Lewis A Barness – författare

Despite the advent of powerful technological advances, the cornerstone of patient care remains the history and physical examination. In this era of lab tests and, in a system dominated by "adult medicine," the special approach to the unique examination of infants and children is often lost. In the Handbook of Pediatric Physical Diagnosis, the highly respected pediatrician Lewis Barness, and noted pediatrician and pathologist, Enid Gilbert-Barness, present clear descriptions and guidelines for the examination of the pediatric patient in an objective, analytical, and humanistic manner. With concise, clearly written text covering both common and difficult diagnoses, and aided by a wealth of tables, charts, and illustrations, this new edition includes more information on differential diagnosis, and has a new fresh look.

Laboratory tests are an integral part in the diagnosis of diseases in the pediatric age group and are commonly an essential part of the diagnostic workup, which is important for selecting the most appropriate treatment. Many new techniques and laboratory studies have been introduced in the last few years and many have replaced older methods that have become obsolete. It has become essential to the practice of modern pediatrics to be familiar with advances in laboratory medicine and it has become important to meet the demands of the practicing physician. As before, the complexity and sophistication of many tests exceed the capabilities of many office or small hospital facilities. However, when necessary, these tests can be referred to specialized reference laboratories. As in the previous edition, the text of this revised second edition is divided into categories of disease with a brief outline of signs and symptoms that remain integral and essential for diagnosis. This is followed by diagnostic tests, including the most important methods for diagnosis with updates in molecular procedures, DNA, probes, monoclonal antibodies, polymerase chain reaction, immunocytochemical and cytochemical staining, flow cytometry, and cytogenetics. Additional tables and algorithms have been included to add simplification, clarify and to expedite the understanding and selection of diagnostic tests. ""Clinical Use of Pediatric Diagnostic Tests"" aims to become essential for the needs of pediatricians, family practitioners, students, residents, pathologists, nurses, practitioners and laboratory technicians.

The 2nd Edition of Metabolic Diseases provides readers with a completely updated description of the Foundations of Clinical Management, Genetics, and Pathology. A distinguished group of 31 expert authors has contributed 25 chapters as a tribute to Enid Gilbert-Barness and the late Lewis Barness--- both pioneers in this topic. Enid’s unique perspectives on the pathology of genetic disorders and Lew’s unsurpassed knowledge of metabolism integrated with nutrition have inspired the contributors to write interdisciplinary descriptions of generally rare, and always challenging, hereditary metabolic disorders. Discussions of these interesting genetic disorders are organized in the perspective of molecular abnormalities leading to morphologic disturbances with distinct pathology and clinical manifestations.The book emphasizes recent advances such as development of improved diagnostic methods and discovery of new, more effective therapies for many of the diseases. It includes optimal strategies for diagnosis and information on access to specialized laboratories for specific testing. The target audience is a wide variety of clinicians, including pediatricians, neonatologists, obstetricians, maternal-fetal specialists, internists, pathologists, geneticists, and laboratorians engaged in prenatal and/or neonatal screening. In addition, all scientists and health science professionals interested in metabolic diseases will find the comprehensive, integrated chapters informative on the latest discoveries. It is our hope that the 2nd Edition will open new avenues and vistas for our readers and that they will share with us the interest, excitement and passion of the research into all these challenging disorders.

All forms of life require food materials in certain minimum amounts to insure an active life and successful reproduction. Nutrition is concerned with what these materials are, how they function, what effects they have when absent and what happens to them when ingested. During the past two centuries such nutritional disorders as scurvy, beriberi, rickets and pellagra have been discovered, successfully treated and eradicated by physicians in developed countries. In this century, such noted researchers as Rose, Meyerhof and Krebs have contributed enormously to the field of nutrition. Currently, research is evolving new concepts and facts so rapidly that the average practitioner can hardly keep current, even in his own field of medicine. Bona fide research by universities and governmental agen­ cies has produced voluminous information, much of which seems contra­ dictory and therefore tends to confuse the general public, particularly in the area of potential carcinogens. This confusion has prompted consumer groups, politicians, and social welfarists to bring pressures and demands on medical schools and prac­ titioners of medicine to increase their knowledge and concern in the field of nutrition. Taking advantage of and adding to this confusion are the health food faddists and cultists, some only for monetary gain and others with a real religious zeal.