Markus Geisler – författare

This book is devoted to the fascinating superfamily of plant ATP-binding cassette (ABC) transporters and their variety of transported substrates. It highlights their exciting biological functions, covering aspects ranging from cellular detoxification, through development, to symbiosis and defense. Moreover, it also includes a number of chapters that center on ABC transporters from non-Arabidopsis species.ABC proteins are ubiquitous, membrane-intrinsic transporters that catalyze the primary (ATP-dependent) movement of their substrates through biological membranes. Initially identified as an essential aspect of a vacuolar detoxification process, genetic work in the last decade has revealed an unexpectedly diverse variety of ABC transporter substrates, which include not only xenobiotic conjugates, but also heavy metals, lipids, terpenoids, lignols, alkaloids and organic acids.The discovery that members of the ABCB and ABCG family are involved in the movement of phytohormones has further sparked their exploration and provided a new understanding of the whole family. Accordingly, the trafficking, regulation and structure-function of ABCB-type auxin transporters are especially emphasized in this book.

This book is devoted to the fascinating superfamily of plant ATP-binding cassette (ABC) transporters and their variety of transported substrates. It highlights their exciting biological functions, covering aspects ranging from cellular detoxification, through development, to symbiosis and defense. Moreover, it also includes a number of chapters that center on ABC transporters from non-Arabidopsis species.ABC proteins are ubiquitous, membrane-intrinsic transporters that catalyze the primary (ATP-dependent) movement of their substrates through biological membranes. Initially identified as an essential aspect of a vacuolar detoxification process, genetic work in the last decade has revealed an unexpectedly diverse variety of ABC transporter substrates, which include not only xenobiotic conjugates, but also heavy metals, lipids, terpenoids, lignols, alkaloids and organic acids.The discovery that members of the ABCB and ABCG family are involved in the movement of phytohormones has further sparked their exploration and provided a new understanding of the whole family. Accordingly, the trafficking, regulation and structure-function of ABCB-type auxin transporters are especially emphasized in this book.

Due to their sessile lifestyle, plants need to efficiently adapt to changing environmental conditions during their life cycle. Nutrient acquisition from the soil has to be able to adapt to considerable fluctuations in concentrations to ensure adequate distribution between tissues, cells and organelles. The storage and retrieval of nutrients, metabolites or toxic substances in vacuoles plays an important part in cellular homeostasis in plants. The long-range transport and maintenance of turgor is critically dependent on the availability of water and rate of evaporation, while at the same time photosynthetic products have to be transported to all plant parts. As a result plants contain a large number of ATP-dependent pumps and secondary transporters that, in order to adapt to the changing environment, need to be regulated by a complex network of sensing and signaling mechanisms.Plants share many basic elements of signal transduction with animals, but also contain plant-specific signaling molecules and mechanisms. In this volume, the role of transporters and pumps in the regulation of movement, long-range transport and compartmentalization of water, solutes, nutrients and classical signaling molecules is highlighted, and the function, regulation and membrane-transporter interaction and their roles in plant signaling controlling plant physiology and development are discussed.