Martin Field - Böcker

Computational and theoretical tools for understanding biological processes at the molecular level is an exciting and innovative area of science. Using these methods to study the structure, dynamics and reactivity of biomacromolecules in solution, computational chemistry is becoming an essential tool, complementing the more traditional methods for structure and reactivity determination. Modelling Molecular Structure and Reactivity in Biological Systems covers three main areas in computational chemistry; structure (conformational and electronic), reactivity and design. Initial sections focus on the link between computational and spectroscopic methods in the investigation of electronic structure. The use of Free Energy calculations for the elucidation of reaction mechanisms in enzymatic systems is also discussed. Subsequent sections focus on drug design and the use of database methods to determine ADME (absorption, distribution, metabolism, excretion) properties. This book provides a complete reference on state of the art computational chemistry practised on biological systems. It is ideal for researchers in the field of computational chemistry interested in its application to biological systems.

In Creating Community-Led and Self-Build Homes, Martin Field explores the ways in which people and communities across the UK have been striving to create the homes and neighbourhood communities they want.Giving context to contemporary practices in the UK, the book examines ‘self-build housing’ and ‘community-led housing’, discussing the commonalities and distinctions between these in practice, and what could be learned from other initiatives across Europe. Individual methods and models of local practice are explored - including cohousing, cooperatives, community land trusts, empty homes and other intentional communities - and an examination is made of what has constrained such initiatives to date and how future policies and practice might be shaped.