new sections, and five new chapters on emerging topics: two stage seamless adaptive designs, cluster randomized trial design, zero-inflated Poisson distribution, clinical trials with extremely low incidence rates, and clinical trial simulation.

This graduate textbook covers topics in statistical theory essential for graduate students preparing for work on a Ph.D. degree in statistics. This new edition has been revised and updated and in this fourth printing, errors have been ironed out.

The resampling methods replace theoreti­ cal derivations required in applying traditional methods (such as substitu­ tion and linearization) in statistical analysis by repeatedly resampling the original data and making inferences from the resamples.

This book constitutes the proceedings of the satellite workshops held around the 20th International Conference on Applied Cryptography and Network Security, ACNS 2022, held in Rome, Italy, in June 2022. Due to the Corona pandemic the workshop was held as a virtual event. The 31 papers presented in this volume were carefully reviewed and selected from 52 submissions. They stem from the following workshops:– AIBlock: 4th ACNS Workshop on Application Intelligence and Blockchain Security– AIHWS: 3rd ACNS Workshop on Artificial Intelligence in Hardware Security– AIoTS: 4th ACNS Workshop on Artificial Intelligence and Industrial IoT Security– CIMSS: 2nd ACNS Workshop on Critical Infrastructure and Manufacturing System Security– Cloud S&P: 4th ACNS Workshop on Cloud Security and Privacy– SCI: 3rd ACNS Workshop on Secure Cryptographic Implementation– SecMT: 3rd ACNS Workshop on Security in Mobile Technologies– SiMLA: 4th ACNS Workshop on Security in Machine Learning and its Applications

This book constitutes the proceedings of the satellite workshops held around the 21st International Conference on Applied Cryptography and Network Security, ACNS 2023, held in Kyoto, Japan, in June 2023.The 34 full papers and 13 poster papers presented in this volume were carefully reviewed and selected from 76 submissions. They stem from the following workshops:·  1st ACNS Workshop on Automated Methods and Data-driven Techniques in Symmetric-key Cryptanalysis (ADSC 2023)·        5th ACNS Workshop on Application Intelligence and Blockchain Security (AIBlock 2023)·        4th ACNS Workshop on Artificial Intelligence in Hardware Security (AIHWS 2023)·        5th ACNS Workshop on Artificial Intelligence and Industrial IoT Security (AIoTS 2023)·        3rd ACNS Workshop on Critical Infrastructure and Manufacturing System Security (CIMSS 2023)·        5th ACNS Workshop on Cloud Security and Privacy (Cloud S&P 2023) ·        4th ACNS Workshop on Secure Cryptographic Implementation (SCI 2023)·        4th ACNS Workshop on Security in Mobile Technologies (SecMT 2023)·        5th ACNS Workshop on Security in Machine Learning and its Applications (SiMLA 2023)

This book constitutes the referred proceedings of the 7th International Conference on Attacks and Defenses for Internet-of-Things, ADIoT 2024, held as an hybrid event, in Hangzhou, China, during December 13–14, 2024.The 10 full papers were carefully reviewed and selected from 41 submissions.This conference focuses on both sides of IoT attacks and defenses, and seek original submissions that discuss either practical or theoretical solutions to identify IoT vulnerabilities and IoT security mechanisms.

This book constitutes the refereed proceedings of the 6th International Conference on EISA--Emerging Information Security and Applications, EISA 2025, held in Hangzhou, China, during December 12-13, 2025.The 10 full papers included in this book were carefully reviewed and selected from 38 submissions. This conference focuses the need for emerging techniques, theories and applications to protect information and practical security.