Lawrence Berliner – författare
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36 produkter
36 produkter
Del 24 - Biological Magnetic Resonance
Biomedical EPR - Part B: Methodology, Instrumentation, and Dynamics
Inbunden, Engelska, 2004
2 236 kr
Skickas inom 10-15 vardagar
Biomedical EPR – Part B focuses on applications of EPR techniques and instrumentation, with applications to dynamics. The book celebrates the 70th birthday of Prof. James S. Hyde, Medical College of Wisconsin, and his contributions to this field. Chapters are written to provide introductory material for new-comers to the field that lead into up-to-date reviews that provide perspective on the wide range of questions that can be addressed by EPR. Key Features:EPR Techniques including Saturation Recovery, ENDOR, ELDOR, and Saturation Transfer Instrumentation Innovations including Loop Gap Resonators, Rapid Mixing, and Time Locked Sub-Sampling Motion in Biological Membranes Applications to Structure Determination in Proteins Discussion of Trends in EPR Technology and Prognosis for the Future
E-bok
PDF, Engelska, 20062 822 kr
Läs direkt efter köp
Biomedical EPR – Part B focuses on applications of EPR techniques and instrumentation, with applications to dynamics. The book celebrates the 70th birthday of Prof. James S. Hyde, Medical College of Wisconsin, and his contributions to this field. Chapters are written to provide introductory material for new-comers to the field that lead into up-to-date reviews that provide perspective on the wide range of questions that can be addressed by EPR.
Key Features:EPR Techniques including Saturation Recovery, ENDOR, ELDOR, and Saturation Transfer
Instrumentation Innovations including Loop Gap Resonators, Rapid Mixing, and Time Locked Sub-Sampling
Motion in Biological Membranes
Applications to Structure Determination in Proteins
Discussion of Trends in EPR Technology and Prognosis for the Future
Inbunden, Engelska, 2007
2 176 kr
Skickas inom 10-15 vardagar
Spectroscopic methods are not only important as an analytical tool, they also provide information about fundamental physical and chemical properties of molecules, the molecular and electronic structure, and the dynamic behaviour of molecules. Starting from a comprehensive quantum mechanical description, ESR Spectroscopy in Membrane Biophysics introduces the optical (IR, Raman, UV/Vis, CD, fluorescence and laser spectroscopy) and magnetic resonance (1D and 2D-NMR, ESR) techniques. ESR Spectroscopy in Membrane Biophysics is a timely review of the increasing interest in using spin-label ESR as an alternative structural technique for NMR or X-ray diffraction. It is aimed at training an audience to learn ESR spectroscopy to determine membrane protein structures, conformational dynamics and protein-lipid interaction.
Del 25 - Biological Magnetic Resonance
Computational and Instrumental Methods in EPR
Inbunden, Engelska, 2006
1 091 kr
Skickas inom 10-15 vardagar
Electron magnetic resonance in the time domain has been greatly facilitated by the introduction of novel resonance structures and better computational tools, such as the increasingly widespread use of density-matrix formalism. This second v- ume in our series, devoted both to instrumentation and computation, addresses - plications and advances in the analysis of spin relaxation time measurements. Chapters 1 deals with the important problem of measuring spin relaxation times over a broad temporal range. The author, Dr. Sushil Misra, has worked on a wide variety of solutions to problems in this area, with respect to both experimental and theoretical aspects, and Chapter 1 summarizes much of his recent work, which was enhanced by a fruitful collaboration with the late Professor Jacques Pescia. Chapter 2 presents solutions to the problem of measuring short spin relaxation times. Again, in collaboration and tribute to the late Jacques Pescia's laboratory, part of the chapter represents a translation of the amplitude modulation technique section from a doctoral thesis by Robert Lopez in 1993 to The Paul Sabatier U- versity. Experimental data that appeared in the original thesis are placed at the end of subsections that correspond to the described technique. Chapter 3 takes up the problem of multi-frequency ENDOR and ESEEM, and illustrates how small stepwise increments of spectrometer operating parameters can enable one to better determine spin-Hamiltonian parameters via a graphical analysis.
Inbunden, Engelska, 2006
2 241 kr
Skickas inom 10-15 vardagar
From the early examples of what was to be called MRI, extending the te- nique to higher fields than those of less than 0. 1 T used in the first large-volume instruments was a goal, but the way there was unclear. The practical success of large superconducting magnets was a surprise, and the astonishment continued as they developed fields from 0. 3 T to 0. 6 T to 1. 5 T, and even more, up to the now common 3T systems, and a few 4T machines, and now to about 100 times the fields used in the first medium- and large-bore devices. In the early machines, low radiofrequencies of 4 MHz or so meant that RF coil designs were simple (even inexperienced undergraduates could design and build such circuits with little knowledge of more than DC electrical circuits), and the forces on gradient coils were small. The effects of magnetic susceptibility in- mogeneity in and around the object being imaged were negligible, and RF penet- tion depths were not a problem for human-scale samples. Everything began to change as higher fields and higher frequencies came into use, and the earlier idyllic simplicities began to seem quaint. The trend continued, however, driven by the increased signal-to-noise ratios and the resultant higher resolutions and speed available, and sophisticated engineering became more and more essential, not only for magnets but for gradient systems and radiofrequency transmitters and receivers, but also for better software for modeling and correcting distortions.
E-bok
PDF, Engelska, 20071 367 kr
Läs direkt efter köp
Electron magnetic resonance in the time domain has been greatly facilitated by the introduction of novel resonance structures and better computational tools, such as the increasingly widespread use of density-matrix formalism. This second v- ume in our series, devoted both to instrumentation and computation, addresses - plications and advances in the analysis of spin relaxation time measurements. Chapters 1 deals with the important problem of measuring spin relaxation times over a broad temporal range. The author, Dr. Sushil Misra, has worked on a wide variety of solutions to problems in this area, with respect to both experimental and theoretical aspects, and Chapter 1 summarizes much of his recent work, which was enhanced by a fruitful collaboration with the late Professor Jacques Pescia. Chapter 2 presents solutions to the problem of measuring short spin relaxation times. Again, in collaboration and tribute to the late Jacques Pescia''s laboratory, part of the chapter represents a translation of the amplitude modulation technique section from a doctoral thesis by Robert Lopez in 1993 to The Paul Sabatier U- versity. Experimental data that appeared in the original thesis are placed at the end of subsections that correspond to the described technique. Chapter 3 takes up the problem of multi-frequency ENDOR and ESEEM, and illustrates how small stepwise increments of spectrometer operating parameters can enable one to better determine spin-Hamiltonian parameters via a graphical analysis.
E-bok
PDF, Engelska, 20072 822 kr
Läs direkt efter köp
Spectroscopic methods are not only important as an analytical tool, they also provide information about fundamental physical and chemical properties of molecules, the molecular and electronic structure, and the dynamic behaviour of molecules. Starting from a comprehensive quantum mechanical description, ESR Spectroscopy in Membrane Biophysics introduces the optical (IR, Raman, UV/Vis, CD, fluorescence and laser spectroscopy) and magnetic resonance (1D and 2D-NMR, ESR) techniques.
ESR Spectroscopy in Membrane Biophysics is a timely review of the increasing interest in using spin-label ESR as an alternative structural technique for NMR or X-ray diffraction. It is aimed at training an audience to learn ESR spectroscopy to determine membrane protein structures, conformational dynamics and protein-lipid interaction.
E-bok
PDF, Engelska, 20072 822 kr
Läs direkt efter köp
From the early examples of what was to be called MRI, extending the te- nique to higher fields than those of less than 0. 1 T used in the first large-volume instruments was a goal, but the way there was unclear. The practical success of large superconducting magnets was a surprise, and the astonishment continued as they developed fields from 0. 3 T to 0. 6 T to 1. 5 T, and even more, up to the now common 3T systems, and a few 4T machines, and now to about 100 times the fields used in the first medium- and large-bore devices. In the early machines, low radiofrequencies of 4 MHz or so meant that RF coil designs were simple (even inexperienced undergraduates could design and build such circuits with little knowledge of more than DC electrical circuits), and the forces on gradient coils were small. The effects of magnetic susceptibility in- mogeneity in and around the object being imaged were negligible, and RF penet- tion depths were not a problem for human-scale samples. Everything began to change as higher fields and higher frequencies came into use, and the earlier idyllic simplicities began to seem quaint. The trend continued, however, driven by the increased signal-to-noise ratios and the resultant higher resolutions and speed available, and sophisticated engineering became more and more essential, not only for magnets but for gradient systems and radiofrequency transmitters and receivers, but also for better software for modeling and correcting distortions.
Inbunden, Engelska, 2009
2 241 kr
Skickas inom 10-15 vardagar
Metalloproteins comprise approximately 30% of all known proteins, and are involved in a variety of biologically important processes, including oxygen transport, biosynthesis, electron transfer, biodegradation, drug metabolism, proteolysis, and hydrolysis of amides and esters, environmental sulfur and nitrogen cycles, and disease mechanisms. EPR spectroscopy has an important role in not only the geometric structural characterization of the redox cofactors in metalloproteins but also their electronic structure, as this is crucial for their reactivity. The advent of x-ray crystallographic snapshots of the active site redox cofactors in metalloenzymes in conjunction with high-resolution EPR spectroscopy has provided detailed structural insights into their catalytic mechanisms.This volume was conceived in 2005 at the Rocky Mountain Conference on Analytical Chemistry (EPR Symposium) to highlight the importance of high-resolution EPR spectroscopy to the structural (geometric and electronic) characterization of redox active cofactors in metalloproteins. We have been fortunate to have enlisted internationally recognized experts in this joint venture to provide the scientific community with an overview of high-resolution EPR and its application to metals in biology. This volume, High-Resolution EPR: Applications to Metalloenzymes and Metals in Medicine, covers high-resolution EPR methods, iron proteins, nickel and copper enzymes, and metals in medicine. An eloquent synopsis of each chapter is provided by John Pilbrow in the Introduction. A second volume, Metals in Biology: Applications of High-Resolution EPR to Metalloenzymes, will appear later this year covering the complement of other metalloproteins.One of the pioneers in the development of pulsed EPR and its application to metalloproteins was Arthur Schweiger, whose contribution we include in this volume. Unfortunately, he passed away suddenly during the preparation of this volume. The editors andcoauthors are extremely honored to dedicate this volume to the memory of Arthur Schweiger in recognition of his technical advances and insights into pulsed EPR and its application to metalloproteins. Arthur was extremely humble and treated everyone with equal respect. He was a gifted educator with an ability to explain complex phenomena in terms of simple intuitive pictures, had a delightful personality, and continues to be sadly missed by the community.It is an honor for the editors to facilitate the dissemination of these excellent contributions to the scientific community. Suggestions for future volumes are always appreciated.
E-bok
PDF, Engelska, 20092 822 kr
Läs direkt efter köp
Metalloproteins comprise approximately 30% of all known proteins, and are involved in a variety of biologically important processes, including oxygen transport, biosynthesis, electron transfer, biodegradation, drug metabolism, proteolysis, and hydrolysis of amides and esters, environmental sulfur and nitrogen cycles, and disease mechanisms. EPR spectroscopy has an important role in not only the geometric structural characterization of the redox cofactors in metalloproteins but also their electronic structure, as this is crucial for their reactivity. The advent of x-ray crystallographic snapshots of the active site redox cofactors in metalloenzymes in conjunction with high-resolution EPR spectroscopy has provided detailed structural insights into their catalytic mechanisms.
This volume was conceived in 2005 at the Rocky Mountain Conference on Analytical Chemistry (EPR Symposium) to highlight the importance of high-resolution EPR spectroscopy to the structural (geometric and electronic) characterization of redox active cofactors in metalloproteins. We have been fortunate to have enlisted internationally recognized experts in this joint venture to provide the scientific community with an overview of high-resolution EPR and its application to metals in biology. This volume, High-Resolution EPR: Applications to Metalloenzymes and Metals in Medicine, covers high-resolution EPR methods, iron proteins, nickel and copper enzymes, and metals in medicine. An eloquent synopsis of each chapter is provided by John Pilbrow in the Introduction. A second volume, Metals in Biology: Applications of High-Resolution EPR to Metalloenzymes, will appear later this year covering the complement of other metalloproteins.
One of the pioneers in the development of pulsed EPR and its application to metalloproteins was Arthur Schweiger, whose contribution we include in this volume. Unfortunately, he passed away suddenly during the preparation of this volume. The editors andcoauthors are extremely honored to dedicate this volume to the memory of Arthur Schweiger in recognition of his technical advances and insights into pulsed EPR and its application to metalloproteins. Arthur was extremely humble and treated everyone with equal respect. He was a gifted educator with an ability to explain complex phenomena in terms of simple intuitive pictures, had a delightful personality, and continues to be sadly missed by the community.
It is an honor for the editors to facilitate the dissemination of these excellent contributions to the scientific community. Suggestions for future volumes are always appreciated.
E-bok
PDF, Engelska, 20103 137 kr
Läs direkt efter köp
Metal ions in biology is an ever expanding area in science and medicine involving metal ions in proteins and enzymes, their biosynthesis, catalysis, electron transfer, metal ion trafficking, gene regulation and disease. While X-ray crystallography has provided snapshots of the geometric structures of the active site redox cofactors in these proteins, the application of high resolution EPR spectroscopy in conjunction with quantum chemistry calculations has enabled, in many cases, a detailed understanding of a metalloenzymes mechanism through investigations of the geometric and electronic structure of the resting, enzyme-substrate intermediates and product complexes.
This volume, Part II of a two-volume set demonstrates the application of high resolution EPR spectroscopy in determining the geometric and electronic structure of active site metal ion centers in iron sulfur cluster containing metalloproteins, mononuclear molybdenum metalloenzymes, manganese-containing enzymes and novel metalloproteins.
Häftad, Engelska, 2010
2 241 kr
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Biomedical EPR -- Part B focuses on applications of EPR techniques and instrumentation, with applications to dynamics. The book celebrates the 70th birthday of Prof. James S. Hyde, Medical College of Wisconsin, and his contributions to this field. Chapters are written to provide introductory material for new-comers to the field that lead into up-to-date reviews that provide perspective on the wide range of questions that can be addressed by EPR. Key Features:EPR Techniques including Saturation Recovery, ENDOR, ELDOR, and Saturation Transfer Instrumentation Innovations including Loop Gap Resonators, Rapid Mixing, and Time Locked Sub-Sampling Motion in Biological Membranes Applications to Structure Determination in Proteins Discussion of Trends in EPR Technology and Prognosis for the Future
Del 25 - Biological Magnetic Resonance
Computational and Instrumental Methods in EPR
Häftad, Engelska, 2010
1 091 kr
Skickas inom 10-15 vardagar
Electron magnetic resonance in the time domain has been greatly facilitated by the introduction of novel resonance structures and better computational tools, such as the increasingly widespread use of density-matrix formalism. This second v- ume in our series, devoted both to instrumentation and computation, addresses - plications and advances in the analysis of spin relaxation time measurements. Chapters 1 deals with the important problem of measuring spin relaxation times over a broad temporal range. The author, Dr. Sushil Misra, has worked on a wide variety of solutions to problems in this area, with respect to both experimental and theoretical aspects, and Chapter 1 summarizes much of his recent work, which was enhanced by a fruitful collaboration with the late Professor Jacques Pescia. Chapter 2 presents solutions to the problem of measuring short spin relaxation times. Again, in collaboration and tribute to the late Jacques Pescia's laboratory, part of the chapter represents a translation of the amplitude modulation technique section from a doctoral thesis by Robert Lopez in 1993 to The Paul Sabatier U- versity. Experimental data that appeared in the original thesis are placed at the end of subsections that correspond to the described technique. Chapter 3 takes up the problem of multi-frequency ENDOR and ESEEM, and illustrates how small stepwise increments of spectrometer operating parameters can enable one to better determine spin-Hamiltonian parameters via a graphical analysis.
Häftad, Engelska, 2011
549 kr
Skickas inom 10-15 vardagar
We are again proud to present an excellent volume of contemporary topics in NMR and EPR to the biological community. The philosophy behind the volume and the presentation of each chapter remains at the high level reflected in our earlier volumes: to be current, pedagogical, and critical. The first chapters, as always, address a subject related to in-vivo biology. Gabby Elgavish addresses NMR spectroscopy of the intact heart. lain Campbell and colleagues present a state-of-the-art description of NMR methods for probing enzyme kinetics in intact cells and tissues. Klaus Mobius and Wolfgang Lubitz have produced a thorough review of the principles and applications of ENDOR spectroscopy in photobiology and biochemistry including discussions of liquid and solid state ENDOR as well as CIDEP-enhanced ENDOR. The final chapter by Hans Vogel and Sture Forsen addresses a contemporary problem in inorganic biochemistry, namely cation binding to calcium binding proteins. We are pleased to announce that a special forthcoming volume will be devoted entirely to the subject of "Spin Labeling: Theory and Applications (3rd compendium)." A substantial degree of progress has occurred in this important area of ESR in biology since the last treatise on the subject in 1979. Lastly, we acknowledge our colleagues in the field who continue to support this excellent series both as subscribers and contributors. We pledge to continue servicing the community as long as the need exists.
E-bok
PDF, Engelska, 2012687 kr
Läs direkt efter köp
We are again proud to present an excellent volume of contemporary topics in NMR and EPR to the biological community. The philosophy behind the volume and the presentation of each chapter remains at the high level reflected in our earlier volumes: to be current, pedagogical, and critical. The first chapters, as always, address a subject related to in-vivo biology. Gabby Elgavish addresses NMR spectroscopy of the intact heart. lain Campbell and colleagues present a state-of-the-art description of NMR methods for probing enzyme kinetics in intact cells and tissues. Klaus Mobius and Wolfgang Lubitz have produced a thorough review of the principles and applications of ENDOR spectroscopy in photobiology and biochemistry including discussions of liquid and solid state ENDOR as well as CIDEP-enhanced ENDOR. The final chapter by Hans Vogel and Sture Forsen addresses a contemporary problem in inorganic biochemistry, namely cation binding to calcium binding proteins. We are pleased to announce that a special forthcoming volume will be devoted entirely to the subject of "Spin Labeling: Theory and Applications (3rd compendium)." A substantial degree of progress has occurred in this important area of ESR in biology since the last treatise on the subject in 1979. Lastly, we acknowledge our colleagues in the field who continue to support this excellent series both as subscribers and contributors. We pledge to continue servicing the community as long as the need exists.
E-bok
PDF, Engelska, 2013687 kr
Läs direkt efter köp
Biological magnetic resonance (NMR and EPR) is a rapidly expanding area of research with much activity in most universities and research institutions. International conferences are held biennially with an increasing number of participants. With the introduction of sophisticated and continuously im proving instrumentation, biological magnetic resonance is approaching the state of a common physical method in biochemical, biomedical, and bio logical research. The lack of monograpbs on the subject had been con spicuous for a long time. This gap started to close only recently. However, because of the rapid expansion and intensive research, many texts are dated by the time of their appearance. Therefore we have undertaken the editing of a series that is intended to provide the practicing chemist, biochemist, or biologist with the advances and progress in selected contemporary topics. In seeking to make the series as authoritative as possible, we have invited authors who have not only made significant contributions but who are also currently active in their fields. We hope that their expertise as well as their first hand experience as reflected in the chapters of this volume will be of benefit to the reader, inter alia, in planning his own experiments and in critically evaluating the current literature.
Del 1 - Biological Magnetic Resonance
Biological Magnetic Resonance
Häftad, Engelska, 2013
549 kr
Skickas inom 10-15 vardagar
Biological magnetic resonance (NMR and EPR) is a rapidly expanding area of research with much activity in most universities and research institutions. International conferences are held biennially with an increasing number of participants. With the introduction of sophisticated and continuously im proving instrumentation, biological magnetic resonance is approaching the state of a common physical method in biochemical, biomedical, and bio logical research. The lack of monograpbs on the subject had been con spicuous for a long time. This gap started to close only recently. However, because of the rapid expansion and intensive research, many texts are dated by the time of their appearance. Therefore we have undertaken the editing of a series that is intended to provide the practicing chemist, biochemist, or biologist with the advances and progress in selected contemporary topics. In seeking to make the series as authoritative as possible, we have invited authors who have not only made significant contributions but who are also currently active in their fields. We hope that their expertise as well as their first hand experience as reflected in the chapters of this volume will be of benefit to the reader, inter alia, in planning his own experiments and in critically evaluating the current literature.
E-bok
PDF, Engelska, 2012687 kr
Läs direkt efter köp
Judging from the articles published in Biochemistry, magnetic resonance techniques (NMR and ESR) are now among the most popular methods in biochemical research. The series Biological Magnetic Resonance, the fifth volume of which we are proudly presenting, is intended to provide authori tative coverage of topics of current interest. Previous volumes have covered a number of aspects in a thorough and pedagogical fashion rarely found in other publications in this field. Continuing to fulfill the mission of the series, this volume presents a chapter by Baxter, Mackenzie, and Scott on the applications of carbon-13 NMR spectroscopy in investigations of methabolic pathways in vivo. Blom berg and Ruterjans give a comprehensive summary of the use of nitrogen-15 NMR in studies of systems of biological interest. Phosphorus-3I NMR investigations of enzyme systems are described by Rao. Tsai and Bruzik outline the principles of and summarize the state-of-the-art advances in the 18 use of oxygen isotopes e 70 and 0) in phosphorus-3I and oxygen-17 NMR studies of biophosphates. Lipid-protein interactions as reflected in ESR and NMR data are discussed by Devaux. We wish to thank the authors for their cooperation in maintaining the and continued high standards of the series.
Häftad, Engelska, 2012
549 kr
Skickas inom 10-15 vardagar
Judging from the articles published in Biochemistry, magnetic resonance techniques (NMR and ESR) are now among the most popular methods in biochemical research. The series Biological Magnetic Resonance, the fifth volume of which we are proudly presenting, is intended to provide authori tative coverage of topics of current interest. Previous volumes have covered a number of aspects in a thorough and pedagogical fashion rarely found in other publications in this field. Continuing to fulfill the mission of the series, this volume presents a chapter by Baxter, Mackenzie, and Scott on the applications of carbon-13 NMR spectroscopy in investigations of methabolic pathways in vivo. Blom berg and Ruterjans give a comprehensive summary of the use of nitrogen-15 NMR in studies of systems of biological interest. Phosphorus-3I NMR investigations of enzyme systems are described by Rao. Tsai and Bruzik outline the principles of and summarize the state-of-the-art advances in the 18 use of oxygen isotopes e 70 and 0) in phosphorus-3I and oxygen-17 NMR studies of biophosphates. Lipid-protein interactions as reflected in ESR and NMR data are discussed by Devaux. We wish to thank the authors for their cooperation in maintaining the and continued high standards of the series.
E-bok
PDF, Engelska, 2012687 kr
Läs direkt efter köp
We have now reached our sixth volume in a series which has somewhat unintentionally become an annual event. While we still intend to produce a volume only if a suitable number of excellent chapters in the forefront of biological magnetic resonance are available, our philosophy is to present a pedagogical yet critical description and review of selected topics in mag netic resonance of current interest to the community of biomedical scien tists. This volume fulfills our goals well. As always, we open the volume with a chapter which directly addresses an in vivo biological problem: Phil Bolton''s presentation of new techniques in measuring 31 P NMR in cells. Lenkinski''s chapter on the theory and applications of lanthanides in protein studies covers the details, highlights, and pitfalls of analysis of these com plexes in biochemical NMR. Reed and Markham summarize the interpreta tion of EPR spectra of manganese in terms of structure and function of proteins and enzymes. Dalton and colleagues describe the applications to biological problems of the relatively new capability of time domain ESR. Finally, we are pleased to offer a departure from mainstream magnetic resonance with the comprehensive and stimulating chapter by Gus Maki on the theory, instrumentation, and applications of optically detected magnetic resonance.
Del 6 - Biological Magnetic Resonance
Biological Magnetic Resonance
Volume 6
Häftad, Engelska, 2012
549 kr
Skickas inom 10-15 vardagar
We have now reached our sixth volume in a series which has somewhat unintentionally become an annual event. While we still intend to produce a volume only if a suitable number of excellent chapters in the forefront of biological magnetic resonance are available, our philosophy is to present a pedagogical yet critical description and review of selected topics in mag netic resonance of current interest to the community of biomedical scien tists. This volume fulfills our goals well. As always, we open the volume with a chapter which directly addresses an in vivo biological problem: Phil Bolton's presentation of new techniques in measuring 31 P NMR in cells. Lenkinski's chapter on the theory and applications of lanthanides in protein studies covers the details, highlights, and pitfalls of analysis of these com plexes in biochemical NMR. Reed and Markham summarize the interpreta tion of EPR spectra of manganese in terms of structure and function of proteins and enzymes. Dalton and colleagues describe the applications to biological problems of the relatively new capability of time domain ESR. Finally, we are pleased to offer a departure from mainstream magnetic resonance with the comprehensive and stimulating chapter by Gus Maki on the theory, instrumentation, and applications of optically detected magnetic resonance.
Del 26 - Biological Magnetic Resonance
Ultra High Field Magnetic Resonance Imaging
Häftad, Engelska, 2014
2 241 kr
Skickas inom 10-15 vardagar
From the early examples of what was to be called MRI, extending the te- nique to higher fields than those of less than 0. 1 T used in the first large-volume instruments was a goal, but the way there was unclear. The practical success of large superconducting magnets was a surprise, and the astonishment continued as they developed fields from 0. 3 T to 0. 6 T to 1. 5 T, and even more, up to the now common 3T systems, and a few 4T machines, and now to about 100 times the fields used in the first medium- and large-bore devices. In the early machines, low radiofrequencies of 4 MHz or so meant that RF coil designs were simple (even inexperienced undergraduates could design and build such circuits with little knowledge of more than DC electrical circuits), and the forces on gradient coils were small. The effects of magnetic susceptibility in- mogeneity in and around the object being imaged were negligible, and RF penet- tion depths were not a problem for human-scale samples. Everything began to change as higher fields and higher frequencies came into use, and the earlier idyllic simplicities began to seem quaint. The trend continued, however, driven by the increased signal-to-noise ratios and the resultant higher resolutions and speed available, and sophisticated engineering became more and more essential, not only for magnets but for gradient systems and radiofrequency transmitters and receivers, but also for better software for modeling and correcting distortions.
Del 27 - Biological Magnetic Resonance
ESR Spectroscopy in Membrane Biophysics
Häftad, Engelska, 2014
2 176 kr
Skickas inom 10-15 vardagar
Spectroscopic methods are not only important as an analytical tool, they also provide information about fundamental physical and chemical properties of molecules, the molecular and electronic structure, and the dynamic behaviour of molecules. Starting from a comprehensive quantum mechanical description, ESR Spectroscopy in Membrane Biophysics introduces the optical (IR, Raman, UV/Vis, CD, fluorescence and laser spectroscopy) and magnetic resonance (1D and 2D-NMR, ESR) techniques. ESR Spectroscopy in Membrane Biophysics is a timely review of the increasing interest in using spin-label ESR as an alternative structural technique for NMR or X-ray diffraction. It is aimed at training an audience to learn ESR spectroscopy to determine membrane protein structures, conformational dynamics and protein-lipid interaction.
Del 30 - Biological Magnetic Resonance
fMRI: From Nuclear Spins to Brain Functions
Inbunden, Engelska, 2015
3 358 kr
Skickas inom 10-15 vardagar
This volume explores the revolutionary fMRI field from basic principles to state-of-the-art research. It covers a broad spectrum of topics, including the history of fMRI's development using endogenous MR blood contrast, neurovascular coupling, pulse sequences for fMRI, quantitative fMRI; fMRI of the visual system, auditory cortex, and sensorimotor system; genetic imaging using fMRI, multimodal neuroimaging, brain bioenergetics and function and molecular-level fMRI. Comprehensive and intuitively structured, this book engages the reader with a first-person account of the development and history of the fMRI field by the authors. The subsequent sections examine the physiological basis of fMRI, the basic principles of fMRI and its applications and the latest advances of the technology, ending with a discussion of fMRI’s future. fMRI: From Nuclear Spins to Brain Function, co-edited by leading and renowned fMRI researchers Kamil Ugurbil, Kamil Uludag and Lawrence Berliner, is an ideal resource for clinicians and researchers in the fields of neuroscience, psychology and MRI physics.
E-bok
PDF, Engelska, 20153 137 kr
Läs direkt efter köp
This volume explores the revolutionary fMRI field from basic principles to state-of-the-art research. It covers a broad spectrum of topics, including the history of fMRI''s development using endogenous MR blood contrast, neurovascular coupling, pulse sequences for fMRI, quantitative fMRI; fMRI of the visual system, auditory cortex, and sensorimotor system; genetic imaging using fMRI, multimodal neuroimaging, brain bioenergetics and function and molecular-level fMRI. Comprehensive and intuitively structured, this book engages the reader with a first-person account of the development and history of the fMRI field by the authors. The subsequent sections examine the physiological basis of fMRI, the basic principles of fMRI and its applications and the latest advances of the technology, ending with a discussion of fMRI’s future. fMRI: From Nuclear Spins to Brain Function, co-edited by leading and renowned fMRI researchers Kamil Ugurbil, Kamil Uludag and Lawrence Berliner, is an ideal resource for clinicians and researchers in the fields of neuroscience, psychology and MRI physics.
Del 32 - Biological Magnetic Resonance
Protein NMR
Modern Techniques and Biomedical Applications
Inbunden, Engelska, 2015
1 124 kr
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This book covers new techniques in protein NMR, from basic principles to state-of-the-art research. It covers a spectrum of topics ranging from a “toolbox” for how sequence-specific resonance assignments can be obtained using a suite of 2D and 3D NMR experiments and tips on how overlap problems can be overcome. Further topics include the novel applications of Overhauser dynamic nuclear polarization methods (DNP), assessing protein structure, and aspects of solid-state NMR of macroscopically aligned membrane proteins.This book is an ideal resource for students and researchers in the fields of biochemistry, chemistry, and pharmacology and NMR physics. Comprehensive and intuitively structured, this book examines protein NMR and new novel applications that include the latest technological advances. This book also has the features of:• A selection of various applications and cutting-edge advances, such as novel applications of Overhauser dynamic nuclear polarization methods (DNP) and a suite of 2D and 3D NMR experiments and tips on how overlap problems can be overcome• A pedagogical approach to the methodology• Engaging the reader and student with a clear, yet critical presentation of the applications
E-bok
PDF, Engelska, 20151 408 kr
Läs direkt efter köp
This book covers new techniques in protein NMR, from basic principles to state-of-the-art research. It covers a spectrum of topics ranging from a “toolbox” for how sequence-specific resonance assignments can be obtained using a suite of 2D and 3D NMR experiments and tips on how overlap problems can be overcome. Further topics include the novel applications of Overhauser dynamic nuclear polarization methods (DNP), assessing protein structure, and aspects of solid-state NMR of macroscopically aligned membrane proteins.
This book is an ideal resource for students and researchers in the fields of biochemistry, chemistry, and pharmacology and NMR physics. Comprehensive and intuitively structured, this book examines protein NMR and new novel applications that include the latest technological advances.
This book also has the features of:
• A selection of various applications and cutting-edge advances, such as novel applications of Overhauser dynamic nuclear polarization methods (DNP) and a suite of 2D and 3D NMR experiments and tips on how overlap problems can be overcome
• A pedagogical approach to the methodology
• Engaging the reader and student with a clear, yet critical presentation of the applications
Del 32 - Biological Magnetic Resonance
Protein NMR
Modern Techniques and Biomedical Applications
Häftad, Engelska, 2016
1 124 kr
Skickas inom 10-15 vardagar
This book covers new techniques in protein NMR, from basic principles to state-of-the-art research. It covers a spectrum of topics ranging from a “toolbox” for how sequence-specific resonance assignments can be obtained using a suite of 2D and 3D NMR experiments and tips on how overlap problems can be overcome. Further topics include the novel applications of Overhauser dynamic nuclear polarization methods (DNP), assessing protein structure, and aspects of solid-state NMR of macroscopically aligned membrane proteins.This book is an ideal resource for students and researchers in the fields of biochemistry, chemistry, and pharmacology and NMR physics. Comprehensive and intuitively structured, this book examines protein NMR and new novel applications that include the latest technological advances. This book also has the features of:• A selection of various applications and cutting-edge advances, such as novel applications of Overhauser dynamic nuclear polarization methods (DNP) and a suite of 2D and 3D NMR experiments and tips on how overlap problems can be overcome• A pedagogical approach to the methodology• Engaging the reader and student with a clear, yet critical presentation of the applications
Del 30 - Biological Magnetic Resonance
fMRI: From Nuclear Spins to Brain Functions
Häftad, Engelska, 2016
2 464 kr
Skickas inom 10-15 vardagar
This volume explores the revolutionary fMRI field from basic principles to state-of-the-art research. It covers a broad spectrum of topics, including the history of fMRI's development using endogenous MR blood contrast, neurovascular coupling, pulse sequences for fMRI, quantitative fMRI; fMRI of the visual system, auditory cortex, and sensorimotor system; genetic imaging using fMRI, multimodal neuroimaging, brain bioenergetics and function and molecular-level fMRI. Comprehensive and intuitively structured, this book engages the reader with a first-person account of the development and history of the fMRI field by the authors. The subsequent sections examine the physiological basis of fMRI, the basic principles of fMRI and its applications and the latest advances of the technology, ending with a discussion of fMRI’s future. fMRI: From Nuclear Spins to Brain Function, co-edited by leading and renowned fMRI researchers Kamil Ugurbil, Kamil Uludag and Lawrence Berliner, is an ideal resource for clinicians and researchers in the fields of neuroscience, psychology and MRI physics.
Del 28 - Biological Magnetic Resonance
High Resolution EPR
Applications to Metalloenzymes and Metals in Medicine
Häftad, Engelska, 2014
2 241 kr
Skickas inom 10-15 vardagar
Metalloproteins comprise approximately 30% of all known proteins, and are involved in a variety of biologically important processes, including oxygen transport, biosynthesis, electron transfer, biodegradation, drug metabolism, proteolysis, and hydrolysis of amides and esters, environmental sulfur and nitrogen cycles, and disease mechanisms. EPR spectroscopy has an important role in not only the geometric structural characterization of the redox cofactors in metalloproteins but also their electronic structure, as this is crucial for their reactivity. The advent of x-ray crystallographic snapshots of the active site redox cofactors in metalloenzymes in conjunction with high-resolution EPR spectroscopy has provided detailed structural insights into their catalytic mechanisms.This volume was conceived in 2005 at the Rocky Mountain Conference on Analytical Chemistry (EPR Symposium) to highlight the importance of high-resolution EPR spectroscopy to the structural (geometric and electronic) characterization of redox active cofactors in metalloproteins. We have been fortunate to have enlisted internationally recognized experts in this joint venture to provide the scientific community with an overview of high-resolution EPR and its application to metals in biology. This volume, High-Resolution EPR: Applications to Metalloenzymes and Metals in Medicine, covers high-resolution EPR methods, iron proteins, nickel and copper enzymes, and metals in medicine. An eloquent synopsis of each chapter is provided by John Pilbrow in the Introduction. A second volume, Metals in Biology: Applications of High-Resolution EPR to Metalloenzymes, will appear later this year covering the complement of other metalloproteins.One of the pioneers in the development of pulsed EPR and its application to metalloproteins was Arthur Schweiger, whose contribution we include in this volume. Unfortunately, he passed away suddenly during the preparation of this volume. The editors andcoauthors are extremely honored to dedicate this volume to the memory of Arthur Schweiger in recognition of his technical advances and insights into pulsed EPR and its application to metalloproteins. Arthur was extremely humble and treated everyone with equal respect. He was a gifted educator with an ability to explain complex phenomena in terms of simple intuitive pictures, had a delightful personality, and continues to be sadly missed by the community.It is an honor for the editors to facilitate the dissemination of these excellent contributions to the scientific community. Suggestions for future volumes are always appreciated.