Malin Parmar – författare

Athymic Nude Rat Brain Atlas will provide the first stereotaxic brain atlas of the athymic nude rat (Crl:NIH-Foxn1rnu), a T-cell deficient rat model commonly used in experimental studies and pre-clinical safety and efficacy studies. This 2D vector-based atlas contains coronal, sagittal, and horizontal brain sections of an athymic rat brain rendered from a single cleared specimen, placed in a computerized 3D environment. The maps enable readers to better calculate co-ordinates to target specific structures for toxin, virus, or cell delivery using stereotaxic surgery. This atlas will be a valuable resource for any neuroscientist who wishes to work with nude rats in experimental and pre-clinical studies.- Contains coronal, sagittal, and horizontal maps of young adult athymic nude rat brain, spaced with a distance of 0.2 or 0.25 mm- Uses "flat skull" Bregma and Lambda as anatomical landmarks for correct placement in the 3D environment- Anatomical structures and nomenclature follow the standard set by the Paxinos and Watson rat brain atlases- Includes a map of the dopamine projection system as well as the distribution of the A8-A14 dopamine cell groups- Allows for easy read-out of coordinates for precise injections using stereotactic surgery