In consultation with Consulting Editor, Dr. Charles Lightdale, Dr. Kenneth Chang has assembled top authors to provide a current update on the management of GERD. Clinical review articles provide updates on the these important topics: Mechanism and Pathophysiology of GERD; Personalized Approach in the work-up and management of GERD; Proton Pump Inhibitors; Radiofrequency Treatment for GERD; Trans-oral Incisionless Fundoplication (TIF); Innovations in Endoscopic Therapy for GERD; Laparoscopic Hernia Repair and Fundoplication, Failed Nissen; Laparoscopic Sphincter Augmentation (LINX); Refractory GERD and Functional Heartburn; and Extra-esophageal GERD and LPR. Readers will come away with the latest techniques and clinical applications to improve patient outcomes.

In this issue of Gastrointestinal Endoscopy Clinics of North America, guest editors Drs. Kenneth J. Chang and Jason B. Samarasena bring their considerable expertise to the topic of The Endoscopic Oncologist. The practice of gastrointestinal endoscopy intersects with oncology in many ways, much of it involving pre-cancerous conditions. But the endoscopist's role in diagnosing, staging, and treating cancer patients is expanding. This issue is devoted to the current and future role of the endoscopic oncologist, with topics such as endoscopic diagnosis of luminal gastrointestinal cancer and extra-luminal cancer; endoscopic resection for early cancer; and more.

Epidemiology of Lumbar Intervertebral Disc Degeneration, Structure and Biology of the Intervertebral Disc in Health and Disease, Nutrition of the Intervertebral Disc, The Endplate and Its Relevance with Intervertebral Disc Degeneration, Genetic Risk Factors in Intervertebral Disc Degeneration, Biomechanics of Intervertebral Disc Degeneration, Diagnostic Tools and Imaging Methods in Intervertebral Disc Degeneration, An Overview of the Management of Degenerative Disc Disease, Adjacent Level Disc Disease - Is it Really a Fusion Disease? Prosthetic Total Disc Replacement, Stem Cell Regeneration of the Intervertebral Disc, Gene Therapy for Intervertebral Disc Degeneration, Tissue Engineering for Intervertebral Disc Degeneration, Emerging Technologies for Molecular Therapy for Intervertebral Disc Degeneration, Intervertebral Disc Transplantation

As Executive Director of the H.H. Chao Comprehensive Digestive Disease Center, University of California, Irvine, Dr. Chang brings the wealth of hix experience and knowledge to the topic of interventional endoscopic ultrasound. His issue is divided into two sections, the first dealing with the best practices of interventional EUS.� Articles in this section address FNA of solid pancreatic tumors, pancreatic cysts, diagnosis of SMT's, lung cancer staging, pancreatic drainage, and celiac neurolysis. The second section addresses emerging technologies for intervention EUS. These articles discuss pancreatic cyst ablation, vascular access and therapy, anti-tumor agents, fiducial markers and brachytherapy, image enhancement, tumor ablation, and anastomosis.

The AFS Textbook of Foregut Disease serves as a comprehensive guide of information covering the fast-evolving field of foregut disease.  This textbook is designed as a partnership between gastroenterologists & gastrointestinal surgeons with an understanding that an essential component of moving forward in this field is through collaboration. This AFS textbook has been developed by the American Foregut Society, a premier society for foregut disease and all chapters are written by experts in the field. Readership is intended for gastroenterologists, GI and thoracic surgeons, gastroenterology and general surgery residents and fellows, medical students, and integrated health members that manage foregut disease. All chapters follow an organized format that contains many graphs, tables, intraoperative photographs, and illustrations of techniques. This textbook provides the most up-to-date scientific information and will be the definitive resource to guide both the diagnosis and management of foregut disease for years to come.

The AFS Textbook of Foregut Disease serves as a comprehensive guide of information covering the fast-evolving field of foregut disease.  This textbook is designed as a partnership between gastroenterologists & gastrointestinal surgeons with an understanding that an essential component of moving forward in this field is through collaboration. This AFS textbook has been developed by the American Foregut Society, a premier society for foregut disease and all chapters are written by experts in the field. Readership is intended for gastroenterologists, GI and thoracic surgeons, gastroenterology and general surgery residents and fellows, medical students, and integrated health members that manage foregut disease. All chapters follow an organized format that contains many graphs, tables, intraoperative photographs, and illustrations of techniques. This textbook provides the most up-to-date scientific information and will be the definitive resource to guide both the diagnosis and management of foregut disease for years to come.   

In consultation with Consulting Editor, Dr. Charles Lightdale, Dr. Kenneth Chang has assembled top authors to provide a current update on the management of GERD. Clinical review articles provide updates on the these important topics: Mechanism and Pathophysiology of GERD; Personalized Approach in the work-up and management of GERD; Proton Pump Inhibitors; Radiofrequency Treatment for GERD; Trans-oral Incisionless Fundoplication (TIF); Innovations in Endoscopic Therapy for GERD; Laparoscopic Hernia Repair and Fundoplication, Failed Nissen; Laparoscopic Sphincter Augmentation (LINX); Refractory GERD and Functional Heartburn; and Extra-esophageal GERD and LPR. Readers will come away with the latest techniques and clinical applications to improve patient outcomes.

In this issue of Gastrointestinal Endoscopy Clinics of North America, guest editors Drs. Kenneth J. Chang and Jason B. Samarasena bring their considerable expertise to the topic of The Endoscopic Oncologist. The practice of gastrointestinal endoscopy intersects with oncology in many ways, much of it involving pre-cancerous conditions. But the endoscopist's role in diagnosing, staging, and treating cancer patients is expanding. This issue is devoted to the current and future role of the endoscopic oncologist, with topics such as endoscopic diagnosis of luminal gastrointestinal cancer and extra-luminal cancer; endoscopic resection for early cancer; and more.

Epidemiology of Lumbar Intervertebral Disc Degeneration, Structure and Biology of the Intervertebral Disc in Health and Disease, Nutrition of the Intervertebral Disc, The Endplate and Its Relevance with Intervertebral Disc Degeneration, Genetic Risk Factors in Intervertebral Disc Degeneration, Biomechanics of Intervertebral Disc Degeneration, Diagnostic Tools and Imaging Methods in Intervertebral Disc Degeneration, An Overview of the Management of Degenerative Disc Disease, Adjacent Level Disc Disease - Is it Really a Fusion Disease? Prosthetic Total Disc Replacement, Stem Cell Regeneration of the Intervertebral Disc, Gene Therapy for Intervertebral Disc Degeneration, Tissue Engineering for Intervertebral Disc Degeneration, Emerging Technologies for Molecular Therapy for Intervertebral Disc Degeneration, Intervertebral Disc Transplantation

As Executive Director of the H.H. Chao Comprehensive Digestive Disease Center, University of California, Irvine, Dr. Chang brings the wealth of hix experience and knowledge to the topic of interventional endoscopic ultrasound. His issue is divided into two sections, the first dealing with the best practices of interventional EUS.� Articles in this section address FNA of solid pancreatic tumors, pancreatic cysts, diagnosis of SMT's, lung cancer staging, pancreatic drainage, and celiac neurolysis. The second section addresses emerging technologies for intervention EUS. These articles discuss pancreatic cyst ablation, vascular access and therapy, anti-tumor agents, fiducial markers and brachytherapy, image enhancement, tumor ablation, and anastomosis.

The AFS Textbook of Foregut Disease serves as a comprehensive guide of information covering the fast-evolving field of foregut disease.  This textbook is designed as a partnership between gastroenterologists & gastrointestinal surgeons with an understanding that an essential component of moving forward in this field is through collaboration. This AFS textbook has been developed by the American Foregut Society, a premier society for foregut disease and all chapters are written by experts in the field. Readership is intended for gastroenterologists, GI and thoracic surgeons, gastroenterology and general surgery residents and fellows, medical students, and integrated health members that manage foregut disease. All chapters follow an organized format that contains many graphs, tables, intraoperative photographs, and illustrations of techniques. This textbook provides the most up-to-date scientific information and will be the definitive resource to guide both the diagnosis and management of foregut disease for years to come.

The AFS Textbook of Foregut Disease serves as a comprehensive guide of information covering the fast-evolving field of foregut disease.  This textbook is designed as a partnership between gastroenterologists & gastrointestinal surgeons with an understanding that an essential component of moving forward in this field is through collaboration. This AFS textbook has been developed by the American Foregut Society, a premier society for foregut disease and all chapters are written by experts in the field. Readership is intended for gastroenterologists, GI and thoracic surgeons, gastroenterology and general surgery residents and fellows, medical students, and integrated health members that manage foregut disease. All chapters follow an organized format that contains many graphs, tables, intraoperative photographs, and illustrations of techniques. This textbook provides the most up-to-date scientific information and will be the definitive resource to guide both the diagnosis and management of foregut disease for years to come.