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2 produkter
1 458 kr
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Peptides serve as effective drugs in the clinic today. However the inherent drawbacks of peptide structures can limit their efficacy as drugs. To overcome this researchers are developing new methods to create ‘tailor-made’ peptides and proteins with improved pharmacological properties. Design of Peptides and Proteins provides an overview of the experimental and computational methods for peptide and protein design, with an emphasis on specific applications for therapeutics and biomedical research. Topics covered include: Computer modeling of peptides and proteinsPeptidomimeticsDesign and synthesis of cyclic peptidesCarbohydrates in peptide and protein designDe novo design of peptides and proteinsMedical development applicationsAn extended case study – the design of insulin variantsDesign of Peptides and Proteins presents the state-of-the-art of this exciting approach for therapeutics, with contributions from international experts. It is an essential resource for academic and industrial scientists in the fields of peptide and protein drug design, biomedicine, biochemistry, biophysics, molecular modelling, synthetic organic chemistry and medicinal/pharmaceutical chemistry.
1 908 kr
Skickas inom 10-15 vardagar
Education, Democracy and Discourse presents a commentary on democracy in education, and the macro- and micro-political discourses which permit and prohibit this. The key themes explored are: The struggle for democracy in schools and society, the relationships between the processes of schooling and the preparation of the workforce in advanced capitalist societies, the radical transformations of schooling as part of state modernization projects of the neo-conservatives, the neo-liberals and the third way, the creeping destruction of the professional status and culture of public sector workers such as teachers, nurses and social workers. Education, Democracy and Discourse addresses and develops crucial theories in sociology and in the sociology of education and will be of key interest to sociologists and Education Studies students.