Marc Humbert – författare
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5 produkter
5 produkter
940 kr
Skickas inom 10-15 vardagar
Written by internationally recognized experts, Pulmonary Hypertension bridges the gap between pulmonology and cardiology to provide clinicians in both disciplines with knowledge of the signs, symptoms, diagnosis, and pharmacologic and surgical treatments for pulmonary hypertension (PH). Through the use of clinical trials, this ground-breaking text supplies a comprehensive review of both the primary and secondary clinical and investigative aspects of this condition. Discussing controversies and concepts in PH diagnosis and management, this guide explores: classification and epidemiology, pathology, pathogenesis, genetics, and diagnosis of PHcauses of the condition, such as idiopathic pulmonary arterial hypertension (IPAH)PAH-complicating connective tissue diseases (CTD), congenital heart diseases, human immunodeficiency virus (HIV), and other disordersthe mechanisms, toxicities, and efficacy of therapeutic agentsthe role of combination therapies, novel agents, and future directionsPH in specific patient populations such as pregnant and critically-ill patients in the ICU
3 470 kr
Skickas inom 10-15 vardagar
Written by internationally recognized experts, Pulmonary Hypertension bridges the gap between pulmonology and cardiology to provide clinicians in both disciplines with knowledge of the signs, symptoms, diagnosis, and pharmacologic and surgical treatments for pulmonary hypertension (PH). Through the use of clinical trials, this ground-breaking text supplies a comprehensive review of both the primary and secondary clinical and investigative aspects of this condition. Discussing controversies and concepts in PH diagnosis and management, this guide explores: classification and epidemiology, pathology, pathogenesis, genetics, and diagnosis of PHcauses of the condition, such as idiopathic pulmonary arterial hypertension (IPAH)PAH-complicating connective tissue diseases (CTD), congenital heart diseases, human immunodeficiency virus (HIV), and other disordersthe mechanisms, toxicities, and efficacy of therapeutic agentsthe role of combination therapies, novel agents, and future directionsPH in specific patient populations such as pregnant and critically-ill patients in the ICU
285 kr
Skickas inom 5-8 vardagar
3 505 kr
Skickas inom 5-8 vardagar
Pharmacotherapy of Pulmonary Hypertension
3 505 kr
Skickas inom 5-8 vardagar
This volume focuses on current evidence-based pharmacological treatments of various forms of pulmonary hypertension and provides a comprehensive review of the latest developments in this area. The first part of the book covers the definition, classification, pathophysiology, pathology, biomarkers and animal models of the disease, thus laying the conceptual basis for what follows. The middle section provides an overview of the established therapies, such as calcium channel blockers, prostanoids, endothelin receptor antagonists, phosphodiesterase-5 inhibitors and inhaled nitric oxide. The last section explores novel pathways and emerging therapeutic approaches including soluble guanylate cyclase stimulators, Rho-kinase inhibitors, inhibitors of serotonin receptors and transporters, peptide growth factors, vasoactive peptides, modulators of redox equilibrium and cyclic nucleotide homeostasis, as well as immunosuppressive and anti-proliferative agents. Particular attention is given to the clinical applications of these experimental therapies, that are on the horizon. The book thus spans the continuum from basic science to clinical applications.