Lisa Vozza - Böcker

This book is an excursion into the drug development process, from the initial conception in a chemical or molecular biology lab, via tests in isolated cells and animals, to the stage of clinical trials. The human body is a complex ecosystem where little is conclusively known in terms of its response to medication, for both sick and healthy individuals. The considerable degree of uncertainty inherent in health-related research can lead to approval of controversial medicines, particularly in high-stakes scenarios and medical crises. Real-life examples are drawn on here to explain the decision making processes behind the acceptance of new drugs, disproving misconceptions around medicines by delving into the history and current practice of the drug development process.Originally written in Italian, How Medicines are Born helps patients, students, public health officials physicians, healthcare practitioners and biomedical scientists make informed decisions on the benefits and disadvantages of select medicine based on an understanding of the history of drug development.Published in Italian (2014), M D'Incalci & L Vozza, Come Nascono le Medicine; La scienza imperfetta dei farmaci. Bologna: ZanichelliRelated Link(s)

This book is an excursion into the drug development process, from the initial conception in a chemical or molecular biology lab, via tests in isolated cells and animals, to the stage of clinical trials. The human body is a complex ecosystem where little is conclusively known in terms of its response to medication, for both sick and healthy individuals. The considerable degree of uncertainty inherent in health-related research can lead to approval of controversial medicines, particularly in high-stakes scenarios and medical crises. Real-life examples are drawn on here to explain the decision making processes behind the acceptance of new drugs, disproving misconceptions around medicines by delving into the history and current practice of the drug development process.Originally written in Italian, How Medicines are Born helps patients, students, public health officials physicians, healthcare practitioners and biomedical scientists make informed decisions on the benefits and disadvantages of select medicine based on an understanding of the history of drug development.Published in Italian (2014), M D'Incalci & L Vozza, Come Nascono le Medicine; La scienza imperfetta dei farmaci. Bologna: ZanichelliRelated Link(s)

A new coronavirus, most likely spilled over from an animal species, has plunged us into the third epidemic of this kind in the last twenty years, against which there were neither vaccines nor therapies.While we argue over the future of humanity, vulnerable to the ecological and environmental degradation that has enabled the pandemic, extraordinary technologies have been developed to combat infectious diseases. In just eleven months it was possible to develop, test and produce the vaccines that are gradually enabling us to escape the SARS-CoV-2 nightmare. In addition, with the legacy of the technologies developed against COVID-19, we will be able to overcome antimicrobial resistance—a slow but inexorable pandemic.As vaccinologists are churning out increasingly precise and effective solutions, vaccine acceptance seems to be receding. Outbreaks of preventable diseases have prompted the health authorities of several countries to make childhood vaccinations mandatory again. Much remains to be done, but a public capable of distinguishing authoritative voices from misleading ones will be able to enjoy the vaccines of tomorrow more widely. Vaccines in the Global Era is an easy-to-read book that can be read by virtually anyone who wants to learn about the importance, effectiveness and safety of vaccines in preventing infectious diseases.Vaccines are cheap, save countless lives, and are more effective than the best medicines. Let's try to make the best use of them for the health of the people and animals living together on this beautiful planet.