Meena Vangalapati – författare

Master's Thesis from the year 2012 in the subject Engineering - Chemical Engineering, Andhra University (Andhra University College of Engineering (A)), course: M.Tech Bio Technology, language: English, abstract: Herbal drug product has a special place in the world of pharmaceuticals. Terminalia chebula is a deciduous tree, used in traditional medicines. It is reported to contain various bio chemical compounds such as tannins, chebulinic acid, ellagic acid, gallic acid, punicalagin, flavonoids etc. It has been reported as antioxidant, antidiabetic, antibacterial, antiviral, antifungal, anticancerous, antiulcer, antimutagenic, wound healing activities etc. The optimization of physico-chemical parameters like effects of different solvents, soaking time, extraction time with hexane, particle size, different solvent percentages, different volumes of hexane with ethanol and methanol as solvents and pH for the extraction of Total Phenolic Content, Chebulinic acid and Quercetin were studied. The extraction was carried out by employing various organic solvents using Soxhlet extractor method. Ethanol was found to be the best solvent for the extraction of Chebulinic acid from Terminalia chebula species. Soxhlet extractor was carried out using ethanol at different extraction times to verify the mathematical model proposed in this work. The optimization of physico-chemical parameters required for obtaining the highest production of Chebulinic acid using Baker s yeast (Saccharomyces cerevisia.Among the extraction process (Batch, Soxhlet& Fermentation process) the highest Chebulinic acid production was obtained from fermentation process. The partition coefficient for fermentation, soxhlet & batch extraction were found to be 3.83, 2.0 & 0.64. The extraction of Chebulinic acid from Terminalia chebula by Soxhlet extraction and purify the Chebulinic acid by using Column chromatography. Chebulinic acid showed many bioactivities including inhibition of cancer cell growth, inhibiting the contractile responses of cardiovascular muscles, anti-fungal, anti-bacterial activities etc. Finally the Chebulinic acid extraction from Terminalia chebula plays a vital role in medicine, biotechnology and various pharmacological activities.

Research Paper (postgraduate) from the year 2016 in the subject Engineering - Chemical Engineering, grade: A, Andhra University (College of Engineering), course: Chemical Engineering, language: English, abstract: The aim of the present study is to optimize and model the removal of Two Azo and Two Anthra-Quinone Dyes from the dye effluent using Tunic of Allium cepa derived activated carbon using RSM. The relationship between dye removal efficiency and three main independent parameters including Temperature, Solution pH and Adsorbent Dosage were evaluated by applying central composite design (CCD) and Box-Behnken design (BBD). Water Has the high importance in industrial ad domestic areas, Where Industries consume a lot of water and releases highly toxic effluents which are really harmful to the environment containing the toxic metals like Cr, Cd, Pd, Ti, Zn and many harmful dyes etc. Textile effluent dyes are targeted I the present work which exist in two forms (i) True Color (ii) Apparent color. There are various dyes used in the textile industries among which majority of dye stuffs are majorly based on azodyes which are used to dye cotton fabric and anthra-quinone dyes. Azo Dyes: Determination of azo dyes are categorized by the presence of (-N=N-) azo group as chromophore. Azo dyes are generally found in synthetic dye classes. Previously azo dyes were applied to cotton which involves the reactions with chemical components which reacts to form the dye into the fiber or on the surface. Primuline red and Para red fall into this group of azo dyes introduces in 1880 s.Azo dyes are mostly used in cotton fabric. Anthra- quinone dyes: Determination of anthra- quinone dyes are characterized by carbonyl group (>C=O) as chromophore. Other names of anthra- quinone are anthrachinon, dioxoanthracene and different trade names like Corbit and Hoelite. The dyes like Saffranin, indigo carmine, Alizarin, Red S, Crystal violet were chosen here from the textile effluent for the removal. The source materials used here are natural powders namely Tunic of Allium cepa and its activated carbon.