Michael A. Jones – författare

As the population of patients with acute or chronic kidney disease grows, healthcare professionals need a resource that optimizes drug effectiveness while minimizing potential toxicity.  Renal Pharmacotherapy is a comprehensive listing of dosage recommendations for patients with compromised renal function.  This up-to-date and evidence-based reference closes several identified knowledge gaps concerning medications eliminated by the kidneys.

Conveniently listed alphabetically by generic drug name, each drug has its own face page featuring typical dosing ranges, alternative dosing adjustments by strata of renal function, specific dosing for dialysis and other dosing schemes.

This work will satisfy the dosing information needs of busy physicians involved in pharmacotherapy for patients with kidney disease, as well as pharmacists, nurses and students.

This book provides a comprehensive mathematical description and analysis of the delegate allocation processes in the US Democratic and Republican presidential primaries, focusing on the role of apportionment methods and the effect of thresholds—the minimum levels of support required to receive delegates.  The analysis involves a variety of techniques, including theoretical arguments, simplicial geometry, Monte Carlo simulation, and examination of presidential primary data from 2004 to 2020. The book is divided into two parts: Part I defines the classical apportionment problem and explains how the implementation and goals of delegate apportionment differ from those of apportionment for state representation in the US House of Representatives and for party representation in legislatures based on proportional representation. The authors then describe how delegates are assigned to states and congressional districts and formally define the delegate apportionment methods usedin each state by the two major parties to allocate delegates to presidential candidates. Part II analyzes and compares the apportionment methods introduced in Part I based on their level of bias and adherence to various notions of proportionality. It explores how often the methods satisfy the quota condition and quantifies their biases in favor or against the strongest and weakest candidates. Because the methods are quota-based, they are susceptible to classical paradoxes like the Alabama and population paradoxes. They also suffer from other paradoxes that are more relevant in the context of delegate apportionment such as the elimination and aggregation paradoxes. The book evaluates the extent to which each method is susceptible to each paradox. Finally, it discusses the appointment of delegates based on divisor methods and notions of regressive proportionality.

This book appeals to scholars and students interested in mathematical economics and political science, with an emphasis on apportionment and social choice theory.