M. Gilles-Baillien – författare

The aim of this symposium was to provide a framework for fruitful discussion on intestinal transport, not only for advanced scientists but also for younger people starting in this field of research. Invited lectures, communications and poster presentations were focused on four central themes, all treating the prop­ erties of the sole intestinal epithelium, deliberately leaving aside problems dealing with more integrative functions of the whole intestine. The importance of motility or blood circulation, for instance, is certainly capital in the overall intestinal function, but these aspects by themselves deserve another meeting. This volume has compiled the manuscripts of the invited lectures which sub­ stantially comprised the four sessions of the Symposium. Part 1 is designed to emphasize actual knowledge of the transport of water, inorganic as well as organic ions and molecules across the isolated intestinal epithelium. An enormous wave of investigations has emerged from studies per­ formed with "Ussing chambers", which roused interest in studies on absorption mechanisms and subsequently on secretory processes. This has triggered off a trend to research on isolated cells as absorption and secretion are the main func­ tion of the different cell types constituting the intestinal epithelium. In this first session not only the importance of the parallel arrangement of these different cellular entities is stressed, but also the role played by the paracellular route.

The aim of this symposium was to provide a framework for fruitful discussion on intestinal transport, not only for advanced scientists but also for younger people starting in this field of research. Invited lectures, communications and poster presentations were focused on four central themes, all treating the prop­ erties of the sole intestinal epithelium, deliberately leaving aside problems dealing with more integrative functions of the whole intestine. The importance of motility or blood circulation, for instance, is certainly capital in the overall intestinal function, but these aspects by themselves deserve another meeting. This volume has compiled the manuscripts of the invited lectures which sub­ stantially comprised the four sessions of the Symposium. Part 1 is designed to emphasize actual knowledge of the transport of water, inorganic as well as organic ions and molecules across the isolated intestinal epithelium. An enormous wave of investigations has emerged from studies per­ formed with "Ussing chambers", which roused interest in studies on absorption mechanisms and subsequently on secretory processes. This has triggered off a trend to research on isolated cells as absorption and secretion are the main func­ tion of the different cell types constituting the intestinal epithelium. In this first session not only the importance of the parallel arrangement of these different cellular entities is stressed, but also the role played by the paracellular route.

This volume is one of those published from the proceedings of the invited lectures to the First International Congress of Comparative Physiology and Biochemistry I organized at Liege (Belgium) in August 1984 under the auspices of the Section of Comparative Physiology and Biochemistry of the International Union of Biological Sciences. In a general foreword to these different volumes, it seems to me appropriate to consider briefly what may be the comparative approach. Living organisms, beyond the diversity of their morphological forms, have evolved a widespread range of basic solutions to cope with the different problems, both organismal and environmental with which they are faced. Soon after the turn of the century, some biologists realized that these solutions can be best comprehended in the frame­ work of a comparative approach integrating results of physiological and biochemical studies done at the organismic, cellular and molecular levels. The development of this approach amongst both physiologists and biochemists remained, however, extremely slow until recently.