Max Diem - Böcker

Cancer is the second largest cause of death (after heart disease) in North America and Europe. Statistics from many countries serve constantly to inform us of how prevalent cancer is worldwide, even though one particular variation may be more predominant is one geographical region than another. The Traumatic cost in human lives, the dramatic cost of treatment and the need for rapidly advancing diagnoses and improving diagnostic methods for cancer, are clear for all to see. Current histopathological techniques for the detection and classification of cancer often lead to ambiguous diagnoses. Infrared and Raman spectroscopy have the potential to provide fast, accurate complementary techniques for the detection of many different forms of cancer. This book contains ten state-of-the-art chapters on the application of these techniques to the detection and classification of prostate, lymphatic, cervical, head and neck, and esophageal cancers, as well as reports on the application of vibrational spectroscopy to the study of individual human cells, and the identification of micro-organisms and erythrocytes, which should be of importance to spectroscopists and medical professionals alike. This book provides an up-to-date account of the practical means, applications and potential of mid-infrared and Raman spectroscopy for the medical diagnosis of diseased tissue and cells. It will be of significant interest both to vibrational spectroscopists involved in developing technique for medical diagnosis, and to clinicians, histopathologists, medical practitioners and students working in the field, with whom the spectroscopists must work closely in multi-disciplinary teams.

Modern Vibrational Spectroscopy and Micro-Spectroscopy: Theory, Instrumentation and Biomedical Applications unites the theory and background of conventional vibrational spectroscopy with the principles of microspectroscopy. It starts with basic theory as it applies to small molecules and then expands it to include the large biomolecules which are the main topic of the book with an emphasis on practical experiments, results analysis and medical and diagnostic applications.  This book is unique in that it addresses both the parent spectroscopy and the microspectroscopic aspects in one volume. Part I covers the basic theory, principles and instrumentation of classical vibrational, infrared and Raman spectroscopy. It is aimed at researchers with a background in chemistry and physics, and is presented at the level suitable for first year graduate students. The latter half of Part I is devoted to more novel subjects in vibrational spectroscopy, such as resonance and non-linear Raman effects, vibrational optical activity, time resolved spectroscopy and computational methods. Thus, Part 1 represents a short course into modern vibrational spectroscopy.Part II is devoted in its entirety to applications of vibrational spectroscopic techniques to biophysical and bio-structural research, and the more recent extension of vibrational spectroscopy to microscopic data acquisition. Vibrational microscopy (or microspectroscopy) has opened entirely new avenues toward applications in the biomedical sciences, and has created new research fields collectively referred to as Spectral Cytopathology (SCP) and Spectral Histopathology (SHP). In order to fully exploit the information contained in the micro-spectral datasets, methods of multivariate analysis need to be employed. These methods, along with representative results of both SCP and SHP are presented and discussed in detail in Part II.

Enables students to understand, apply, and retain key concepts in general chemistry Understanding Essential Chemistry offers a unique and approachable supplement to standard general chemistry textbooks, designed specifically to aid students in mastering fundamental principles. Drawing on extensive classroom experience, chemistry professor Max Diem presents key concepts in an uninterrupted flow, allowing students to follow a clear and straightforward path to comprehension. With a logical, algebraic framework, the book is structured to build students’ confidence by breaking down complex topics into manageable pieces and encouraging critical thinking at every step. Aimed at STEM majors, this book includes checkpoints with example problems and final answers to reinforce concepts and promote independent problem-solving skills. By methodically emphasizing basic understanding, this hands-on guide gives students the tools to grasp the core chemistry principles necessary for success in their courses, labs, and future studies. A must-have “survival guide” to boost student confidence in the subject, the text: Presents chemistry concepts in a streamlined, continuous format for easier comprehension and retentionEncourages independent critical thinking with targeted example problems with provided solutionsSupports any primary general chemistry textbook, making it adaptable for various curriculaAllows students to assess their understanding at key points in the materialIncludes additional math tutorials in the Chapter for students needing a refresher in essential mathematical skillsThis guide is an essential supplement for undergraduate first-year Chemistry courses for STEM majors, especially those in pre-medical, engineering, and science programs.

Schlägt die Brücke zwischen Quantentheorie und Spektroskopie! Spektroskopie ist das Arbeitspferd zur Struktur- und Eigenschaftsaufklärung von Molekülen und Werkstoffen. Um die verschiedenen spektroskopischen Methoden verstehen, kompetent anwenden und die Ergebnisse interpretieren zu können, ist grundlegendes Wissen der Quantenmechanik erforderlich: Konzepte wie stationäre Zustände, erlaubte und verbotene Übergänge, Elektronenspin und Elektron-Elektron-, Elektron-Photon- und Elektron-Phonon-Wechselwirkung sind die Grundlagen jeglicher spektroskopischen Methode. Quantenmechanische Grundlagen der Molekülspektroskopie führt ein in die quantenmechanischen Grundlagen der Molekülspektroskopie, geschrieben vom Standpunkt eines erfahrenen Anwenders spektroskopischer Methoden. Das Lehrbuch vermittelt das notwendige Hintergrundwissen, um Spektroskopie zu verstehen: Energie-Eigenzustände, Übergänge zwischen diesen Zuständen, Auswahlregeln und Symmetrie. Zahlreiche Spektroskopiearten werden diskutiert, etwa Fluoreszenz-, Oberflächen-, Raman-, IR- und Spin-Spektroskopie. * Perfekte Balance: ausreichend Physik und Mathematik, um Spektroskopie zu verstehen, ohne die Leserinnen und Leser mit unnötigem Formalismus zu überfrachten * Relevantes Thema: spektroskopische Methoden werden in allen Bereichen der Chemie, Biophysik, Biologie und Materialwissenschaften angewandt * Auf die Bedürfnisse Studierender zugeschnitten: der Autor ist ein erfahrener Hochschullehrer, der auch schwierige Aspekte verständlich vermittelt * Hervorragende Didaktik: detaillierte Erklärungen und durchgerechnete Beispiele unterstützen das Verständnis; zahlreiche Aufgaben mit Lösungen im Anhang erleichtern das Selbststudium Geschrieben für Studierende der Chemie, Biochemie, Materialwissenschaften und Physik, bietet Quantenmechanische Grundlagen der Molekülspektroskopie umfassendes Lernmaterial zum Verständnis der Molekülspektroskopie.