Mark A. Atkinson - Böcker

Our understanding of the genetics and pathophysiology of animal models for autoimmune diseases such as type 1 diabetes and multiple sclerosis has increased significantly in the past few years. The central themes of this volume are the necessity for novel and improved models, the optimal use of information from animal models to understand pathogenesis of the human disease, and the rational development of novel immunotherapeutics. This volume is intended to foster discussion on the utility of currently available animal models, to suggest methods for improving upon present models, and to advance translational research in these fields.NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas.ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member

This volume an overview of current research in the field of immunology as it relates to diabetes. Topics covered include: autoantibody markers for type 1 diabetes; cellular immune markers for type 1 diabetes; animal models of type 1 diabetes; the pancreas in type 1 diabetes; genetics of type 1 diabetes; the role of toll-like receptors and innate immunity in type 1 diabetes; cell-based therapies for type 1 diabetes; environmental and mechanistic causes of type 1 diabetes; mechanisms of beta-cell death; role of the immune response in type 1 diabetes; and islet transplantation. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas.ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member