Khawaja H. Haider – författare

In this volume, the contributing authors from top labs involved in stem cell theranostics share the latest advances in the field of stem cell research. The book covers many aspects of stem cell-based therapy and the progress made toward stem cell therapy for liver, ocular, and cardiovascular diseases as well as cancer. This volume serves as a continuation of Prof. Khawaja Husnain Haider’s previously edited books pertaining to stem cells-based therapnostics.

 In diesem Band berichten die Autoren aus führenden Labors, die sich mit Stammzelltheranostik beschäftigen, über die neuesten Fortschritte auf dem Gebiet der Stammzellforschung. Das Buch befasst sich mit vielen Aspekten der stammzellbasierten Therapie und den Fortschritten in der Stammzelltherapie bei Leber-, Augen- und Herz-Kreislauf-Erkrankungen sowie bei Krebs. Dieser Band ist eine Fortsetzung der von Prof. Khawaja Husnain Haider bereits herausgegebenen Bücher zur stammzellbasierten Therapienostik.

Es ist ein ideales Buch für Forscher, die sich mit der Entwicklung von Arzneimitteln sowie mit regenerativer Medizin und stammzellbasierter Therapie beschäftigen. Die sekundäre Zielgruppe umfasst Medizinstudenten, Ärzte, Zellpharmakologen, die Arzneimittelindustrie und Forscher, die Stammzellen als Ex-vivo-Krankheitsmodelle für die Arzneimittelentwicklung verwenden. 

The book covers multifarious aspects of stem cell-based therapy for cardiovascular diseases. In addition to stem cells from different sources for cell-based therapy, it covers stem cell organoids and stem cell-derived exosomes in regenerative medicine. The book also encompasses advances in state-of-the-art infrastructure to improve the maturation aspects of pluripotent stem cells-derived cardiomyocytes using a novel scaffold-based cell culture system for cell delivery in experimental animal models and clinical settings. Besides the use of mesenchymal stem cells, the book includes chapters on the use of cardiac progenitor cells (CPCs), microtissue implantation, use of PSCs for valvulopathies, application of de-cellularized organ arrays as natural scaffolds for cardiac tissue engineering, use of epicardial stem cells, and skeletal myoblasts in cell-based therapy for myocardial regeneration. Besides the cell-based therapy approach, the book also reviews the stem cell-derived exosomes,their characteristics, and engineering strategies to enhance their therapeutic potential via targeting and drug loading and use in disease models. Additionally, the book also discusses the latest research on injectable hydrogels for cardiovascular regeneration and how hydrogel-based delivery protects the cells and their retention post-engraftment in the heart, a problem, which significantly reduces the efficacy of cell-based therapy.