Lauren E. Abrey - Böcker

Leptomeningeal Metastases is intended to provide the reader with an overview of the state-of-the-art therapy for the cancer patient with leptomeningeal cancer with additional information on epidemiology, symptom management, new clinical trials, and current basic research in animal models for experimental therapies.

Brain metastases are the most dreaded complication of systemic cancer, affecting approximately 170,000 people a year, a far greater incidence than primary brain tumors. Advances in modern chemotherapy have led to an improved control of system cancers, often with agents that poorly penetrate the central nervous system, resulting in an increasing incidence of brain metastases. Traditional chemotherapy has had little impact on brain metastases. The main therapeutic option is radiation therapy, and in a small number of patients - surgery. However, refinements in all of these treatments offer some positive outcomes and an increased ability to stratify patients based on certain criteria.This book will bring current information on the presentation and management of patients with brain metastases, providing available data, giving guidelines that can be applied in day to day practice, updated information for neuro-surgeons, radiation oncologists, medical oncologists, and neuro-oncologists, as well as an overview for physicians in training.

Leptomeningeal Metastases is intended to provide the reader with an overview of the state-of-the-art therapy for the cancer patient with leptomeningeal cancer with additional information on epidemiology, symptom management, new clinical trials, and current basic research in animal models for experimental therapies.