Malini Basu – författare

This book provides up-to-date insights into the COVID-19 disease, addressing its outbreak, pathogenesis, biology, treatment interventions, and consequences as a global health crisis. Divided into six sections, the book covers a detailed examination of various facets of the disease. Section I delves into the host's genetic and epigenetic mechanisms in response to COVID-19. Section II focuses on disease diagnosis, providing valuable perspectives on kits, nucleic acid testing, immunological assays, imaging-based diagnosis, and variant-specific SARS-COV-2 detection. Section III covers cytokine storm, inflammation, and immunity, including the modulation of signaling pathways leading to immune evasion and persistence. Section IV reveals drug repurposing, exploring antiviral, anti-inflammatory, anti-platelet drugs, and target-based drug discovery. Section V explains the evolution of vaccine development including DNA, RNA, subunit, and viral vaccines. Finally, Section VI explores COVID-19's impact on associated comorbidities, ranging from cancer and cardiac issues to neurological damages and economic consequences.The book is relevant for scientists, and researchers working on pathogenesis, development, implementation, host-pathogen interactions, and drug repurposing of COVID-19 disease.

This book provides up-to-date insights into the COVID-19 disease, addressing its outbreak, pathogenesis, biology, treatment interventions, and consequences as a global health crisis. Divided into six sections, the book covers a detailed examination of various facets of the disease. Section I delves into the host's genetic and epigenetic mechanisms in response to COVID-19. Section II focuses on disease diagnosis, providing valuable perspectives on kits, nucleic acid testing, immunological assays, imaging-based diagnosis, and variant-specific SARS-COV-2 detection. Section III covers cytokine storm, inflammation, and immunity, including the modulation of signaling pathways leading to immune evasion and persistence. Section IV reveals drug repurposing, exploring antiviral, anti-inflammatory, anti-platelet drugs, and target-based drug discovery. Section V explains the evolution of vaccine development including DNA, RNA, subunit, and viral vaccines. Finally, Section VI explores COVID-19's impact on associated comorbidities, ranging from cancer and cardiac issues to neurological damages and economic consequences.The book is relevant for scientists, and researchers working on pathogenesis, development, implementation, host-pathogen interactions, and drug repurposing of COVID-19 disease.

This book offers a definitive and comprehensive exploration of precision medicine, capturing both its foundational principles and cutting-edge innovations. Organized into six  sections, it guides readers from the basics of individualized healthcare to the advanced application of genomics, epigenomics, pharmacogenomics, and artificial intelligence in cancer treatment. Through detailed cancer-specific chapters—covering gliomas, head & neck cancers, breast, lung, prostate, colon, pancreatic, and other malignancies—the book delivers in-depth insights into molecular profiling, diagnosis, and personalized therapy strategies. Beyond scientific advances, it critically addresses the ethical, clinical, and social dimensions of precision medicine, preparing clinicians, researchers, and policymakers to navigate challenges and harness the future opportunities in this transformative field. By blending scientific rigor with forward-looking perspectives, this volume positions itself as an authoritative reference for oncology researchers, clinicians, bioinformaticians, pharmaceutical scientists, and graduate students seeking to understand and contribute to the future of personalized healthcare.