Kai Zhang – författare

Optogenetics represents a breakthrough technology capable of dynamically modulating molecular and cellular activity in live cells with high precision. This transformative technology made it possible to reversibly interrogate protein actions, cellular events, and animal behaviors with a simple flash of light. Manipulating the temporal and spatial profile of light enabled precise control of membrane potentials. This feature has inspired non-opsin-based optogenetics, which not only inherits the precise spatiotemporal resolution but also expands the targets into a diverse pool of biomolecules such as membrane receptors, ion channels, kinases, GTPases, and transcription factors. This book is unique because it emphasizes the design and applications of opsin-free optogenetic tools.

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Optogenetics represents a breakthrough technology capable of dynamically modulating molecular and cellular activity in live cells with high precision. This transformative technology made it possible to reversibly interrogate protein actions, cellular events, and animal behaviors with a simple flash of light. Manipulating the temporal and spatial profile of light enabled precise control of membrane potentials. This feature has inspired non-opsin-based optogenetics, which not only inherits the precise spatiotemporal resolution but also expands the targets into a diverse pool of biomolecules such as membrane receptors, ion channels, kinases, GTPases, and transcription factors. This book is unique because it emphasizes the design and applications of opsin-free optogenetic tools.

Key Features

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This book gathers the latest advances, innovations, and applications in the field of efficiency and performance engineering, as presented by leading international researchers and engineers at the TEPEN International Workshop on Fault Diagnostics and Prognostics (TEPEN-IWFDP), held in Qingdao, China, on May 8–11, 2024. Topics include machine and structural health monitoring, non-destructive testing and fault detection, diagnostic and prognostic for both operational and manufacturing processes, maintenance optimization and asset management, smart metamaterials and metastructures, artificial intelligent, and machine learning. The contributions, which are selected through a rigorous international peer-review process, share exciting ideas that spur novel research directions and foster new multidisciplinary collaborations.

The objective of Kai Zhang and his research is to assess the existing process monitoring and fault detection (PM-FD) methods. His aim is to provide suggestions and guidance for choosing appropriate PM-FD methods, because the performance assessment study for PM-FD methods has become an area of interest in both academics and industry. The author first compares basic FD statistics, and then assesses different PM-FD methods to monitor the key performance indicators of static processes, steady-state dynamic processes and general dynamic processes including transient states. He validates the theoretical developments using both benchmark and real industrial processes.

This book is a compilation of selected papers from the 16th Annual Meeting Conference on Porous Media (InterPore 2024). The work focuses on novel techniques for porous media materials, transport mechanisms in porous media, multiscale multiphysics, pore-scale modeling, and porous media mechanics. The contents make valuable contributions to academic researchers, engineers in the industry, and regulators of aviation authorities. As well, readers will encounter new ideas for problems in porous media science and engineering.

Practice has proven that conducting safety evaluations of reservoir dams has become a necessary measure to ensure the safety of water conservancy projects. This book introduces the development and achievements in the safety management of reservoir dams in China. Each chapter systematically sorts out and integrates evaluation measures related to different stages of the entire life cycle of reservoir dams, including planning, design, construction, operation and maintenance, repair and reinforcement, and decommissioning or removal, forming a complete dam safety evaluation management system.

This book emphasizes the importance of conducting on-site inspections for dam safety management. A differentiated safety evaluation method and disposal strategy have been proposed for different engineering scales, management levels, and risk levels, making the technical route of safety evaluation more reasonable and operable. The book is written as a reference book for professional engineers and is also suitable for post graduate courses.